Das Mittel Ihrer Wahl – Floxal

Das Mittel
Ihrer Wahl – Floxal ®
Bausch Bau Bausch ch + Lomb Lom Lombb Swiss SSwis
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AG, G, Dam Dammstrasse am a am ammst am mst ms mst mmst m mst ms st
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ras asse s 19, 119, CH-6301 Zug
Bausch + Lomb Swiss AG AG, CH CH-6301 6301 Zug
Floxal®/-UD. Zusammensetzung: Wirkstoff: Ofl oxacinum. Hilfsstoffe: Augentropfen, Fläschchen zu 5 ml: Conserv.: Benzalkonii chloridum; Excip. ad solutionem. Augentropfen, Unidosen (UD): Excip. ad
solutionem. Augensalbe: Adeps lanae; Excip. ad unguentum. Indikationen/Anwendungsmöglichkeiten: Behandlung bakterieller Infektionen des vorderen Augensegmentes und der Adnexe, wie Konjunktivitis,
Blepharitis und Blepharokonjunktivitis, welche durch empfindliche Keime hervorgerufen werden. Dosierung/Anwendung: Erwachsene: Augentropfen: 4xtgl. 1 Tropfen in den Bindehautsack
einträufeln. Die Dosierung kann je nach den pathologischen Gegebenheiten erhöht werden. Augensalbe: 3xtgl. einen 1 cm langen Salbenstrang in den Bindehautsack einbringen. Kinder und Jugendliche:
Die Dosierung bei Kindern unterscheidet sich nicht von der Erwachsener. Die Erfahrung bei Kindern ist allerdings begrenzt. Dosisfi ndungsstudien liegen nicht vor. Kontraindikationen: Überempfi ndlichkeit
gegenüber dem Wirkstoff oder einem der Hilfsstoffe (siehe «Zusammensetzung») oder gegen chemisch verwandte Chinolonderivate. Warnhinweise und Vorsichtsmassnahmen: Nicht anwenden bei Infektionen
mit Beteiligung der tieferen Augenstrukturen. Während der Behandlung mit Floxal ist unnötige Sonnen- oder Ultraviolettlicht-Exposition (z.B. Höhensonne, Solarium o.ä.) zu vermeiden (mögliche
Photosensibilität). Hinweise für Kontaklinsenträger: Bei bakteriellen Augeninfektionen sollen generell keine Kontaktlinsen getragen werden. Dies gilt auch für die Zeit der Anwendung von Floxal. Interaktionen:
Während der Behandlung mit Floxal sollten keine anderen Augenpräparate, die Schwermetalle (z.B. Zn) enthalten, verwendet werden, da mit einem Wirkungsverlust von Floxal zu rechnen ist.
Schwangerschaft/Stillzeit: Tierstudien haben dosisabhängige unerwünschte Effekte der oralen Anwendung von Ofloxacin auf die Föten gezeigt (Teratogenität). Es existieren jedoch keine kontrollierten
Humanstudien. Obwohl bei lokaler Anwendung keine Anhaltspunkte für eine fruchtschädigende Wirkung bestehen, und die täglich lokal applizierte Menge des Ofloxacins nur etwa 0.2% der therapeutisch
notwendigen oralen Dosis entspricht, soll die Anwendung während der Schwangerschaft und Stillzeit nur bei zwingender Indikation und unter Berücksichtigung der therapeutischen Alternativen erfolgen.
Unerwünschte Wirkungen: Augen: Gelegentlich vorübergehendes Stechen oder leichte Schmerzen nach Applikation. Lichtempfindlichkeit. Immunsystem: Gelegentlich, systemische anaphylaktische
Reaktion wie Asthma, Dyspnoe, Urticaria, Erythem, Pruritus sowie lokale Überempfi ndlichkeitsreaktionen. Allgemeine Störungen: Gelegentlich, Geruchs- und Geschmacksstörungen. Sonstige Hinweise:
Haltbarkeit: Das Arzneimittel darf nur bis zu dem auf der Packung mit «Exp» bezeichneten Datum verwendet werden. Floxal Augentropfen (Tropfflasche)/Floxal Augensalbe (Tube): Nach erstmaligem Öffnen
nicht länger als einen Monat verwenden. Floxal UD Unidosen: Für jede Anwendung einen neuen Behälter verwenden und diesen nach Gebrauch sofort wegwerfen. Besondere Lagerungshinweise: Bei
Raumtemperatur (15-25°C) aufbewahren. Augentropfen (Tropfflasche und Unidosen): Um die Augentropfen vor Licht zu schützen, sollen sie nach jeder Anwendung wieder in der Faltschachtel aufbewahrt
werden. Hinweise für die Handhabung: Um die Sterilität der Augentropfen/Augensalbe zu erhalten, Tropferspitze/Tubenspitze weder mit den Händen noch mit dem Auge berühren. Liste: A (Kassenzulässig)
Bausch & Lomb Swiss AG. Zulassungsinhaberin: Bausch & Lomb Swiss AG. Stand der Information: Juni 2006. Weitere Informationen entnehmen Sie bitte dem Arzneimittel-Kompendium der Schweiz

