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AROUND THE QUADS<br />

COLUMBIA COLLEGE TODAY<br />

COLUMBIA COLLEGE TODAY<br />

AROUND THE QUADS<br />

Frances Champagne is an<br />

<strong>as</strong>sociate professor in the<br />

Department of Psychology<br />

focusing on behavioral neurosciences,<br />

maternal behavior<br />

and epigenetics. Born and<br />

raised in Canada, Champagne<br />

earned her undergraduate<br />

degree at Queen’s University,<br />

and her m<strong>as</strong>ter’s in psychiatry<br />

and Ph.D. in neuroscience<br />

at McGill University. She h<strong>as</strong><br />

been at <strong>Columbia</strong> since 2006<br />

and runs the Champagne Lab<br />

in psychobiology and neuroscience<br />

in addition to her<br />

professorial responsibilities.<br />

What drew you to<br />

psychology<br />

I always had an interest<br />

in it, probably more clinically<br />

oriented; I did a m<strong>as</strong>ter’s in<br />

psychiatry to explore that<br />

interest. I w<strong>as</strong> interested<br />

in schizophrenia and did a<br />

m<strong>as</strong>ter’s project looking at<br />

genetic and environmental<br />

factors and how they influence<br />

symptoms in schizophrenic<br />

individuals. I liked it<br />

but found I couldn’t <strong>as</strong>k the<br />

kind of mechanistic questions<br />

I w<strong>as</strong> interested in; it w<strong>as</strong> fine<br />

that these individuals had<br />

had these early experiences<br />

or traum<strong>as</strong> but I wanted to<br />

know more, in terms of how<br />

these experiences could lead<br />

to abnormal behaviors.<br />

How would you describe<br />

epigenetics to a layperson<br />

Epigenetics refers to the control<br />

of gene activity. We have<br />

our DNA but it h<strong>as</strong> to do<br />

something, it h<strong>as</strong> to produce<br />

something, to affect our biology.<br />

Epigenetics refers to the<br />

factors that can control that;<br />

the factors around DNA<br />

that can serve <strong>as</strong> kind<br />

of an on/off switch to<br />

gene activity. And then<br />

that gets laid into our<br />

biology and can l<strong>as</strong>t<br />

across the lifespan and<br />

lead to variations in<br />

stress reactivity, social<br />

behavior and reproductive<br />

behavior. … This work<br />

shows how the interplay between<br />

genes and the environment<br />

works. It brings people<br />

p<strong>as</strong>t the dichotomy of nature<br />

and nurture and moves them<br />

into something new.<br />

And what’s your interest<br />

within epigenetics<br />

I’m most interested in how<br />

early life experiences shape<br />

the brain, shape our behavior.<br />

For example, how toxins in<br />

the environment affect our<br />

behavior and might incre<strong>as</strong>e<br />

risk of psychopathology or<br />

health problems; how stress<br />

does the same thing; how<br />

mother-infant interactions can<br />

promote well-being or inhibit<br />

well-being. And then, what<br />

the long-term and multigenerational<br />

consequences are —<br />

meaning, the experiences you<br />

have during your life span<br />

shape you but they can also be<br />

p<strong>as</strong>sed along generations.<br />

What sort of work can undergraduates<br />

get involved with<br />

in your lab<br />

Quite a lot: For example, because<br />

we study mother/infant<br />

interactions, we have undergrads<br />

help with characterizing<br />

the mother/infant interactions<br />

in mice and rats. It’s hard to<br />

fit research around a cl<strong>as</strong>s<br />

schedule, and that’s something<br />

they can come in and<br />

do for an hour and then leave.<br />

We also have students looking<br />

at gene expression, taking<br />

brain t<strong>issue</strong> and analyzing<br />

what genes are incre<strong>as</strong>ed and<br />

decre<strong>as</strong>ed in their activity.<br />

We have students looking at<br />

different protein levels in the<br />

brain.<br />

What do you think students<br />

get out of working in a lab<br />

Five Minutes with ... Frances Champagne<br />

It’s fine to read about findings<br />

in papers but it’s quite<br />

another to be involved in the<br />

research and see how it’s actually<br />

done. I think it’s quite<br />

shocking at first — it’s a lot<br />

of work and it’s not always<br />

the most exciting work all the<br />

time. But it’s about the process<br />

of science. So I think they<br />

learn a lot.<br />

What do you teach<br />

I teach a big lecture course,<br />

“The Developing Brain,” and<br />

also two undergraduate seminars.<br />

I’ve been on maternity<br />

leave, though, and I just got<br />

back <strong>this</strong> p<strong>as</strong>t semester.<br />

What’s the most valuable<br />

thing a professor can do for<br />

his or her students<br />

Get them to appreciate how<br />

complex the process of science<br />

and the process of discovery<br />

is. You read textbooks<br />

and everything sounds so<br />

final and understood and<br />

clear — and something that’s<br />

hard to do in a lecture cl<strong>as</strong>s<br />

but that I can do in my<br />

seminar cl<strong>as</strong>ses, where I<br />

can interact with the students<br />

a bit more, is get<br />

them to critique the science<br />

that’s out there and<br />

realize that nothing’s<br />

perfect. That’s why we<br />

keep going with it, because<br />

we don’t have any final answers;<br />

there’s always something<br />

more to do or something<br />

that we can do better.<br />

So, I think in terms of pursuing<br />

a career in academia,<br />

that’s invaluable. Knowing<br />

