E1™ Antioxidant Infused Technology - Biomet

E1
Antioxidant
Infused Technology
Knees • Hips • Extremities • Cement and Accessories • PMI ® • Technology

E1
Antioxidant Infused Technology
Infused with vitamin E, a natural
antioxidant, E1 Technology defines a
new class of bearings and overcomes
the limitations of remelted and annealed
polyethylenes by uniting true oxidative
stability, high mechanical strength and
ultra low wear. 1,2
Oxidative Stability
Testing has shown that vitamin E prevents
oxidative degradation of the polyethylene
without remelting, allowing the material to
maintain mechanical properties and wear
resistance over time. 1
0.8
Oxidation Profile 1,3
After ESC testing
0.7
Oxidation Index (Absorbance Units)
0.6
0.5
0.4
0.3
0.2
0.1
0.0
-0.1
Top
Surface
Center
Bottom
Surface
Sequentially Crosslinked and Annealed Loaded
Sequentially Crosslinked and Annealed Control
E1 Material Loaded
E1 Material Control
Mechanical Strength
E1 material is never remelted
and therefore maintains its strength. 1,2
It is also stronger than sequentially
crosslinked and annealed materials after
fatigue testing in an accelerated aging
environment (environmental stress
crack testing). 1
Ultra Low Wear
10 Mrad (100 kGy) irradiation results
in high levels of crosslinking for
wear resistance. 1
87 percent (posterior
stabilized) wear reduction
over conventional Direct
Compression Molded
polyethylene in the knee 1

Ultra Low Wear
50
Volumetric Wear Rates
of Largest Cruciate Retaining (CR)
Tibial Bearing Profile 1
Tested at Biomet Biomaterials Laboratory
43.4
40
89 percent wear reduction with
large heads when compared to
ArComXL ® Polyethylene in the hip 1
Volumetric Wear Rate
(mm 3 /MC)
30
20
86% CR wear
reduction
over Direct
Compression
Molded
10
6.1
0
DCM
UHMWPE
E1
Material
25
Volumetric Wear Rates
of Largest Posterior Stabilized (PS)
Tibial Bearing Profile 1
Tested at University of Nebraska
21.33
20
Volumetric Wear Rate
(mm 3 /MC)
15
10
5
87% PS wear
reduction
over Direct
Compression
Molded
2.87
0
DCM
UHMWPE
E1
Material
30
27.44
Volumetric Wear Rates
of 38mm Acetabular Liners 1
5 Million Cycles
38mm Head Size
25
Volumetric Wear Rate
(mm 3 /MC)
20
15
10
15.62
89% large
head wear
reduction over
ArComXL ®
Polyethylene
5
0
CoCr/ BIOLOX ®
ArComXL ® delta/
Polyethylene ArComXL ®
Polyethylene
3.16
CoCr/
E1
Material
1.71 1.37
BIOLOX ®
delta/
E1
Material
Metal-on-
Metal
(Run-in Wear)
1

E1 Technology and the Vanguard ® Complete Knee
E1 Tibial Bearings
Vanguard ® Complete Knee System
• Five primary articulations*
(see adjacent graphics)
• Patented 1:1 conformity in coronal plane:**
allows unlimited femoral/tibial sizing options
• Patellar tendon relief facilitates increased
range of motion
• Compressively loaded tibial locking
mechanism provides proven resistance
to tibial micromotion 4
* Articulation availability may vary by region. Please contact your
local Biomet Representative for details.
**U.S. Patent No. 5,330,534
Ultimate Tensile and Yield Strengths
for Multiple Polyethylenes 1,5
50
40
48.1
40.8
45.8
46.1
Tensile
Strength (MPa)
Yield
Strength (MPa)
Tensile Strength (MPa)
30
20
20.1
21.3
22.6
22.8
33.3
19.0
10
0
DCM Unaged 1 DCM Aged 1 E1
Material
Unaged 1
E1
Material
Aged 1
100kGy
Remelted 5
2

System
E1 Tibial
Bearing Options
Cruciate Retaining
• 3 degrees posterior slope
• 15 degrees internal/external rotation
Cruciate Retaining Lipped
• Enhanced posterior lip
• 15 degrees internal/external rotation
Anterior Stabilized
• Prominent 10mm anterior lip
• 5mm posterior lip
• 6 degrees internal/external rotation
Posterior Stabilized
• No varus/valgus constraint
• 15 degrees internal/external rotation
Posterior Stabilized Plus
• 2 degrees varus/valgus constraint
• +/- 2 degrees internal/external rotation
3

E1 Technology and the Taperloc ® Microplasty ® Hip
E1 Acetabular Liners
RingLoc ® + Modular Acetabular System
• Five liner configurations available from
28–40mm inner diameters
(see adjacent graphics)
• Can be used with large femoral heads for
optimal joint stability and range of motion
• BIOLOX ® delta ceramic heads on E1
bearings reduce wear by 46 percent over
cobalt chrome heads 1
Ultimate Tensile and Yield Strengths
for Multiple Polyethylenes 1,5–6
50
40
43
Tensile
Strength (MPa)
Yield
Strength (MPa)
Tensile Strength (MPa)
30
20
24.2
33
19
34
21
10
0
E1
Material 1
100kGy
Remelted 5
50kGy
Remelted 6
4

System
E1 Acetabular
Liner Options
Max-Rom + Liner
• Maximizes range of motion
• Allows for a 36mm head in a 50mm cup
Hi-Wall+ Liner
• Added lip offers additional joint stability
• Allows for a 36mm head in a 50mm cup
10-Degree Liner
• 10 degree angled face offers additional
joint stability
• Reduces the angle of a vertical liner
+5mm Hi-Wall Liner
• Added lip offers additional joint stability
• 5mm offset for joint restoration in
revision cases
+5mm Liner
• Maximizes range of motion
• 5mm offset for joint restoration in
revision cases

References
1. Data on file at Biomet. Bench test results not necessarily indicative
of clinical performance.
2. Kurtz, S. et al. The UHMWPE Handbook: Ultra High Molecular
Weight Polyethylene in Total Joint Replacement. Elsevier Academic
Press. San Diego, CA. 2004.
3. Nabar, S. et al. Comparison of Second Generation Highly Crosslinked
Polyethylenes Under Adverse Aging Conditions. ORS 2008. Poster
No. 1684.
4. Parks, N.L. et al. Modular Tibial Insert Micromotion: A Concern with
Contemporary Knee Implants. Clinical Orthopaedics and Related
Research. 356: 10–15, 1998.
5. Bhambri, S. et al. The Effect of Aging on Mechanical Properties
of Melt-annealed Highly Crosslinked UHMWPE. Crosslinked and
Thermally Treated Ultra-High Molecular Weight Polyethylene for
Joint Replacements. 171–82, 2004.
6. Greer, K.W. et al. The Effect of Raw Material, Irradiation Dose, and
Irradiation Source on Crosslinking of UHMWPE. Crosslinked and
Thermally Treated Ultra-High Molecular Weight Polyethylene for
Joint Replacements. 290–20, 2004.
BIOLOX ® delta is a trademark of CeramTec AG.
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otherwise indicated.
This material is intended for the sole use and benefit of the Biomet sales force and
physicians. It is not to be redistributed, duplicated or disclosed without the express
written consent of Biomet.
For product information, including indications, contraindications, warnings,
precautions and potential adverse effects, see the product-specific package inserts
and Biomet’s website.
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