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Wheat Amylase Trypsin Inhibitors as Divers of Innate Immunity in ...

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Characteristics and functions <strong>of</strong> cereal ATIs (2)<br />

• Up to 11 homologues <strong>in</strong> wheat (CM1-3, 16, 17,<br />

0.19, 0.28, 0.53……<br />

……)<br />

• Tetraploid encodes fewer than hxaploid wheat<br />

(lack <strong>of</strong> the D chromosome: : CM1, 3b, 7, 0.19, 0.28)<br />

• Pest control (<strong>in</strong>hibition<br />

<strong>of</strong> par<strong>as</strong>ite amyl<strong>as</strong>e and<br />

tryps<strong>in</strong> like activities)<br />

• Major wheat allergens (baker‘s <strong>as</strong>thma),<br />

food<br />

allergy to wheat and barley)<br />

Tatham and Shewry, Cl<strong>in</strong> Exp Allergy 2008

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