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The Indian Journal of Tuberculosis - LRS Institute of Tuberculosis ...

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168<br />

SUMMARIES OF PAPERS<br />

Changing pr<strong>of</strong>ile <strong>of</strong> lung cancers presentation<br />

in Govt. General Hospital, Chennai<br />

R. Prabhakaran, V. Sundar, B. Rajagopalan, D.<br />

Ranganathan, and R. Athurunnisa Begum.<br />

Aim: To study the changing pr<strong>of</strong>ile <strong>of</strong> lung cancers<br />

in year 1995 and year 2005.<br />

Method: In the combined retrospective and<br />

prospective study, cases <strong>of</strong> lung cancers were<br />

scanned for distinctive (clinic pathological features,<br />

histropathological types and biological behaviour <strong>of</strong><br />

the tumour.<br />

Results: Total 83 diagnosed cases <strong>of</strong> lung cancer<br />

in 1995 were analysed in details. Male female<br />

ratio was 5.91 : 1, age range was from 35 to 87<br />

years and maximum number <strong>of</strong> patients were<br />

between 46-64 years. Most common<br />

histopathological type in male was squamous cell<br />

carcinoma; most common histopathological type in<br />

females was adeno-carcinoma. Most common<br />

respiratory symptoms were cough 83.13%,<br />

hemoptysis 37.34% and chest pain 73.49%. Out <strong>of</strong><br />

83 patients, 61 patients were smokers, 22 were nonsmokers.<br />

Most common cell type in smokers was<br />

squamous cell carcinoma followed by adenocarcinoma.<br />

Among non-smokers most common cell<br />

type was adeno carcinoma.<br />

All small cell carcinoma patients were<br />

smokers. 61.44% were having clubbing. Commonest<br />

presentation in chest radiograph was mass lesion<br />

(75.90%). Sputum cytology positive 7.22%, post<br />

FOB sputum cytology positive 15.66%, CT guided<br />

biopsy positive 85.36%, FOB guided biopsy positive<br />

74.99%, USG guided biopsy positive 100% were<br />

noted.<br />

This pattern has a few important differences<br />

when compared with recent 1 year study conducted<br />

in the same hospital in 2004 - 2005.<br />

Conclusion: <strong>The</strong>re is an increasing occurrence <strong>of</strong><br />

lung cancer with a few definite changing patterns.<br />

Improved diagnostic method may be responsible.<br />

Smoking is the commonest etiological factor.<br />

Although squamous cell carcinoma is commonest<br />

type but adeno carcinoma is also not uncommon.<br />

Statistical analysis <strong>of</strong> risk factors with PFT<br />

abnormalities among traffic police personnel<br />

using a new risk scoring system<br />

A. Chitrakumar, K. Jagannath and R.<br />

Altharunnisa Begum<br />

Objective: Identifying pulmonary function<br />

abnormalities among traffic police personnel serving<br />

in the city <strong>of</strong> Chennai and correlating the same with<br />

their respiratory symptoms and other risk factors as<br />

evaluated with a new scoring system introduced by<br />

us.<br />

Methodology: All the eligible traffic police personnel<br />

were subjected to a respiratory questionnaire<br />

prepared specifically for the study and subsequently<br />

measurement <strong>of</strong> BP, Oxygen saturation and PFT by<br />

spirometer were done. All <strong>of</strong> them had a MMR. In<br />

all among 825 traffic police personnel screened, 768<br />

were found eligible for inclusion in the study.<br />

Findings: Pulmonary function abnormalities<br />

correlated well with persons with respiratory<br />

symptoms, age <strong>of</strong> the individual, smoking habit and<br />

duration <strong>of</strong> service in polluted environment.<br />

<strong>The</strong> multiple logistic regression analysis<br />

revealed that respiratory symptoms were found to<br />

be significant independent variables contributing very<br />

significantly for abnormal PFT variables, i.e. FEVI<br />

(or 1.79; p0.02), PEFR (or 1.58; p0.04), FEF 25-75<br />

(or 2.40; p0.0001)<br />

<strong>The</strong> new computer based scoring system<br />

on risk factors clearly predicts that increase in risk<br />

score is positively associated with increased<br />

proportion <strong>of</strong> PFT abnormalities in high risk groups.<br />

Conclusion: <strong>The</strong> newly introduced risk scoring<br />

system will be quite useful in identifying or<br />

predicting pulmonary function abnormalities<br />

among respiratory symptomatics with other<br />

confounding variables. Among persons exposed<br />

to environmental pollution, evaluation <strong>of</strong> small<br />

airway function may help us to identify their<br />

disability at the earliest.<br />

<strong>Indian</strong> <strong>Journal</strong> <strong>of</strong> <strong>Tuberculosis</strong>

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