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Manual for Male Circumcision under Local Anaesthesia

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<strong>Male</strong> circumcision <strong>under</strong> local anaesthesia<br />

Version 3.1 (Dec09)<br />

Protection <strong>for</strong> women<br />

A study in Uganda observed lower rates of male-to-female<br />

transmission of HIV if the man was circumcised. 13 Among 47 couples<br />

in which the circumcised male partner was infected with HIV and<br />

whose viral load was below 50 000 copies per ml, none of the female<br />

partners became infected in two years. By contrast, 26 of the 147<br />

women whose HIV-infected partners were not circumcised became<br />

infected.<br />

A subsequent randomized controlled trial of circumcision among men<br />

with HIV infection did not confirm this result. It showed there might be<br />

a higher risk of HIV transmission to women in the first two years after<br />

the operation. 22<br />

A further observational study has shown a 40% lower risk of HIV<br />

infection in couples where the male partner was infected and the<br />

female partner not infected with HIV, but the reduction in risk was not<br />

significant. 23<br />

Other health benefits of circumcision<br />

A multicountry study 24 found a lower prevalence of human<br />

papillomavirus (HPV) infection in circumcised men than in<br />

uncircumcised men. HPV infection is a necessary causal factor <strong>for</strong><br />

cervical cancer and is associated with an increased risk of cancer of<br />

the vulva, vagina and anus in women, and of the penis and anus in<br />

men. Prospective studies have shown that circumcised men are less<br />

likely to have HPV infection. 25,26,27<br />

The incidence of invasive penile cancer is significantly lower in<br />

circumcised men than in uncircumcised men, though this condition is<br />

extremely rare. 28,10<br />

Acceptability of circumcision among African men<br />

Surveys and qualitative studies among young as well as older men in<br />

six African countries have found that a considerable proportion<br />

expressed interest in circumcision, ranging from 45% in Harare,<br />

Zimbabwe, to over 80% in a large survey in Botswana. 29 These<br />

studies indicate that many men would willingly <strong>under</strong>go circumcision if<br />

it could be per<strong>for</strong>med safely and at reasonable cost.<br />

In the surveys, the men reported that their main interest in<br />

circumcision was related to hygiene, infection control and, <strong>for</strong> some, a<br />

belief that condom use is easier <strong>for</strong> men who are circumcised.<br />

<strong>Male</strong> circumcision and HIV infection Chapter 1-6

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