Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation Stages during the cell cycle when pRb in under-phosphorylated Chen PL, Scully P, Shew JY, Wang JY, Lee WH. Cell. 1989 Sep 22;58(6):1193-8. Karen Buchkovich, Linda A. Duffy and Ed Harlow Cell. 1989 Sep 22;58(6):1097-105. James A. DeCaprio, John W. Ludlow, Dennis Lynch, Yusuke Furukawa, James Griffin, Helen Piwnica-Worms, Chun-Ming Huang and David M. Livingston 1989 Cell ;58(6):1085-95.
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Micro-injection of Rb protein during this period blocks entry into S phase Goodrich DW, Wang NP, Qian YW, Lee EY, Lee WH.Cell. 1991 18;67(2):293-302. Goodrich DW, Wang NP, Qian YW, Lee EY, Lee WH.Cell. 1991 67(2):293-302.
- Page 1 and 2: Tumor Initiating Cells, Cell Cycle
- Page 3: Hallmarks of Cancer: The Next Gener
- Page 9 and 10: Isolation of tumorigenic cells. Al-
- Page 11 and 12: Phenotypic diversity in tumors aris
- Page 13: A model depicting the hierarchical
- Page 17: Implications of CSC model to chemot
- Page 20 and 21: Proto-oncogenes promote hallmarks o
- Page 22 and 23: Hallmark Tumor suppressor Function
- Page 24 and 25: For example: The phosphatidylinosit
- Page 26 and 27: Notes: • On average: 24 gains and
- Page 28 and 29: Regulation of cell cycle progressio
- Page 32 and 33: Fluctuation of cyclin levels during
- Page 34 and 35: Cell cycle-dependent phosphorylatio
- Page 36 and 37: Figure 8.23d The Biology of Cancer
- Page 38 and 39: LxCxE binding LxCxE motif Figure 8.
- Page 40 and 41: Actions of CDK inhibitors Figure 8.
- Page 42 and 43: Figure 8.15a The Biology of Cancer
- Page 44 and 45: Regulation of p27 localization AKT
- Page 46 and 47: How do p21 and p27 regulate G1 cycl
- Page 48: As D type cyclins accumulate during
- Page 51 and 52: Mouse development and cell prolifer
- Page 53 and 54: Molecular Analyses of G1 Phase Prog
- Page 55 and 56: cyclin E phosphorylates p27 on Thr-
- Page 57 and 58: Positive and negative regulation of
The retinoblastoma gene product regulates progression through the<br />
G1 phase of the cell cycle.<br />
Micro-injection of Rb<br />
protein during this<br />
period blocks entry<br />
into S phase<br />
Goodrich DW, Wang NP, Qian YW, Lee EY, Lee WH.<strong>Cell</strong>. 1991 18;67(2):293-302.<br />
Goodrich DW, Wang NP, Qian YW, Lee EY, Lee WH.<strong>Cell</strong>. 1991 67(2):293-302.
Change language