Ventilator-Associated Event Prevention - NYS Partnership for Patients
Ventilator-Associated Event Prevention - NYS Partnership for Patients
Ventilator-Associated Event Prevention - NYS Partnership for Patients
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Daily Interruption of Sedative infusions in<br />
Critically Ill <strong>Patients</strong> Undergoing Mechanical<br />
Ventilation<br />
Randomized, controlled trial of 128 adults on<br />
mechanical ventilation and continuous sedation.<br />
Compared daily interruptions until the patient was<br />
awake with interruptions only at the discretion of the<br />
clinicians in the ICU<br />
Median time of mechanical ventilation was 4.9 days in<br />
the intervention group and 7.3 days in the control group<br />
(p=0.004)<br />
Median LOS in the ICU was 6.4 days in the intervention<br />
group and 9.9 days in the control group (p=0.02)<br />
In-hospital mortality was 36% in intervention group<br />
and 47% in control group (p=0.25)<br />
• Kress et al, N Engl J Med 2000;342:1471-7
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