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CCSP manual - BC Cancer Agency

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Appendix I<br />

Current <strong>BC</strong> <strong>Cancer</strong> <strong>Agency</strong> Guidelines for the<br />

Investigation and Management of Women with<br />

Screen Detected Abnormalities<br />

Low–Grade Epithelial Abnormalities<br />

Pap Smear Report Investigation Management<br />

Mild squamous dyskaryosis<br />

Mild endocervical glandular atypia<br />

Repeat smear at 6 month<br />

intervals for 2 years<br />

If abnormal cytology persists,<br />

refer to colposcopy<br />

If mild dysplasia (CIN 1)<br />

confirmed at colposcopy follow<br />

with repeat Pap in 6 months<br />

High-Grade Epithelial Abnormalities<br />

Pap Smear Report Investigation Management<br />

Moderate squamous dyskaryosis<br />

Marked squamous dyskaryosis<br />

Suspicious for squamous cell<br />

carcinoma in situ<br />

Malignant squamous cells<br />

Moderate endocervical glandular<br />

atypia<br />

Marked endocervical glandular<br />

atypia<br />

Cells suspicious for endocervical<br />

carcinoma seen<br />

Refer to colposcopy & directed<br />

biopsy<br />

• If moderate dysplasia/<br />

severe dysplasia/Ca in<br />

Situ, (CIN 2-3) confirmed,<br />

treatment by gynecologist<br />

with appropriate expertise<br />

• If microinvasion present,<br />

refer to gynecologist with<br />

appropriate expertise or<br />

gynecologic oncologist<br />

• If frank invasion present,<br />

refer to gynecologic<br />

oncologist at <strong>BC</strong>CA<br />

Malignant glandular cells seen<br />

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