ABSTRACTS - World Psychiatric Association

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went functional magnetic resonance imaging while performing a task requiring implicit or explicit processing of emotional facial stimuli. Behavioral data showed higher scores on the Emotion Control scale of the BFQ for GT relative to GG subjects (p=0.05). Furthermore, imaging data revealed an interaction between genotype and task on amygdala and prefrontal activity (p
PO1.214. NEURAL REPRESENTATION OF ATTACHMENT STYLE USING FUNCTIONAL MAGNETIC RESONANCE IMAGING: METHOD DEVELOPMENT A. Winston, G. Galynker, S. Fox, J. Prosser, R. Kelly, C. Muran Department of Psychiatry and Behavioral Sciences, Beth Israel Medical Center, New York, NY, USA Attachment, the degree of maternal-child security experienced during development, is considered to be a significant determinant of ability to appropriately evaluate and respond to social cues throughout life. Evidence indicates that attachment style influences psychotherapeutic outcome. We present a method for examining the neurobiology of attachment styles using functional neuroimaging. Four healthy adult female volunteers completed the Adult Attachment Interview (AAI) and underwent blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) scanning. Attachment stimuli consisted of black and white photographic images of the subject’s mother, father, a close female friend, female strangers and male strangers. Statistical parametric mapping was used to assess functional neural activity. FSL 3.2, a library of analysis tools for brain imaging data, was used for data analysis. First level and higher level analyses were performed. The relationship between attachment experience and regional brain function was assessed by correlating AAI with fMRI data. PO1.215. EFFECT OF THREE FUNCTIONAL POLYMORPHISMS OF THE HUMAN DOPAMINE D2 RECEPTOR GENE ON COGNITION R. Romano, B. Gelao, P. Taurisano, G. Caforio, A. Di Giorgio, A. Rampino, A. Porcelli, L. Fazio, L. Lo Bianco, A. Papazacharias, R. Masellis, A. Papp, W. Sadee, G. Blasi, M. Nardini, A. Bertolino <strong>Psychiatric</strong> Neuroscience Group, Department of Psychiatry and Neurology, University of Bari; Program in Pharmacogenomics, Department of Pharmacology, and Department of Psychiatry, Division of Human Genetics, College of Medicine and College of Pharmacy, Ohio State University, Columbus, OH, USA Cortical and subcortical dopamine D2 receptor (DRD2) signaling has been implicated in cognitive processes, including working memory, attention and executive functions. Aim of this study was to investigate the association of cognition with three frequent DRD2 SNPs, two intronic SNPs, respectively SNP19 (rs#1076560)(G/T) and SNP17 (rs#2283265)(G/T), which affect mRNA splicing, and SNP2 in the promoter region (rs#12364283)(T/C) affecting total mRNA expression. We recruited a large sample of healthy subjects (n=77-119) matched for socio-demographic variables across the three DRD2 SNPs. All subjects underwent a set of neuropsychological tests assessing working memory (N-back), sustained attention (CPT), executive function (WCST), cognitive flexibility (TMT A-B), and memory (WMS). Behavioral performance was evaluated in terms of accuracy and reaction time. Moreover, all raw scores were transformed to z scores to calculate the composite score using the mean of z scores for each subject. ANOVA demonstrated a significant main effect of DRD2 SNP19 on composite score (p
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P World Psychiatry OFFICIAL JOURNAL
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WORLD PSYCHIATRIC ASSOCIATION INTER
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RS2. New advances in diffusion magn
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SW8. Treatments for pregnant women
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cologic treatment options are now a
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elation to particular treatments an
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chotherapy (TFP), an outgrowth of p
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obtaining open employment. Secondar
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tion of diagnosis-specific suicide
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US7. ADVANCES IN THE MANAGEMENT OF
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those following birth. Very little
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US14.2. COMMON AND RARE GENETIC VAR
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cause within 12 months was 63 (Kapl
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sentations, and the onset of effica
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US23.3. NEUROGENETIC MECHANISMS OF
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and physical disorders meets proble
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parent-child relationship. A ration
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specifically, these studies have ei
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RS3.5. USING ANTIDEPRESSANTS (PLUS
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BOLD signal differences in prefront
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affective states and to increase in
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account for over fifty per cent of
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sequencing of the pathway to care o