TABLE OF CONTENTS
Welcome from the Chairman, Co-Chairmen, Scientific Committee 4
Venue 5
General Information 5-7
Credit Allowances (CME credits) 6
Scientific Program – SSTED: Wednesday, December 8th 8
Thursday, December 9th 8
Friday, December 10th 10, 12
Saturday, Dec 11th 12, 14, 16
Scientific Program – SISAD: Wednesday, December 8th 9
Thursday, December 9th 9
Friday, December10th 11, 13
Saturday, December 11th 13, 15, 16
Patient Plenary Session Saturday, December 11 th 17
Social Program and Hotel Information 18
Index of Faculty 19
Acknowledgements of Sponsors, Exhibitors and Advertisers 23
Congress and
Event Center RONDO
Pontresina is located in a valley that branches off from the Upper Engadin, a unique alpine landscape.
It is a sunny place situated on a slope opening towards the southwest and with a wonderful
view of the mountains and glaciers. Pontresina continues to be a typical Engadin village,
embedded in dense woods of larch and stone pine trees. Do you know of a single conference
venue that sits atop an incomparable lake plateau, at the foot of a glacier, surrounded by an imposing
mountain panorama?
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WELCOME FROM THE CHAIRMAN
On behalf of the Co-Chairmen and members of the Scientific Committee I cordially invite you to
the 2nd Swiss Symposium on Thyroid Eye Disease (SSTED) from December 8 to 11, 2010
in Pontresina/St. Moritz. It is aimed at residents in training, fellows and clinicians from endocrinology
and ophthalmology, internists and general practitioners, being an educational clinical symposium
discussing mainly diagnostic and therapeutical issues of Graves’ orbitopathy.
On Saturday, Decemer 11, the Patient Plenary Session will be held at 13:30, answering the
most frequent questions encountered from interested patients with Graves’ orbitopathy. This session
will be videotaped and uploaded on our website (www.basedow.ch) after the symposium.
The SSTED is paralleled by a Special Interest Symposium on Autoimmune Disease (SISAD),
discussing mainly pathogenetic issues of autoimmune disease in general and its implications on
novel therapies of Graves’ orbitopathy in particular. The SISAD is aimed at basic and clinical scientists
in immunology, rheumatology, endocrinology and ophthalmology. Keynote lectures will be
given by key opinion leaders from different specialities, followed by ample discussions to engross
arising questions and controversies. For sustained impact, minutes of all sessions and discussions
will be distributed to the participants at the end of the symposium and be later published.
It is a special honor for the organizing committee, to host the faculty and executive committee of
the European Group on Graves’ Orbitopathy (EUGOGO), which will hold its scientific executive
meeting in Pontresina during our symposium. Its members are worldwide renowned experts
in the field and guarantee for outstanding lectures and discussions.
On behalf of the Scientific Committee, I would like to warmly welcome all participants, particularly
all our lecturers and colleagues from EUGOGO in the highest-altitude conference centre in Europe,
hopefully with lots of snow and a few sunny days.
George F. von Arx, Symposium Chairman
Co-Chairmen:
Beat Hammer, Hirslanden Medical Center,
Aarau
Jürg Lareida, Aarau
Scientific Committee:
Marian Ludgate, University of Cardiff, UK
(Chair)
Rebecca S Bahn, Mayo Clinic, Rochester, MN,
USA (Co-Chair)
J. Paul Banga, King’s College, London, UK
Ulrich Bürgi, University Hospital Berne, CH
Mario Salvi, University of Milan, IT
Matthias Stahl, Kantonsspital Olten, CH
Alan Tyndall, University of Basel, CH

