PACT300 - Cumdente
PACT300 - Cumdente
PACT300 - Cumdente
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Photo-activated<br />
Therapy<br />
For all oral infections<br />
Periodontitis, Periimplantitis, Endo, Caries,<br />
Bone and Soft Tissue.<br />
In 20 seconds.
is a trademark of:
Photo-activated Therapy<br />
Photo-activated therapy is indispensable in modern<br />
medicine since the 1990s. For the treatment of tumors,<br />
skin diseases and wound infections.<br />
Since the middle of the 90s Univ.-Prof. Dr. Rainer Hahn has been working on<br />
photosensitizers and compatible light sources. Dr. Frank Schynowski is one of<br />
the most experienced chemist in the field of PACT. <strong>Cumdente</strong> has developed<br />
to a leading company in this field of dentistry and medicine.<br />
PACT ® : made in Tübingen, Germany.<br />
You can rely on our know-how and the efficacy of PACT ® .<br />
Your <strong>Cumdente</strong> team<br />
Univ.-Prof. Dr. med. dent. Rainer Hahn<br />
Dr. rer. nat. Frank Schynowski
PACT ® 300<br />
Device class<br />
Wavelength<br />
Laser Class<br />
Laser Diode Power<br />
Output Power<br />
Emission Time<br />
Light Guides<br />
Laser Activating<br />
Power Supply<br />
Working Time<br />
Class IIa (93/42/EEC)<br />
Laser Diode 632-644 nm<br />
2M (93/42/EEC)<br />
Approx. 410 mW<br />
Approx. 300 mW<br />
Irradiation time depending on indication<br />
from 20 s, audio signal after 20 s<br />
Plastic Applicator<br />
Contactor<br />
1 x Accumulator Li-Ion 3,7 V / 900mAh<br />
Approx. 80 applications with fully<br />
loaded accumulator<br />
Working Temperature 10–45 ºC<br />
Storage Temperature 0–50 ºC<br />
Dimensions L x W<br />
Weight<br />
155 mm x 18 mm<br />
Approx. 250 g<br />
PACT ® 300 Complete-Set<br />
• PACT ® 300 red light laser – handpiece incl. stand with integrated<br />
charging function<br />
• 2 pcs. of Light Guides Universal<br />
• 2 pcs. of Light Guides Endo<br />
• 2 pcs. of Light Guides XL<br />
• PACT ® Fluid Endo (2 x syringes each 0,6 ml)<br />
• PACT ® Gel Universal ( 2 x syringes each 1,0 ml)<br />
• Endo-Flex-Canulas (Pack at 10 pcs.)<br />
• 1 pc. PACT ® Laser-protective goggles<br />
• Case<br />
CUM 1071300
PACT ® Photosensitizer Fluid/Gel<br />
PACT ® Light Guides<br />
PACT ® Gel Universal<br />
Universal-photosensitizer-gel for PACT ® -Therapy<br />
• Pack at 10 syringes (Luer-Lock) each 1,0 ml<br />
CUM 1001433<br />
PACT ® Fluid Endo<br />
Highly fluid photosensitizer for PACT ® root<br />
canal »sterilization«<br />
• Pack at 10 syringes (Luer-Lock) each 0,6 ml<br />
CUM 1001434<br />
Endo-Flex-Canula<br />
For direct application of PACT ® Fluid / Gel<br />
• Pack at 10 pcs.<br />
CUM 1000601<br />
PACT ® Light Guide Universal<br />
Universal single-use light guide for PACT ® with<br />
spherical irradiation for perio/periimplantitis/<br />
caries/cavities/stump/soft tissue infections<br />
• Pack at 10 pcs.<br />
CUM 1001422<br />
PACT ® Light Guide Endo<br />
Endo single-use light guide for PACT ® with rodshaped<br />
irradiation for the root canal treatment<br />
• Pack at 10 pcs.<br />
CUM 1001423<br />
PACT ® Light Guide XL<br />
PACT ® single-use light guide with extensive<br />
irradiation for bone and soft tissue infections<br />
and others<br />
• Pack at 10 pcs.<br />
CUM 1001472
PACT ® 300<br />
Bacteria<br />
Fungi<br />
gram-positive<br />
gram-negative<br />
PACT ® Gel / Fluid<br />
Attribute Cell Walls<br />
Lipopolysaccharides (LPS)<br />
Ground State<br />
residence time PACT ®<br />
photosensitizer.<br />
LPS<br />
Fibrilla<br />
<br />
Cytoplasma<br />
Phospholipides<br />
Enzymes<br />
Proteines
Mode of Action<br />
PACT ®<br />
• kills gram-positive and gram-negative bacteria,<br />
analog to the mechanism of the granylocytes in<br />
our host response (activated oxygen)<br />
• destroys biofilms and cell walls<br />
• destroys bacterial lipopolysaccarides, phospholipides<br />
etc.<br />
• blocks bacteria enzymes and proteinases<br />
• reduces bacterial virulence<br />
• promotes tissue regeneration and collagene<br />
growth<br />
<br />
aO 2<br />
*<br />
aO 2<br />
*<br />
Excited State<br />
PACT ® 300 Laser activates<br />
the photosensitizer. Activated<br />
oxygen (aO 2<br />
*) is generated.<br />
aO 2<br />
*<br />
aO 2<br />
* aO 2<br />
*<br />
aO 2<br />
*<br />
aO 2<br />
*<br />
Tissue-Oxygen<br />
aO 2<br />
*<br />
Activated<br />
Oxygen*<br />
<br />
99,99 % killing rate<br />
of all bacteria, fungi and viruses by<br />
destroying their cell walls with aO 2<br />
*.<br />
Even clyndamycin and metronidazoleresistent<br />
germs. Spares somatic cells<br />
(cell membrane).
