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Ventilator-Associated Event Prevention - NYS Partnership for Patients

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Diagnostic Strategies:<br />

Clinical vs. Bacteriologic<br />

Clinical<br />

• Dx as subsequent slide<br />

• Sensitivity vs specificity<br />

altered based on number<br />

of criteria used<br />

• Etiology defined by semiquantitative<br />

cultures<br />

• Emphasizes prompt abx<br />

• Abx choice based on risk<br />

factors<br />

• Therapy modified by<br />

response and cultures<br />

• Over sensitive, less<br />

specific<br />

Bacteriologic<br />

• Uses quantitative cultures<br />

of lower resp secretions<br />

(BAL or PSB) to define<br />

pna and org<br />

• Decision on initial abx<br />

still clinically based<br />

• Consistently finds less<br />

org than qualitative<br />

cultures<br />

• Less abx used<br />

• Findings not always<br />

consistent or reproducible<br />

• False neg may lead to<br />

under treatment

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