Gene gain and loss: aCGH ISA CGH

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Gen etic Variation in h u m an gen om es From ch rom osom e an om alies to sin gle n u cleotid e ch an ges Chromosome <strong>Gene</strong> Nucleotide
CNV/ CNP Cop y n u m ber variation of DNA segm en ts ● ● ● Deletion s In sertion s Du p lication s Kb Mb b(nt)
Page 1: Gene gain and los s : aCGH ISA CGH
Page 5 and 6: 1. Clon es to cover a gen om ic reg
Page 7 and 8: Array CGH Adv antage ● An alysis
Page 9 and 10: ISA CGH ISACGH allows visualiz in g
Page 11 and 12: General outline INPUT: gen e exp re
Page 13 and 14: Genomic copy num ber es tim ation S
Page 15 and 16: Plotting data and copy num ber es t
Page 17 and 18: Minim al com m on regions w ith con
Page 19 and 20: Functional annotation of altered co
Page 21 and 22: An exam ple
Page 23 and 24: 2. CGH array data Ejem plo
Page 25 and 26: 4. Gender labels (optional) Ejem pl
Page 27 and 28: 6. Gene expression data Ejem plo
Page 29 and 30: 8. Scale value (optional) Ejem plo
Page 31 and 32: 9. Reference lines (optional) Ejem
Page 33 and 34: Ejem plo 10. If you have replicates
Page 35 and 36: Ejem plo 11. Choose the representat
Page 37 and 38: Ejem plo 13. Download data form reg
Page 39 and 40: Ejem plo 15. Zoom y functional anal
Page 41 and 42: Ejem plo 15. Zoom y functional anal
Page 43 and 44: http://gepas.bioinfo.cipf.es/cgib

Gene gain and loss: aCGH ISA CGH

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