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RS14.2. OBSESSIVE-COMPULSIVE DISORD
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RS16. SUPPORTED EMPLOYMENT FOR PEOP
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RS18. CURRENT STATE AND FUTURE PROS
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RS20. BRAIN SYSTEMS AND PSYCHOSIS R
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andomly recruited from the Montpell
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model requires a conceptual shift f
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familiar with psychological vulnera
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RS26.5. IMPLICATIONS OF RECOVERY: A
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cotherapy, remain unclear. These ar
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RS30.2. COMBINATION THERAPIES FOR P
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RS32.2. CHRONOTHERAPEUTICS TO TREAT
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RS34. THE EFFECTS OF PSYCHIATRIC CO
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teristics than an African American
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WO6. MANAGEMENT OF MENTALLY DISORDE
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WO14. PRACTICAL ISSUES IN THE LONG-
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espectively; for women with any psy
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SS3. THE ASSOCIATION BETWEEN IMPULS
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and blood samples were used for tol
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(the need to avoid harm to a patien
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SS9. IMPLEMENTING MENTAL HEALTH CAR
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SS11. RECOVERY BEYOND RHETORIC (org
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Romanian admission to the European
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SS14.2. SUBJECT-SPECIFIC EEG ANALYS
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SS16. HOPE IN PSYCHIATRY (organized
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SS18. TOWARDS A CONSENSUS ON ETHICS
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duced drugs that were marketed as a
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treated for unipolar and bipolar de
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long-term individual therapy, the t
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provide a defence or to accept a de
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SS28.2. DOCTORS’ HEALTH AND ADDIC
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SS30.3. EVIDENCE-BASED PSYCHOTHERAP
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has created a unique challenge for
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SS35. ACCESS TO MENTAL HEALTH CARE:
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SS36.3. BEHAVIOURAL AND COGNITIVE-B
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SS38.2. DEPRESSION AND DEMENTIA: LE
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need to show what it is doing to ad
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the individual’s personhood (in e
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taken into account and mood disorde
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and psychiatric services at all lev
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chose the field of psychoneuroimmun
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ices to families (particularly chil
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suffer from comorbid depression. In
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American countries, that the majori
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ZS10.5. STIGMA IN UKRAINE AND POST-
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chotherapeutic schools, such as the
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NRS2. GENETICS AND MOLECULAR BIOLOG
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NRS3.2. EARLY DETECTION AND INTERVE
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NRS4.4. DEPRESSIVE PERSONALITY AND
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patients were enrolled; 38 were ran
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NRS7.2. THE USE OF THE MOOD DISORDE
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What were the missed opportunities
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compared with those without rapid c
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and poor control of impulsivity. Th
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tainty, which, in turn makes it pos
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they “did not want anyone to know
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the SOHO studies and followed up to
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occurring in the brain during REM s
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Page 176 and 177: PO1.56. RISPERIDONE AND HYPERPROLAC
Page 178 and 179: understanding and self-awareness (4
Page 180 and 181: five healthy subjects, genotyped fo
Page 182 and 183: patients and their relatives, the a
Page 184 and 185: PO1.86. VALACYCLOVIR-ASSOCIATED PSY
Page 186 and 187: effects of prenatal selective serot
Page 188 and 189: of these recovered patients, 10% re
