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Ventilator-Associated Event Prevention - NYS Partnership for Patients

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Randomized Controlled Trial and Meta-analysis<br />

of Oral Decontamination with 2% Chlorhexidine Solution<br />

<strong>for</strong> the <strong>Prevention</strong> of <strong>Ventilator</strong>-<strong>Associated</strong> Pneumonia<br />

207 patients randomized to receive oral care with 2%<br />

chlorhexidine solution vs normal saline<br />

VAP rate 4.9% (7/1000 ventilator days) in chlorhexidine group vs<br />

11.4% (21/1000 ventilator days) in normal saline group<br />

Conclusion: Oral decontamination with 2% chlorhexidine<br />

solution is an effective and safe method <strong>for</strong> preventing VAP in<br />

patients who receive mechanical ventilation.<br />

• Tantipong et al, Infect Control Hosp Epidemiology 2008;29: 131-136<br />

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