Venue
Congress and Event Center RONDO
CH-7504 Pontresina/Switzerland
Ph +41 (0)81 838 83 12
Fax +41 (0)81 838 83 10
Opening hours of registration desk
Wednesday, Dec. 8 th (10:00 – 18:00)
Thursday, Dec. 9 th (12:00 – 17:30)
Friday, Dec. 10 th (08:00 – 17:15)
Saturday, Dec. 11 th (08:00 – 15:00)
Dates SSTED
Thursday, Dec. 9 th (14:00 – 18:00)
Friday, Dec. 10 th (09:00 – 18:00)
Saturday, Dec. 11 th (09:00 – 15:00)
Dates SISAD
Thursday, Dec. 9 th (14:00 – 18:00)
Friday, Dec. 10 th (09:00 – 18:00)
Saturday, Dec. 11 th (09:00 – 15:00)
EUGOGO Executive Meeting
Wednesday, Dec. 8 th (14:00 – 18:00)
Thursday, Dec. 9 th (08:00 – 13:00)
Official Language: English
Scientific Secretariat
George F. von Arx
basedow.ch – Interdisciplinary
Center for Thyroid Eye Disease
ADMEDICO Orbital Center
Fährweg 10, CH-4600 Olten
Ph +41 (0)62 206 87 37
Fax +41 (0)62 206 87 38
georg.vonarx@admedico.ch
Central Organization/Administration
Meister ConCept GmbH
Bahnhofstrasse 55, CH-5001 Aarau
Ph +41 (0)62 836 20 90
Fax +41 (0)62 836 20 97
meister@meister-concept.ch
GENERAL INFORMATION
Registration
Online: www.basedow.ch
The registration will automatically be
confirmed by Email.
Registration is possible until November 28,
2010 or on-site. For reduced fees however
please register before October 31, 2010.
Registration Fees
Early Bird until October 31 st
Participants CHF 550.00
Residents 1) CHF 450.00
Regular until December 11 th
Participants CHF 650.00
Residents 1) CHF 550.00
Official Opening Ceremony free of charge
(we kindly ask you to register)
Registration fee includes: symposium
documents, admission to all sessions, coffee
breaks, lunches, get-together party
1) A certificate of the head of the department is mandatory
Social Events
Gala Dinner at the Hotel Saratz CHF 90.00
Residents 1) CHF 70.00
Payment
Payment is accepted in Swiss Francs only.
Online by credit card or by bank transfer to:
Aargauische Kantonalbank
CH-4600 Olten
IBAN: CH69 0076 1016 1127 7578 9
Beneficiary:
ADMEDICO Augenzentrum GmbH
basedow.ch, Fährweg 10
CH-4600 Olten
All bank fees must be paid by the participants
and will not be covered by the beneficiary.
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GENERAL INFORMATION
Cancellation
Cancellation of registration: written notification
to the Central Organizer. No refund of registration
fee.
Disclaimer
The Symposium and the Central Organizer
cannot accept any liability for the acts of any
supplier to the symposium or the safety of any
attendee while in transit to or from the event. All
participants are strongly advised to carry the
proper travel and health insurance as the symposium
and the Central Organizer cannot accept
liability for any accidents or injuries that
may occur.
Hotel Accommodation
Online reservation can be made until October
15, 2010 at www.basedow.ch, under 2 nd
Swiss Symposium on Thyroid Eye Disease →
Hotelreservation, or by down-loading the form.
An adequate number of rooms has been
blocked and special rates have been obtained
to your advantage.
The congress is not responsible for no shows
or cancellation fees.
Meals
Coffee breaks and lunches will be served during
the intermission in the exhibition area and
are included in the registration fee.
Industrial Exhibition
The industrial exhibition is an integral part of the
symposium. It will be open every day throughout
the meeting.
Credit Allowance
CME certificates will be handed out at the registration
desk.
The Symposium is accredited by the following
societies with an estimated credit amount of
the following:
American Medical Association
AMA: 13 credits
European Accreditation Council for
Continuing Medical Education
EACCME and
European Union of Medical Specialists
UEMS: 13 credits
Swiss Society of Endocrinology and
Diabetology
SGED: 13 credits
Swiss Society of General Internal Medicine
SGIM: 16.5 credits
Swiss Society of General Medicine
SGAM: fully accredited
Swiss Society of Ophthalmology
SOG 13 credits
Technical aspects/presentations
Authors are requested to deliver their Power-
Point presentations on a USB stick or CD at
the registration desk at least 1 hour prior to
their presentation in order to check with the
technical support.

Traveling by Rail
Arriving at Zurich International airport as well as
from all other destinations you first travel to
Chur by Swiss Rail (SBB/CFF). In Chur, board
one of Rhaetian Railway's state-of-the art fast
trains to take you through curving tunnels and
across breathtaking bridges. To make your
train journey even more comfortable, use the
combined air-and-rail baggage service.
The trip from Zurich to Pontresina will take
about 3 hours.
Milan – Pontresina 175 Km 3hrs
Munich – Pontresina 300Km 4hrs
Basel – Pontresina 250Km 4hrs
Traveling by Air
We strongly recommend to fly to Zurich International
Airport, but there are services from international
airports to Samedan/St. Moritz and
air-taxi connections to many other national and
international destinations.
The regional Airport, operated by Engadin Airport,
lies in Samedan, 4km from Pontresina at
a height of 1707 meters above sea level. It is
the highest airport in Europe.
Engadin Airport, CH-7503 Samedan
Ph +41 (0)81 851 08 51
info@engadin-airport.ch
www.engadin-airport.ch
Car Rentals
Avis Autovermietung AG, 8048 Zürich
Ph +41 (0) 848 81 18 18
Fax +41 (0) 848 81 18 04
reservations@avis.ch
Hertz AG, 8004 Zürich
Ph +41 (0)848 82 20 25
Fax +41 (0)44 242 25 86
www.hertz.ch
GENERAL INFORMATION
Taxis
A taxi will bring you directly to your desired
destination, day- and night time.
Taxi Bernina, CH-7504 Pontresina
Ph +41 (0)79 786 19 17
Pontresina Tourist Information
CH-7504 Pontresina
Ph +41 (0)81 838 83 00
Fax +41 (0)81 838 83 10
www.engadin.stmoritz.ch/mice
Skiing and leisure
Would you like to combine your educational
stay in Switzerland with a few leisure days in
the beautiful area of Pontresina/Engadine?
Hotels offer the same room rates for prolongation
of your stay. Advantageous rates for skitickets
are available as well.
The Sporthotel Pontresina offers
Ski & Snowboard Specials.
The Hotel Saratz offers
a «Winterpackage First Snow.»
Please contact:
Engadin St. Moritz
Via San Gian 30
CH-7500 St. Moritz
Ph +41 (0)81 830 00 01
Fax +41 (0)81 830 08 18
allegra@estm.ch
www.engadin.stmoritz.ch/ferien
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SCIENTIFIC PROGRAM
2ND SWISS SYMPOSIUM ON THYROID EYE DISEASE – SSTED
SELA ARABELLA
WEDNESDAY, DECEMBER 8, 2010
14:00 EUGOGO Executive Meeting I (Hotel Saratz)
20:00 Dinner at the Hotel Saratz
THURSDAY, DECEMBER 9, 2010
08:00 EUGOGO Executive Meeting II (Hotel Saratz)
14:00 Opening Ceremony & Introduction
George F. von Arx, Symposium Chairman, Olten, Switzerland
Petros Perros, Newcastle upon Tyne, United Kingdom
Session I
14:15 Basics in Graves’ Disease for Ophthalmologists, General Practitioners & Residents
Matthias Stahl, Olten, Switzerland
15:00 Basics in Graves’ Orbitopathy for Endocrinologists, General Practitioners & Residents
Nicole Fichter, Olten, Switzerland
15:45 Coffee Break
16:30 Quality of Life & Social Impact on Health Systems
Susanne Pitz, Mainz, Germany
17:00 Motility Restrictions in GO: Impact on Quality of Life & Treatment
Anja Eckstein, Essen, Germany
17:30 Round Table: GO – Focus on the Essential!
Chair: James A. Garrity, Rochester, MN, United States of America
18:00 Get Together Party

