Scientific Communication 14. Billings, N., M. Millan, M. Caldara, R. Rusconi, Y. Tarasova, R. Stocker, and K. Ribbeck. 2013. The extracellular matrix Component Psl provides fast-acting antibiotic defense in Pseudomonas aeruginosa biofilms. PLoS Pathog 9:e1003526. 15. Allesen-Holm, M., K. B. Barken, L. Yang, M. Klausen, J. S. Webb, S. Kjelleberg, S. Molin, M. Givskov, and T. Tolker-Nielsen. 2006. A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms. Mol. Microbiol. 59:1114-1128. 16. Chiang, W. C., M. Nilsson, P. Ø. Jensen, N. Høiby, T. E. Nielsen, M. Givskov, and T. Tolker-Nielsen. 2013. Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother. 17. Mulcahy, H., L. Charron-Mazenod, and S. Lewenza. 2008. Extracellular DNA chelates cations and induces antibiotic resistance in Pseudomonas aeruginosa biofilms. PLoS Pathog 4:e1000213. 18. Walker, T. S., K. L. Tomlin, G. S. Worthen, K. R. Poch, J. G. Lieber, M. T. Saavedra, M. B. Fessler, K. C. Malcolm, M. L. Vasil, and J. A. Nick. 2005. Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils. Infect. Immun. 73:3693-3701. 19. Chiang, W. C., M. Nilsson, P. O. Jensen, N. Hoiby, T. E. Nielsen, M. Givskov, and T. Tolker-Nielsen. 2013. Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother 57:2352-2361. 20. Purdy Drew, K. R., L. K. Sanders, Z. W. Culumber, O. Zribi, and G. C. Wong. 2009. Cationic amphiphiles increase activity of aminoglycoside antibiotic tobramycin in the presence of airway polyelectrolytes. J Am Chem Soc 131:486-493. 21. Pamp, S. J., M. Gjermansen, H. K. Johansen, and T. Tolker-Nielsen. 2008. Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes. Mol Microbiol 68:223-240. 22. Høiby, N. 2011. Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. BMC medicine 9:32. 23. Zimmerli, W., and C. Moser. 2012. Pathogenesis and treatment concepts of orthopaedic biofilm infections. FEMS Immunol Med Microbiol 65:158- 168. 24. Bjarnsholt, T., K. Kirketerp-Møller, S. Kristiansen, R. Phipps, A. K. Nielsen, P. Ø. Jensen, N. Høiby, and M. Givskov. 2007. Silver against Pseudomonas aeruginosa biofilms. APMIS 115:921-928. 25. Castellano, J. J., S. M. Shafii, F. Ko, G. Donate, T. E. Wright, R. J. Mannari, W. G. Payne, D. J. Smith, and M. C. Robson. 2007. Comparative evaluation of silver-containing antimicrobial dressings and drugs. Int Wound J 4:114-122. 26. Alhede, M., K. N. Kragh, K. Qvortrup, M. Allesen- Holm, M. van Gennip, L. D. Christensen, P. O. Jensen, A. K. Nielsen, M. Parsek, D. Wozniak, S. Molin, T. Tolker-Nielsen, N. Hoiby, M. Givskov, and T. Bjarnsholt. 2011. Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm. PLoS One 6:e27943. 27. Alhede, M., O. Er, S. Eickhardt, K. Kragh, M. Alhede, L. D. Christensen, S. S. Poulsen, M. Givskov, L. H. Christensen, N. Hoiby, M. Tvede, and T. Bjarnsholt. <strong>2014</strong>. Bacterial biofilm formation and treatment in soft tissue fillers. Pathogens and disease. 28. Nathan, C. 2006. Neutrophils and immunity: challenges and opportunities. Nature reviews. Immunology 6:173-182. 29. Bjarnsholt, T., M. Alhede, M. Alhede, S. R. Eickhardt-Sorensen, C. Moser, M. Kuhl, P. Ø. Jensen, and N. Høiby. 2013. The in vivo biofilm. Trends Microbiol 21:466-474. 30. Bjarnsholt, T., P. Ø. Jensen, M. Burmølle, M. Hentzer, J. A. Haagensen, H. P. Hougen, H. Calum, K. G. Madsen, C. Moser, S. Molin, N. Høiby, and M. Givskov. 2005. Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent. Microbiology 151:373-383. 31. Jensen, P. Ø., T. Bjarnsholt, R. Phipps, T. B. Rasmussen, H. Calum, L. Christoffersen, C. Moser, P. Williams, T. Pressler, M. Givskov, and N. Høiby. 