Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
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signal<br />
+<br />
Signaling, oncogenes, tumor-suppressors<br />
<strong>and</strong> non-oncogene addiction<br />
Oncogene<br />
-<br />
<strong>Tumor</strong> suppressor<br />
-<br />
Negative regulator that is not mutated/lost in cancer<br />
+<br />
Positive regulator that is not activated in cancer<br />
but its inactivation blocks signaling - non-oncogene<br />
addiction
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