SCIENTIFIC PROGRAM
SISAD – SPECIAL INTEREST SYMPOSIUM ON AUTOIMMUNE DISEASE
SELA PULCINELLA
WEDNESDAY, DECEMBER 8, 2010
14:00 EUGOGO Executive Meeting I (Hotel Saratz)
20:00 Dinner at the Hotel Saratz
THURSDAY, DECEMBER 9, 2010
08:00 EUGOGO Executive Meeting II (Hotel Saratz)
14:00 Opening Ceremony & Introduction
Marian Ludgate, Cardiff, United Kingdom
Rebecca S. Bahn, Rochester, MN, United States of America
Session I
14:10 Disease Markers
Introduction & Chair: Rebecca S. Bahn, Rochester, MN, United States of America
14:15 Antibodies in Autoimmune Disease with special emphasis on TSH-Antibodies in GO
Matthias Schott, Düsseldorf, Germany
14:50 Role of the T-Cell in the Eye Muscle Component of Thyroid Eye Disease
Jack Wall, Penrith, NSW, Australia
15:15 Discussion
15:45 Coffee Break
16:30 Antigen Specific Therapies
Introduction & Chair: Marian Ludgate, Cardiff, United Kingdom
16:35 Interaction of the TSH-Receptor with Auto-Antibodies: New Prospects for Treatment
Jane Sanders, Cardiff, United Kingdom
17:15 Discussion
18:00 Get Together Party
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10
SCIENTIFIC PROGRAM
2ND SWISS SYMPOSIUM ON THYROID EYE DISEASE – SSTED
SELA ARABELLA
FRIDAY, DECEMBER 10, 2010
Session II
Assessment of Patients with GO, Part I
09:00 Assessment of Patients with GO, Introduction
Jane Dickinson, Newcastle upon Tyne, United Kingdom
09:20 Assessment of Disease Activity and Severity
Carol Lane, Cardiff, United Kingdom
09:40 Standardized Orthoptic Assessment as proposed by EUGOGO
Hinke-M. Jellema, Amsterdam, The Netherlands
10:10 Imaging in GO – MRI-TIRM: The basedow.ch Pilot Study
Eberhard Kirsch, Aarau, Switzerland
10:30 Orbital Fat and Muscle Volume Measurements in GO
Wilmar Wiersinga, Amsterdam, The Netherlands
11:00 Round Table: What is the State of the Art in Assessing Patients with GO?
Chair: Maarten Mourits, Amsterdam, The Netherlands
11:30 Lunch
Session III
Assessment of Patients with GO, Part II
12:30 Optic Nerve Involvement – Dysthyroid Optic Neuropathy (DON)
Antonella Boschi, Brussels, Belgium
12:50 Color Contrast Sensitivity Testing – A Useful Tool in Diagnosing DON?
Nicole Fichter, Olten, Switzerland
13:10 Graves’ Orbitopathy & Glaucoma
Ivan Haefliger, Basel, Switzerland
13:30 Differential Diagnosis of Graves’ Orbitopathy
Maarten Mourits, Amsterdam, The Netherlands
13:50 Lecture in Honor of Prof. Wilmar Wiersinga
Achievements & Perspectives in GO
Luigi Bartalena, Varese, Italy