Page 190 and 191: assess functional impairment. The F
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Page 196 and 197: PO1.130. ARIPIPRAZOLE IN ACUTE MANI
Page 198 and 199: in maintenance therapy could be the
Page 200 and 201: PO1.145. BIPOLAR DISORDER WITH A DE
Page 202 and 203: the Consort Statement guidelines. R
Page 204 and 205: for evaluation and a diagnosis of t
Page 206 and 207: PO1.170. EVALUATION OF LIOTHYRONINE
Page 208 and 209: only up to primary level education
Page 210 and 211: sistencies among magnetic resonance
Page 212 and 213: suppression of the immune system in
Page 214 and 215: isk factor unique to this populatio
Page 218 and 219: study we generated the stable MES23
Page 220 and 221: control group from the general popu
Page 222 and 223: PO2.14. AUGMENTATION WITH COGNITIVE
Page 224 and 225: PO2.22. FREQUENCY AND CLINICAL CORR
Page 226 and 227: CI -0.75; -0.14, p=0.004). In addit
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Page 230 and 231: PO2.46. CLINICAL HETEROGENEITY OF O
Page 232 and 233: studies are needed in order to iden
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Page 238 and 239: PO2.80. PERCEIVED FAMILY CONFLICTS
Page 240 and 241: PO2.88. BODY IMAGE IN A CLINICAL SA
Page 242 and 243: tions of self and others. These fea
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Page 248 and 249: PO2.120. DEMOGRAPHIC AND CLINICAL F
Page 250 and 251: jective scale, there was significan
Page 252 and 253: PO2.137. SURVEY OF AN ALCOHOL SUPPO
Page 254 and 255: PO2.145. PATHOLOGICAL GAMBLING IN P
Page 256 and 257: eceptor subtypes. To understand bet
Page 258 and 259: PO2.160. TYPOLOGY OF BEHAVIOR PROFI
Page 260 and 261: ADHD and 25 healthy controls were a
Page 262 and 263: PO3.10. METHYLPHENIDATE TRANSDERMAL
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PO3.26.2 IMPROVEMENTS IN MENTAL HEA
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health care settings to better meet
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children with or without MDD, and t
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shoulder pain unresponsive to non-s
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PO3.58. EFFICACY OF LAMOTRIGINE IN
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(mean 25.4-point change) and vitali
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PO3.74. PSYCHIATRIC COMORBIDITY IN
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in whom this type of intervention m
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PO3.91. EFFECTIVENESS OF PSYCHOEDUC
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ment choices. A 13-item questionnai
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onset of depression, patients with
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did not, also had poorer mental hea
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lized a comparison group, and exami
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PO3.133. PATTERNS OF CARE IN PATIEN
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PO3.140. DRUG NON-COMPLIANCE: THE I
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who were living part or full time w
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developed by a task force appointed
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lyzed using a modified grounded the
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PO3.174. THE EMILIA PROJECT: THE ST
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ecovered better from depression tha
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students of the Islamic Azad Univer
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individualized treatment plan, taki
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side effects), and reaching an effe
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models of circadian disturbances. M
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tinuous antipsychotic protection. T
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SPS9.5. IMPROVING CARDIOVASCULAR HE
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although preliminary, are promising
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INDEX OF AUTHORS Abbate A. 270 Abde
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Benítez-Hernández M.M. 297 Benito
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Centanaro F. 164 Cercignani M. 32 C
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Diez T. 164 Dimitrijevic I. 244 Din
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Gates D. 280 Gaviria S.L. 73 Gelao
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Hua-Min Xu 210 Huang H. 247 Huang J
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Kundi P.S. 257 Kunugi H. 248 Kupfer
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Marder S.R. 103 Margari F. 274, 275
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Napo F. 175 Narayana P.A. 76 Nardi
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Pieper S. 31 Pierantozzi E. 193 Pie
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Rybakowski J. 171 Ryder A.G. 138 Ry
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Stoduto G. 280 Stone M.H. 5, 38 Sto
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Villaseñor Bayardo S. 118 Vinberg
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ABSTRACTS - World Psychiatric Association

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