PACT ® 300<br />
99,99 % of all oral bacteria are killed during the<br />
20 s PACT ® -treatment. Without any side effects.<br />
No resistances.<br />
1.1 PACT ® - Perio Therapy<br />
Alternative to systemic and local antibiotics.<br />
For aggressive and chronic forms of periodontitis.<br />
Improves the tissue regeneration.<br />
Your advantages: Gentle closed therapy, even of<br />
deep (> 5 mm), bleeding (BOP) and refractory<br />
pockets. Perio surgery can be prevented, recall<br />
intervals can be extended.<br />
1.2 PACT ® -Periimplantitis Therapy<br />
For the closed and open application. Preserves the<br />
sensitive implant surface.<br />
Your advantage: Rapid healing.
Indication<br />
1.3 PACT ® -caries-/cavities-/stump-/soft tissue-<br />
»sterilisation«<br />
Eliminates bacteria deep into the dentine (tubules),<br />
reduces pulp infections, preserves the pulp.<br />
Your Advantage: Often reduces pulp necrosis.<br />
1.4 PACT ® -Endo Therapy<br />
Eliminates bacteria, also pathogenic germs in<br />
the root canal from deep down in the side canals,<br />
caverns and dentine tubules.<br />
Your Advantage: Elimination of germs also in the<br />
dentine walls.<br />
1.5 PACT ® -Bone and soft tissue therapy<br />
E.g. in infected alveolus, herpes simplex, membrane<br />
infections, with immediate implants and before<br />
augmentations etc.<br />
Your Advantage: Painless therapy without delayed<br />
wound healing.
PACT ® 300<br />
Broad spectrum bactericide<br />
PACT ® often replaces the dental antibiotic therapy, also in case of agressive periodontitis<br />
and periimplantitis.<br />
PACT ® can sustainably inactivate and dissolute biofilms, reduces viruses and fungi without<br />
any discoloration and without any side effects.<br />
PACT ® improves common treatments, e.g. scaling, root planing, root canal<br />
and caries treatment.<br />
PACT ® minimises problems in immediate implantation.<br />
PACT ® improves the treatment of bone infections, ulcers and dolor post.<br />
PACT ® improves the prognosis of bone and soft tissue surgery and of augmentations<br />
in implantology.<br />
PACT ® can be used easily and economically.<br />
PACT ® can be delegated to the assistant.<br />
PACT ® has over 10 years of experience and a wealth of scientific studies.<br />
PACT ® is recommended by german and international experts.<br />
Typical bacterial changes of microbial status after PACT ®<br />
therapy in a 6 mm molar pocket<br />
10 6 10 6<br />
antibiotic<br />
therapy limit<br />
10 5 10 5<br />
antibiotic<br />
therapy limit<br />
10 4 10 4<br />
10 3 10 3<br />
Aa Pg Tf Td Pi Pm Fn Cr En Ec Cs<br />
Aa Pg Tf Td Pi Pm Fn Cr En Ec Cs<br />
Aacomplex<br />
red complex<br />
orange<br />
complex<br />
orangeassociated<br />
complex<br />
green<br />
complex<br />
Aacomplex<br />
red complex<br />
orange<br />
complex<br />
orangeassociated<br />
complex<br />
green<br />
complex<br />
before<br />
after<br />
Shortcuts of bacteria nomenclature:<br />
Aa = Aggregatibacter actinomycetemcomitans<br />
Pg = Porphyromonas gingivalis<br />
Tf = Tannerella forsythia<br />
Td = Treponema denticola<br />
Pi = Prevotella intermedia<br />
Pm = Peptostreptococcus micros<br />
Fn = Fusobacterium nucleatum<br />
Cr = Campylobacter rectus<br />
En = Eubacterium nodatum<br />
Ec = Eikenella corrodens<br />
Cs = Capnocytophaga spec. (gingivalis,<br />
ochracea, sputigena)<br />
Bacterial loading<br />
10 3 : Bacterial load below detection limit<br />
10 4 : Bacterial load at detection limit<br />
10 5 : High bacterial load<br />
10 6 : Very high bacterial load
Clinic<br />
The tolonium chloride photosenitizer has been proven safe for the<br />
therapy of poisonings for a long time. Initially, such patients attracted<br />
attention by getting sensitised by light. As a result the photoactivated<br />
therapy with tolonium chloride was developed.<br />
Under irradiation with the PACT ® light source, the applied PACT ®<br />
sensitizer attacks (after a short residence time) the cell walls of<br />
bacteria, virus and fungi. Thereby, PACT ® is also effective against<br />
antibiotic resistant bacteria as well as deep under the surface.<br />
After therapy (from 20 seconds) the dye is rinsed of without residue.<br />
Nothing hinders the wound healing, nothing affects the aesthetic.<br />
Regeneration is promoted.
<strong>Cumdente</strong><br />
Deutschland / International<br />
<strong>Cumdente</strong> GmbH<br />
Paul-Ehrlich-Straße 11<br />
72076 Tübingen, Germany<br />
Fon +49 70 71 9 75 57 21<br />
Fax +49 70 71 9 75 57 22<br />
www.cumdente.com