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ABSTRACTS - World Psychiatric Association

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incomplete coverage of the HTR2C variants is proposed as the best<br />

cost-benefit ratio bias to fix.<br />

PO2.18.<br />

PREVALENCE OF GENERALIZED ANXIETY<br />

DISORDER IN A PRIMARY CARE CLINIC<br />

IN EAST MALAYSIA<br />

J.H. Ting, D.K. Catherinus<br />

Department of Psychological Medicine, Faculty of Medicine,<br />

University Malaya, Kuala Lumpur, Malaysia<br />

This study aimed to determine the prevalence of generalized anxiety<br />

disorder in patients attending an outpatient primary care clinic in a<br />

small town in East Malaysia. Patients attending the clinic were randomly<br />

selected to participate in the study. They were then interviewed<br />

to record their sociodemographic characteristics and were screened<br />

for generalized anxiety disorder by using the Mini International Neuropsychiatric<br />

Interview (MINI). A total of 203 patients participated in<br />

this study. The prevalence rate of generalized anxiety disorder (GAD)<br />

was estimated to be at 9.4%. Female patients were almost three times<br />

more likely to have a diagnosis of GAD when compared to men. The<br />

age group of 15-34 had the highest number of patients with GAD. The<br />

MINI proved to be easy to use and required only a short time for<br />

administration.<br />

PO2.19.<br />

FUNCTIONAL IMPAIRMENT RELATED<br />

TO PAINFUL PHYSICAL SYMPTOMS IN PATIENTS<br />

WITH GENERALIZED ANXIETY DISORDER<br />

WITH OR WITHOUT COMORBID MAJOR<br />

DEPRESSIVE DISORDER<br />

I. Romera, A.L. Montejo, F. Caballero, L. Caballero, J. Arbesu,<br />

I. Gilaberte<br />

Clinical Research Department, Lilly Spain; University<br />

of Salamanca; Sixth Health Area, Servicio Madrileño de Salud,<br />

Madrid; Hospital Puerta de Hierro, Madrid; Centro de Salud de<br />

la Eria, Oviedo, Spain<br />

This study aimed to assess the functional impairment related to the<br />

presence of painful physical symptoms (PPS) in patients suffering<br />

from generalized anxiety disorder (GAD) with or without comorbid<br />

major depressive disorder (MDD). This is post-hoc analysis of a<br />

cross-sectional study in patients attending primary care who received<br />

a diagnosis of GAD (Mini International <strong>Psychiatric</strong> Interview). A<br />

control group (no GAD, no MDD) was consecutively selected.<br />

Patients were considered to have PPS if Visual Analog Scale overall<br />

pain score was >30. Functioning was assessed by the Sheehan Disability<br />

Scale (SDS). ANCOVA models (including age, gender, comorbidity)<br />

were used. Of 7152 patients included, 981 had GAD, 559<br />

with comorbid MDD. Of those, 436 (78.0%) had PPS, higher than<br />

the percentage in those with GAD without MDD (249 of 422, 59%)<br />

and than controls patients (95 of 336, 28.3%). Functioning of both<br />

GAD groups was clearly worse when PPS were present (p

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