Evaluation and Treatment of Diabetic Neuroarthropathy - Medical ...
Evaluation and Treatment of Diabetic Neuroarthropathy - Medical ...
Evaluation and Treatment of Diabetic Neuroarthropathy - Medical ...
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Neuropathy<br />
metabolic contribution:<br />
hyperglycemia results in: accumulation <strong>of</strong><br />
sorbitol; ↓ myo-inositol; conduction block<br />
<strong>of</strong> myelinated axons<br />
vascular contribution:<br />
extraneural A-V shunting; hypoxia<br />
narrowed capillary/arteriolar lumens<br />
poor regulation <strong>of</strong> microcirculation