SCIENTIFIC PROGRAM
SISAD – SPECIAL INTEREST SYMPOSIUM ON AUTOIMMUNE DISEASE
SELA PULCINELLA
FRIDAY, DECEMBER 10, 2010
Session II
09:00 Animal Models
Introduction & Chair: Rebecca S. Bahn, Rochester, MN, United States of America
09:05 Evidence of Orbital Involvement in Graves’ Disease Animal Models using
Immunization against the TSH-Receptor
Anja Eckstein, Essen, Germany
09:45 State of the Art Animal Models of Graves’ Disease: A Novel Murine Model of GO
J. Paul Banga, London, United Kingdom
10:30 Discussion
11:30 Lunch
Session III
12:30 Innate Immunity & Commensal Infection
Introduction & Chair: Marian Ludgate, Cardiff, United Kingdom
12:35 Microbial Influences in Autoimmunity – Pathogens versus Commensals
Susan F. Wong, Bristol, United Kingdom
13:15 Discussion
13:50 Lecture in Honor of Prof. Wilmar Wiersinga
Achievements & Perspectives in GO
Luigi Bartalena, Varese, Italy
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SCIENTIFIC PROGRAM
2ND SWISS SYMPOSIUM ON THYROID EYE DISEASE – SSTED
SELA ARABELLA
FRIDAY, DECEMBER 10, 2010
14:50 Compliments by Mrs. Barbara Janom Steiner, Chur, Switzerland
State Councillor and Head of the Department of Justice, Health and Safety
15:00 Coffee Break
Session IV
Treatment of Graves’ Disease
15:30 Treatment Concepts in Graves’ Disease
Laszlo Hegedüs, Odense, Denmark
16:00 Antithyroid Drugs – Titration versus Block & Replace Therapy?
John Lazarus, Cardiff, United Kingdom
16:25 Radioiodine – Do’s and Don’ts in Clinical Practice
Hans C. Steinert, Zürich, Switzerland
16:50 Thyroidectomy and Radioiodine – The Concept of Total Thyroid Ablation
Claudio Marcocci, Pisa, Italy
17:15 Round Table: Is there a «Best Treatment?»
Chair: Gerasimos Krassas, Thessaloniki, Greece
20:00 Gala Dinner at the Hotel Saratz
SATURDAY, DECEMBER 11, 2010
Session V
Medical Treatment of Graves’ Orbitopathy
09:00 Pathogenesis and General Concepts
Terry J. Smith, Ann Arbor, MI, United States of America
09:30 Steroids – The Irreplaceables!
Petros Perros, Newcastle upon Tyne, United Kingdom
10:00 Selenium – Results of the EUGOGO Multicenter Study
Claudio Marcocci, Pisa, Italy

SCIENTIFIC PROGRAM
SISAD – SPECIAL INTEREST SYMPOSIUM ON AUTOIMMUNE DISEASE
SELA PULCINELLA
FRIDAY, DECEMBER 10, 2010
14:50 Compliments by Mrs. Barbara Janom Steiner, Chur, Switzerland
State Councillor and Head of the Department of Justice, Health and Safety
15:00 Coffee Break
Session IV
15:30 Genetics
Introduction & Chair: Marian Ludgate, Cardiff, United Kingdom
15:35 Advances in the Genetics of Autoimmunity: Have these translated back to the Clinic?
Simon Pearce, Newcastle upon Tyne, United Kingdom
16:05 Discussion
16:30 Epigenetics
Introduction & Chair: Wilmar Wiersinga, Amsterdam, The Netherlands
16:35 Epigenetics in Autoimmunity
Steffen Gay, Zürich, Switzerland
17:15 Discussion
20:00 Gala Dinner at the Hotel Saratz
SATURDAY, DECEMBER 11, 2010
Session V
09:00 Dendritic Cells
Introduction & Chair: Jacques Orgiazzi, Lyon, France
09:05 An Overview of Molecular & Cellular Pathways in Organ-Specific Autoimmunity,
Possibility of Drug Targeting
Hemmo A. Drexhage, Rotterdam, The Netherlands
09:50 Discussion
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SCIENTIFIC PROGRAM
2ND SWISS SYMPOSIUM ON THYROID EYE DISEASE – SSTED
SELA ARABELLA
SATURDAY, DECEMBER 11, 2010
10:30 Novel Therapies – The Mayo Clinic Experience
Rebecca S. Bahn, Rochester, MN, United States of America
11:00 Round Table: Should we treat the Orbit or the Underlying Systemic Autoimmune Disease?
Chair: Mario Salvi, Milano, Italy
11:30 Coffee Break
Session VI
Surgical Treatment of Graves’ Orbitopathy
12:00 General Concepts, Introduction
Peter Dolman, Vancouver, BC, Canada
12:20 Individualized, Anatomy Based Surgical Concepts for Orbital Decompression –
Results of the AO Trial
Beat Hammer, Aarau, Switzerland
12:40 Orbital Decompression – Does one fit all?
James A. Garrity, Rochester, MN, United States of America
12:55 Fat Decompression – Alternative or Amendment to Bony Decompression?
Michael Kazim, New York City, NY, United States of America
13:10 Lateral Wall Decompression
Rudolf Guthoff, Rostock, Germany
William Katowitz, Philadelphia, PA, United States of America
13:30 Squint Surgery
Michael Schittkowski, Göttingen, Germany
13:45 Lid Surgery in GO – Functional versus Aesthetic Lid Surgery
Kostas Boboridis, Thessaloniki, Greece
14:05 Round Table: Functional – Cosmetic – Rehabilitative Surgery
Chairs: Lelio Baldeschi, Pisa, Italy
James A. Garrity, Rochester, MN, United States of Amercia