2007. Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa. Microbiology 153:1329-1338. 32. Alhede, M., T. Bjarnsholt, M. Givskov, and M. Alhede. <strong>2014</strong>. Pseudomonas aeruginosa Biofilms: Mechanisms of Immune Evasion. Advances in applied microbiology 86:1-40. 33. Walker, T. S., K. L. Tomlin, G. S. Worthen, K. R. Poch, J. G. Lieber, M. T. Saavedra, M. B. Fessler, K. C. Malcolm, M. L. Vasil, and J. A. Nick. 2005. Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils. Infect Immun 73:3693-3701. 34. Gjodsbol, K., J. J. Christensen, T. Karlsmark, B. Jorgensen, B. M. Klein, and K. A. Krogfelt. 2006. Multiple bacterial species reside in chronic wounds: a longitudinal study. Int Wound J 3:225-231. 35. Bjarnsholt, T., K. Kirketerp-Møller, P. Ø. Jensen, K. G. Madsen, R. Phipps, K. Krogfelt, N. Høiby, and M. Givskov. 2008. Why chronic wounds will not heal: a novel hypothesis. Wound Repair Regen 16:2-10. 36. Hurlow, J., and P. G. Bowler. 2009. Clinical experience with wound biofilm and management: a case series. Ostomy Wound Manage 55:38-49. 37. Wolcott, R. D., and D. D. Rhoads. 2008. A study of biofilm-based wound management in subjects with critical limb ischaemia. J Wound Care 17:145-148, 150-142, 154-145. 38. Hall-Stoodley, L., P. Stoodley, S. Kathju, N. Hoiby, C. Moser, J. W. Costerton, A. Moter, and T. Bjarnsholt. 2012. Towards diagnostic guidelines for biofilm-associated infections. FEMS Immunol Med Microbiol 65:127-145. 39. Bjarnsholt, T., M. Alhede, M. Alhede, S. R. Eickhardt-Sorensen, C. Moser, M. Kuhl, P. O. Jensen, and N. Hoiby. 2013. The in vivo biofilm. Trends Microbiol. 40. Thomsen, T. R., M. S. Aasholm, V. B. Rudkjobing, A. M. Saunders, T. Bjarnsholt, M. Givskov, K. Kirketerp-Moller, and P. H. Nielsen. 2010. The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods. Wound Repair Regen 18:38-49. 41. Zandri, G., S. Pasquaroli, C. Vignaroli, S. Talevi, E. Manso, G. Donelli, and F. Biavasco. 2012. Detection of viable but non-culturable staphylococci in biofilms from central venous catheters negative on standard microbiological assays. Clin Microbiol Infect 18:E259-261. 42. Pasquaroli, S., G. Zandri, C. Vignaroli, C. Vuotto, G. Donelli, and F. Biavasco. 2013. Antibiotic pressure can induce the viable but non-culturable state in Staphylococcus aureus growing in biofilms. J Antimicrob Chemother 68:1812-1817. 43. Cutting, K. F. 2010. Addressing the challenge of wound cleansing in the modern era. Br J Nurs 19:S24, S26-29. 44. Rudkjobing, V. B., T. R. Thomsen, M. Alhede, K. N. Kragh, P. H. Nielsen, U. R. Johansen, M. Givskov, N. Hoiby, and T. Bjarnsholt. 2012. The microorganisms in chronically infected end-stage and non-endstage cystic fibrosis patients. FEMS immunology and medical microbiology 65:236-244. 45. Qian, Z., P. Stoodley, and W. G. Pitt. 1996. Effect of low-intensity ultrasound upon biofilm structure from confocal scanning laser microscopy observation. Biomaterials 17:1975-1980. 46. Qian, Z., R. D. Sagers, and W. G. Pitt. 1999. Investigation of the mechanism of the bioacoustic effect. J Biomed Mater Res 44:198-205. 47. Karau, M. J., K. E. Piper, J. M. Steckelberg, S. J. Kavros, and R. Patel. 2010. In vitro activity of the Qoustic Wound Therapy System against planktonic and biofilm bacteria. Advances in skin & wound care 23:316-320. 48. Dong, Y., S. Chen, Z. Wang, N. Peng, and J. Yu. 2013. Synergy of ultrasound microbubbles and vancomycin against Staphylococcus epidermidis biofilm. J Antimicrob Chemother 68:816-826. 