Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
Would cells lacking all D cyclins undergo cell cycle arrest or phosphorylate pRb through other means and progress through the cell cycle
Mouse development and cell proliferation in the absence of D-cyclins. Near normal BrdU incorporation Heart defect in TKO Mouse development and cell proliferation in the absence of D-cyclins. Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A, Sicinska E, Geng Y, Yu Q, Bhattacharya S, Bronson RT, Akashi K, Sicinski P. Cell. 2004 Aug 20;118(4):477-91.
- Page 1 and 2: Tumor Initiating Cells, Cell Cycle
- Page 3: Hallmarks of Cancer: The Next Gener
- Page 9 and 10: Isolation of tumorigenic cells. Al-
- Page 11 and 12: Phenotypic diversity in tumors aris
- Page 13: A model depicting the hierarchical
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- Page 24 and 25: For example: The phosphatidylinosit
- Page 26 and 27: Notes: • On average: 24 gains and
- Page 28 and 29: Regulation of cell cycle progressio
- Page 30 and 31: Phosphorylation of the retinoblasto
- Page 32 and 33: Fluctuation of cyclin levels during
- Page 34 and 35: Cell cycle-dependent phosphorylatio
- Page 36 and 37: Figure 8.23d The Biology of Cancer
- Page 38 and 39: LxCxE binding LxCxE motif Figure 8.
- Page 40 and 41: Actions of CDK inhibitors Figure 8.
- Page 42 and 43: Figure 8.15a The Biology of Cancer
- Page 44 and 45: Regulation of p27 localization AKT
- Page 46 and 47: How do p21 and p27 regulate G1 cycl
- Page 48: As D type cyclins accumulate during
- Page 53 and 54: Molecular Analyses of G1 Phase Prog
- Page 55 and 56: cyclin E phosphorylates p27 on Thr-
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Mouse development <strong>and</strong> cell proliferation in the absence of D-cyclins.<br />
Near normal BrdU incorporation<br />
Heart defect in TKO<br />
Mouse development <strong>and</strong> cell proliferation in the absence of D-cyclins.<br />
Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A, Sicinska E, Geng Y, Yu Q, Bhattacharya S, Bronson RT, Akashi K,<br />
Sicinski P.<br />
<strong>Cell</strong>. 2004 Aug 20;118(4):477-91.
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