SCIENTIFIC PROGRAM
SISAD – SPECIAL INTEREST SYMPOSIUM ON AUTOIMMUNE DISEASE
SELA PULCINELLA
SATURDAY, DECEMBER 11, 2010
10:20 B-Cells
Introduction & Chair: Alan Tyndall, Basel, Switzerland
10:25 B-Cell Function and Depletion in Autoimmune Disease
Peter M. Villiger, Bern, Switzerland
11:15 Discussion
11:30 Coffee Break
Session VI
12:00 Stem Cells
Introduction & Chair: Terry J. Smith, Ann Arbor, MI, United States of America
12:05 Ablation and Reconstitution of the Immune System in Autoimmune Disease by
Mesenchymal Stem Cells?
Alan Tyndall, Basel, Switzerland
12:50 Discussion
13:20 New Treatment Modalities – Biologics: Are they safe?
Introduction & Chair: Mario Salvi, Milano, Italy
13:40 Pros & Cons of Novel Therapies
Laszlo Hegedüs, Odense, Denmark
14:10 Discussion
15

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2ND SWISS SYMPOSIUM ON THYROID EYE DISEASE – SSTED
SISAD – SPECIAL INTEREST SYMPOSIUM ON AUTOIMMUNE DISEASE
SATURDAY, DECEMBER 11, 2010
14:30 Summary and Closing Ceremony
∙ What did we learn about GO and its management?
∙ Is there a change in paradigms since the 1 st SSTED in 2007?
∙ What are the future perspectives in the management of GO?
Petros Perros, EUGOGO Chairman, Newcastle upon Tyne, United Kingdom
Marian Ludgate, Cardiff, United Kingdom
Rebecca S. Bahn, Rochester, MN, United States of America
Maarten Mourits, Amsterdam, The Netherlands
Beat Hammer, Aarau, Switzerland
Final statement by a Graves’ Orbitopathy patient
14:45 Farewell & Announcement of the 3 rd SSTED/SISAD from December 4 to 7, 2013
George F. von Arx, Symposium Chairman, Olten, Switzerland
See you in Pontresina 2013!
Schneeschuhwanderer im Morteratsch (Pontresina-Engadin). Dezember 2008, Fotograf: Christoph Sonderegger, St. Gallen, Copyright: Pontresina Tourismus

PATIENT PLENARY SESSION
SATURDAY, DECEMBER 11, 2010
13:00 Open Forum for Patients with Graves’ Disease/Graves’ Orbitopathy
Terry J. Smith, Ann Arbor, MI, United States of Amercia
George F. von Arx, Symposium Chairman, Olten Switzerland
Dear Patients
As the symposium chairman I would like to warmly invite you to your Patient Plenary Session in
the beautiful Engadin valley.
It is our aim to provide a special forum for patients amidst an international symposium with the
world's most renowned, medical and scientific experts in Graves' Orbitopathy.
The discussions will be recorded and uploaded to the website after the symposium.
Key opinion leaders from medical centres and clinics from all around the world will meet patients
with Graves' Disease/Graves' Orbitopathy to discuss and answer your questions.
The entrance to the Patient Plenary Session is free for all to attend.
For patients who wish to participate in the entire symposium, please register online
(www.basedow.ch) as a resident at the early bird rate of CHF 450.00. Special symposium flat
rates are provided for your accomodation in the Pontresina Symposium Hotels.
For more information, travel and accommodation assistance please refer to our homepage
www.basedow.ch or mail to the central organization and administration office.
George F. von Arx, Symposium Chairman
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SOCIAL PROGRAM AND HOTEL INFORMATION
Get-Together Party
Thursday, December 9, at 18:00. Meeting point: Symposium Venue
Gala Dinner
Friday, December 10, at 20:00 at the Hotel Saratz
YOUR HOSTS IN PONTRESINA
Welcome to the Hotel Saratz
The 4-star-superior Hotel Saratz in Pontresina is elegant yet informal,
modern yet charming – and its blend of old and new
exudes one thing above all else: atmosphere. Here, a contemporary
lifestyle merges with Engadin hotel tradition, grandezza
with design, nature with architecture. Experience a holiday in
unique surroundings in the midst of the Engadin mountain
world. www.saratz.ch
The Sporthotel Pontresina is located in the heart of Pontresina.
Our friendly atmosphere with a smile and the personal service
as well as our additional services underline our standard.
The renovated bed-rooms are bright and friendly (bath or shower
and toilet, Sat-TV, radio, phone). The wellness oasis above
the roofs of Pontresina with marvelous view into the valley Rosegg
offers a great opportunity to relax. Or enjoy the sun on our
terrace.
www.sporthotel.ch
FRANKREICH
Genf (480 km)
Basel (290 km)
DEUTSCHLAND
Frankfurt (590 km)
Schaffhausen
Landquart
Bern (330 km)
Davos
Disentis
Chur
Zernez
Filisur
Andermatt
Thusis
Samedan
St. Moritz Pontresina
ENGADIN
Mals
Brig
Poschiavo
Chiavenna
Tirano
Zermatt
Arrival from Airports
Glacier Express
Bernina Express
UNESCO-Welterbe Albula/Bernina
Venedig – St. Moritz Tour
Palm Express (BusTrail)
ITALIEN
Lugano (125 km)
Lecco
München (300 km)
Friederichshafen (210 km)
Zürich (200 km)
ÖSTERREICH
St. Gallen (190 km)
Innsbruck (190 km)
ITALIEN
Meran
Bozen
Trento
Bergamo (145 km)
Mailand (175 km) Verona
Vicenza
Padova
Venedig
Copyright: Pontresina Tourismus