that there are these weaknesses<br />

in all the work that’s done<br />

but that we can actually deal<br />

with that and do better.<br />

What’s your favorite place<br />

to be<br />

I go to York in Yorkshire, England,<br />

quite a lot; that’s where<br />

my husband [Assistant<br />

Professor of Psychology<br />

James Curley] is from.<br />

We met in Cambridge,<br />

actually, but York is an old<br />

city with so much history<br />

that you don’t get in North<br />

America.<br />

What’s a talent that you’d<br />

like to have<br />

To play the violin.<br />

If you weren’t a professor<br />

and a scientist, what would<br />

you like to do<br />

Probably run a small bookstore.<br />

It’d be nice to be<br />

somewhere surrounded by<br />

literature.<br />

What’s on your nightstand<br />

Baby books.<br />

How about your DVR Any<br />

guilty ple<strong>as</strong>ures<br />

Game of Thrones, which I can’t<br />

really watch right now because<br />

of the baby. Too violent.<br />

You said she’s your first<br />

Yes, Isabelle. She’s 14 months.<br />

So, does that mean you’ve<br />

started thinking about your<br />

research in relation to your<br />

own life<br />

Well, to some degree [laughs].<br />

But I also think there’s a risk<br />

of knowing too much and<br />

worrying too much. That’s<br />

one thing I know from work<br />

— it’s best not to be stressed.<br />

Interview: Alexis Tonti ’11 Arts<br />

Photo: Lynn Saville<br />

<strong>College</strong> Fetes<br />

Lit Hum at<br />

75 Years<br />

On April 26, alumni, parents<br />

and students gathered in<br />

Low Rotunda to celebrate<br />

“#LitHum75: Dialogues<br />

on the 75th Anniversary<br />

of Literature Humanities,” an event<br />

dedicated to the late Jacques Barzun ’27,<br />

’32 GSAS. The conversation began in<br />

Low Rotunda with introductions by<br />

Roosevelt Montás ’95, director of the<br />

Center for the Core Curriculum and<br />

<strong>as</strong>sociate dean of academic affairs, and<br />

Dean James J. Valentini, followed by a<br />

panel moderated by Gareth Williams,<br />

the Violin Family Professor of Cl<strong>as</strong>sics<br />

and chair of Literature Humanities.<br />

The panel featured Core faculty members<br />

James V. Mirollo ’61 GSAS, the<br />

Parr Professor Emeritus of English and<br />

Comparative Literature; Julie Crawford,<br />

<strong>as</strong>sociate professor of English and comparative<br />

literature; and Jessamyn Conrad,<br />

a Ph.D. candidate in the Department<br />

of Art History and Archaeology; <strong>as</strong> well<br />

<strong>as</strong> Huilong Han ’15 and Jacqueline Bryk<br />

’13. The dialogue focused on the way Lit<br />

Hum h<strong>as</strong> changed and its current relationship<br />

to the digital age.<br />

Immediately afterward, alumni and<br />

parents were invited to join students in<br />

cl<strong>as</strong>srooms across campus for seminarstyle<br />

discussion groups where attendees<br />

discussed either preselected works from<br />

the Lit Hum curriculum or their opinions<br />

about what they considered to be<br />

the most important part of the Core. This<br />

w<strong>as</strong> followed by a reception featuring<br />

remarks by Valentini and Edward Tayler,<br />

the Lionel Trilling Professor in the Humanities<br />

Emeritus, held in the Faculty<br />

Room in Low Library.<br />

Throughout the evening participants<br />

near and far were invited to join the conversation<br />

live and share Lit Hum memories<br />

by tweeting to #LitHum75.<br />

To explore the evening’s tweets, visit twitter.<br />

com/searchq=%23lithum75; to join the<br />

conversation, share your own memories by<br />

tweeting to #LitHum75.<br />

For more information about Literature<br />

Humanities’ 75 years at <strong>Columbia</strong>, visit<br />

college.columbia.edu/core/lithum.<br />

Four Alumni Honored with John Jay Awards<br />

PHOTO: EILEEN BARROSO<br />

Four accomplished alumni — Thom<strong>as</strong><br />

Cornacchia ’85; Katori Hall ’03; Mike<br />

Schmidtberger ’82, ’85L; and Dr.<br />

George Yancopoulos ’80, ’86 GSAS, ’87<br />

P&S — were presented with 2013 John<br />

Jay Awards for distinguished professional<br />

achievement on March 6 at Cipriani 42nd<br />

Street. Proceeds from the annual John<br />

Jay Awards Dinner benefit the John Jay<br />

National Scholars Program, which aims<br />

to enhance academic and extracurricular<br />

experiences for outstanding first-year<br />

<strong>College</strong> students. This year’s dinner raised<br />

$1.4 million.<br />

Above, Dean James J. Valentini (far left)<br />

joins the John Jay Scholars who presented<br />

the honorees with their awards, and the<br />

honorees, at the dinner. Left to right: Bryan<br />

Terraz<strong>as</strong> ’13; Cornacchia; Ethan Kogan ’13;<br />

Hall; Ariana Lott ’13; Schmidtberger; Yancopoulos;<br />

and Tehreem Rehman ’13.<br />

To read more about the dinner, see a<br />

Facebook photo album and view a video,<br />

visit college.columbia.edu/news/archive/<br />

2012-13.<br />

We’ve got you covered.<br />

Through <strong>Columbia</strong> Alumni Association,<br />

Group Term Life Insurance is available in<br />

amounts up to $1,000,000, underwritten<br />

by New York Life Insurance Company<br />

(NY, NY 10010), on Policy Form GMR.<br />

For details including features, costs, eligibility,<br />

renewability, limitations and exclusions, ple<strong>as</strong>e<br />

visit alumni.columbia.edu/alumni-discounts or<br />

call the plan administrator at 800-223-1147.<br />

or 12<br />

SUMMER 2013<br />

10<br />

SUMMER 2013<br />

11

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