Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
Tumor Initiating Cells, Cell Cycle Control and Cancer Stem Cells
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Can non-TICs spontaneously reverse into TICs<br />
Primary tumors<br />
Transplantation<br />
Secondary tumors<br />
Normal <strong>and</strong> neoplastic nonstem cells can spontaneously convert to a stem-like state.<br />
Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M,<br />
Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA.<br />
Proc Natl Acad Sci U S A. 2011 May 10;108(19):7950-5.