INDEX OF FACULTY
Bahn Rebecca S. Prof., Mayo Clinic, College of Medicine, Department of
Endocrinology, 200 First Street S.W., Rochester, MN, 55905,
United States of America
Baldeschi Lelio M.D., Via Putignano 315/C, 56100 Pisa, Italy
Banga J. Paul Prof., King’s College, School of Medicine, Department of Diabetes
and Endocrinology, The Rayne Institute, Denmark Hill Campus,
SE5, 9NU London, United Kingdom
Bartalena Luigi Prof., Dipartimento di Medicina Clinica, Endocrinologia,
Via O. Rossi 9, 2100 Varese, Italy
Boboridis Kostas MD, Phd, Panagia General Hospital, Department of Ophthalmology,
Orbita Unit, N. Plasira 22, 551 32 Thessaloniki, Greece
Boschi Antonella Dr., Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10,
1200 Brussels, Belgium
Bürgi Ulrich Prof. Dr. med., Inselspital Bern, Klinik und Poliklinik für Allgemeine Innere
Medizin, 3010 Bern, Switzerland
Dickinson Jane Prof., The Newcastle upon Tyne Hospitals NHS Foundation Trust,
Ophthalmology Department, Royal Victoria Infirmary, Queen
Victoria Road, NE1 4LP Newcastle upon Tyne, United Kingdom
Dolman Peter Prof., University of British Columbia, Department of Ophthalmology,
2550 Willow Street, Vancouver, BC, V5Z 3N9 Canada
Drexhage Hemmo A. M.D., Erasmus University Rotterdam, Department of Immunology,
Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
Eckstein Anja Prof. Dr. med., Universitätsklinikum Essen,
Zentrum für Augenheilkunde, Orbitazentrum, Hufelandstrasse 55,
45147 Essen, Germany
Fichter Nicole Dr. med., ADMEDICO Augenzentrum, basedow.ch – Interdisziplinäres
Zentrum für Endokrine Orbitopathie, Fachärztin FMH, Okuloplastische,
Rekonstruktive und Orbitachirurgie, Fährweg 10, 4600 Olten, Switzerland
Garrity James A. Prof., Mayo Graduate School of Medicine, Mayo Clinic,
Department of Ophthalmology, 200 First Street S.W., Rochester,
MN, 55905, United States of America
19

20
INDEX OF FACULTY
Gay Steffen Prof. Dr. med., Universitätsspital Zürich, Rheumaklinik & Physikalische
Medizin, Gloriastrasse 25, 8091 Zürich, Switzerland
Guthoff Rudolf Prof. Dr. med., Universitätsaugenklinik Rostock, Doberaner Strasse 140,
18057 Rostock, Germany
Haefliger Ivan Prof. Dr. med., Merian Iselin Spital, Augenabteilung,
Leimenstrasse 76, 4051 Basel, Switzerland
Hammer Beat Prof. Dr. med., Facharzt FMH für Gesichts- und Kieferchirugie,
Hirslanden Medical Center, Rain 34, 5000 Aarau, Switzerland
Hegedüs Laszlo M.D., D.M.Sc., Odense University Hospital, Department of
Endocrinology and Metabolism, 5000 Odense C, Denmark
Jellema Hinke-M. PhD., Universiteit van Amsterdam, Academisch Medisch Centrum,
Orbita Centrum, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Katowitz William Prof., Children’s Hospital of Philadelphia, Ophthalmology, Orbital Unit,
324 S34th Street, Philadelphia, PA, 19104, United States of America
Kazim Michael Prof., Columbia-Presbyterian Medical Center, Edward S. Harkness
Eye Institute, Dept. of Ophthalmology, 635 West 165th Street,
New York City, NY, United States of America
Kirsch Eberhard PD Dr. med., Hirslanden Klinik, Institut für Radiologie,
Schänisweg, 5000 Aarau, Switzerland
Krassas Gerasimos Prof., Panagia General Hospital, Department of Endocrinology,
N. Plasira 22, 55132 Thessaloniki, Greece
Lane Carol Prof., University Hospital of Wales, Cardiff Eye Unit, Oculoplastic,
Reconstructive and Orbital Surgeon, Heath Park 144, Cardiff,
United Kingdom
Lareida Jürg Dr. med., Facharzt FMH für Innere Medizin, speziell Endokrinologie,
Vordere Vorstadt 16, 5000 Aarau, Switzerland
Lazarus John Prof., Cardiff University, Centre for Endocrine & Diabetes Sciences,
CF14 4XN Cardiff, United Kingdom

