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ABSTRACTS - World Psychiatric Association

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PO1.22.<br />

ASSOCIATION BETWEEN DURATION<br />

OF UNTREATED PSYCHOSIS AND REMISSION<br />

IN SUBJECTS WITH SCHIZOPHRENIA<br />

OR SCHIZOAFFECTIVE DISORDER TREATED<br />

WITH LONG-ACTING INJECTABLE RISPERIDONE:<br />

A 52-WEEK ITALIAN STUDY<br />

G. Giardina, A. Rossi, M.G. Giustra, M.M. Bernareggi, on behalf<br />

of Risperidone Long-Acting Trial Italian Investigators<br />

Mental Health Department, Taranto; Department of Experimental<br />

Medicine, University of L’Aquila; Medical Affairs, Janssen-Cilag,<br />

Cologno Monzese, Milan, Italy<br />

The duration of untreated psychosis (DUP) is the time from the first<br />

psychotic symptom to initiation of treatment. A longer DUP leads to<br />

a poorer prognosis and a reduced likelihood of achieving remission.<br />

The objective of this analysis from an open label, single-arm 1-year<br />

trial with long-acting injectable risperidone (RLAI) was to investigate<br />

in a subset of subjects with different DUP which factors are predictors<br />

of remission. DUP was categorised in

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