49. Nishikori, T., M. Ochi, Y. Uchio, S. Maniwa, H. Kataoka, K. Kawasaki, K. Katsube, and M. Kuriwaka. 2002. Effects of low-intensity pulsed ultrasound on proliferation and chondroitin sulfate synthesis of cultured chondrocytes embedded in Atelocollagen gel. J Biomed Mater Res 59:201-206. 50. Nishikawa, T., A. Yoshida, A. Khanal, M. Habu, I. Yoshioka, K. Toyoshima, T. Takehara, T. Nishihara, K. Tachibana, and K. Tominaga. 2010. A study of the efficacy of ultrasonic waves in removing biofilms. Gerodontology 27:199-206. 51. Escandon, J., A. C. Vivas, R. Perez, R. Kirsner, and S. Davis. 2012. A prospective pilot study of ultrasound therapy effectiveness in refractory venous leg ulcers. Int Wound J 9:570-578. 52. Maher, S. F., J. Halverson, R. Misiewicz, T. Reckling, O. Smart, C. Benton, and D. Schoenherr. <strong>2014</strong>. Low-frequency Ultrasound for Patients With Lower Leg Ulcers Due to Chronic Venous Insufficiency: A Report of Two Cases. Ostomy Wound Manage 60:52-61. 53. Vicenti, F. A., J. L. Laus, J. M. Costa Neto, I. C. Talieri, C. F. Campos, A. T. Jorge, A. L. Ferreira, and A. P. Fantinatti. 2003. Effects of low-intensity pulsed ultrasound on wound healing in corneas of dogs following keratoplasty. Veterinary ophthalmology 6:255-263. 54. Hess, C. L., M. A. Howard, and C. E. Attinger. 2003. A review of mechanical adjuncts in wound healing: hydrotherapy, ultrasound, negative pressure therapy, hyperbaric oxygen, and electrostimulation. Annals of plastic surgery 51:210-218. 55. Butcher, G., and L. Pinnuck. 2013. Wound bed preparation: ultrasonic-assisted debridement. Br J Nurs 22:S36, S38-43. 56. Bexfield, A., A. E. Bond, E. C. Roberts, E. Dudley, Y. Nigam, S. Thomas, R. P. Newton, and N. A. Ratcliffe. 2008. The antibacterial activity against MRSA strains and other bacteria of a
BIOFILM COURSES <strong>2014</strong> m MADRID, SPAIN 13 MAY <strong>2014</strong> Full-day course in Biofilm Learning objectives: The importance of the bacterial biofilm mode of growth is becoming increasingly renowned as improved methods to study sessile bacteria have become available. The course will focus on the impact of biofilms in wounds, and implant associated areas, as well as addressing difficulties in diagnosis and treatment. Lectures: n Brief introduction to bacterial biofilm and its characteristics n Impact of biofilms in wounds and on implants n Pitfalls and guidelines in diagnosis of biofilm infections n Treatment strategies of biofilm infections in wounds and implants n Future treatment strategies m COPENHAGEN, DENMARK 4-5 JUNE <strong>2014</strong> 2nd practical course in Biofilm Procedures The biofilm course will introduce the participants to the topic of biofilm and its huge impact on chronic infections. Through lectures and a full day of hands on experiments, the participants will gain a vast understanding of biofilms and usable knowledge of how and why to implement biofilms into their research or product portfolio. The biofilm groups and the Biofilm Test Facility at the University of Copenhagen and Rigshospitalet have been investigating bacterial biofilms for 15 years and are regarded as leading pioneers in the field. FACULTY OF HEALTH AND MEDICAL SCIENCES UNIVERSITY OF COPENHAGEN For registration and more information on both courses, please see WWW.BIOFILMCOURSES.EU Contact Biofilm Course Secretariat: EWMA Secretariat/CAP Partner Nordre Fasanvej 113, 2. DK-2000 Frederiksberg Tel.: +45 70 20 03 05 info@cap-partner.eu
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BeneHold TASA The future of wound
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