INDEX OF FACULTY
Ludgate Marian Prof., Cardiff University, Main Building School of Medicine, Centre
for Endocrine & Diabetes Sciences, Heath Park, CF14 4XN Cardiff,
United Kingdom
Marcocci Claudio Prof., Università di Pisa, Dipartimento di Endocrinologia e di Metabolismo,
Via Paradisa 2, 56124 Pisa, Italy
Mourits Maarten Prof., Academic Medical Center, Orbital Center, Oculoplastic,
Reconstructive and Orbital Surgeon,
Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Orgiazzi Jacques Prof., Centre Hospitalier Lyon Sud, Médecine interne,
Endocrinologie et Métabolisme, 69495 Pierre Benite, France
Pearce Simon Prof., Institute of Human Genetics, International Centre for Life,
Central Parkway, NE1 3BZ, Newcastle upon Tyne, United Kingdom
Perros Petros Prof., Freeman Hospital, High Heaton, NE7 7DN,
Newcastle upon Tyne, United Kingdom
Pitz Susanne PD Dr. med., Johannes Gutenberg Universitätsklinikum, Augenklinik,
Orbitazentrum, Langenbeckstrasse 1, 55131 Mainz, Germany
Salvi Mario Prof., Università degli Studi di Milano, Unità di Endocrinologia,
Dipartimento di Scienze Mediche, Via Sforza 15, 20122 Milano, Italy
Sanders Jane Prof., FIRS Laboratories, RSR Ltd, Parc Ty Glas, Llanishen,
Cardiff CF14 5DU, United Kingdom
Schittkowski Michael PD Dr. med, Universitätsklinikum Göttingen, Augenklinik,
Georg-August-Universität, Robert-Koch-Strasse 40,
37075 Göttingen, Germany
Schott Matthias Prof., Klinik für Endokrinologie, Diabetologie und Rheumatologie,
Stv. Direktor der Klinik, Leiter Endokrinologie, Morenstrasse 5,
40225 Düsseldorf, Germany
Smith Terry J. Prof., University of Michigan Kellogg Eye Center, 1000 Wall Street,
Ann Arbor, MI, 48105, United States of America
21

22
INDEX OF FACULTY
Stahl Matthias Dr. med., Solothurner Spitäler AG, Kantonsspital Olten,
Stv. Chefarzt der Klink für Innere Medizin, Endokrinologie,
Baslerstrasse 150, 4600 Olten, Switzerland
Steinert Hans C. Prof. Dr. med., Universitätsspital Zürich, Klinik für Nuklearmedizin,
Rämistrasse 100, 8091 Zürich, Switzerland
Tyndall Alan Prof. Dr. med., Universitätsspital Basel, Chefarzt Rheumatologische
Universitätsklinik, Felix Platter Spital, Burgfelderstrasse 101,
4012 Basel, Switzerland
Villiger Peter M. Prof. Dr. med., Universität Bern, Inselspital, Universitätsklinik für
Rheumatologie, Klinische Immunologie, 3010 Bern 15, Switzerland
von Arx George F. Dr. med., ADMEDICO Augenzentrum, basedow.ch – Interdisziplinäres
Zentrum für Endokrine Orbitopathie, Facharzt FMH, Okuloplastische,
Rekonstruktive und Orbitachirurgie, Fährweg 10, 4600 Olten, Switzerland
Wall Jack Prof., University of Sydney, Nepean Hospital,
Department of Academic Medicine, Penrith, NSW, 2751, Australia
Wiersinga Wilmar Prof., University of Amsterdam, Academic Medical Center,
Department of Endocrinology, Meibergdreef 9,
1105 AZ Amsterdam, The Netherlands
Wong Susan F. Prof., University of Bristol, Dept. of Cellular & Molecular Medicine,
School of Medical Sciences, BS8 1TD Bristol, United Kingdom

ACKNOWLEDGEMENTS OF SPONSORS,
EXHIBITORS AND ADVERTISERS
The Chairman, Co-Chairmen and Scientific Committee members wish to express their gratitude
to all companies for their generous contribution and support to the 2 nd Swiss Symposium on
Thyroid Eye Disease and the Special Interest Symposium on Autoimmune Disease as
well as the Patient Plenary Session
AMO Switzerland GmbH, Abbott Medical Optics, 8808 Pfäffikon
Anklin AG, 4102 Binningen
Bausch & Lomb Swiss AG, Pharmazeutische Produkte, 6312 Steinhausen
Essilor (Suisse) SA, instruments d'optique, 1211 Genève 26
Eyemetrics Optic Service AG, 4053 Basel
Hirslanden Klinik Aarau, 5001 Aarau
Huco Vision SA, 2072 St-Blaise
Interpharma, Kontaktgruppe für Forschungsfragen, 4056 Basel
Laubscher & Co AG, 4434 Hölstein
medilas ag, 8954 Geroldswil
Merck Sharp & Dohme Inc., Ophtalmologie, 8152 Opfikon-Glattbrugg
Novartis Pharma AG, Scientific Affairs Basel Pharma Operations, 4056 Basel
Novartis Pharma Schweiz AG, 3001 Bern
sanofi-aventis (suisse) sa, produits et services pharmaceutiques, 1217 Meyrin
Siemens Schweiz AG, Healthcare, 8047 Zürich
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