The changing epidemiology of invasive aspergillosis

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Incidence <strong>of</strong> mucormycosis cases in a Belgian hospital from 2000 through 2009 • 31 patients: 21 proven, 10 probable • M/F: 16/15 • Mean age: 54 years (12-79 years) • 61% haematological patients • 45% co-infections with Aspergillus (halo-sign!) • Mortality rate = 65% (48%, directly related to infection) V. Saegeman et al., Emerg Infect Dis 2010, 16: 1456-1458.
Distribution <strong>of</strong> mucorales in France • « Retrozygo», 101 mucormycosis cases 2005-2007 Cunninghamella spp. 7% Other 8% Rhizomucor pusillus 7% Rhizopus oryzae 32% Rhizopus microsporus 17% Lichtheimia spp. 29% Lanternier F, CID 2012
Page 1 and 2: The changing epidemiology of invasi
Page 3 and 4: Question 1: What is correct? 00 1 I
Page 5 and 6: Incidence of fatal invasive mycoses
Page 7 and 8: Prospective data on culture 4 Danis
Page 9: Examples of at-risk patients and pa
Page 12 and 13: Adult HSCT recipients D. Kontoyiann
Page 14 and 15: Increased time to onset of IA in SO
Page 16 and 17: Anti-TNF→ granuloma suppression M
Page 18 and 19: Anti TNF & Histoplasma capsulatum 1
Page 20 and 21: Where in the hospital does invasive
Page 22 and 23: 1109 admissions Medical ICU 18 mont
Page 24 and 25: Clinical relevance of Aspergillus i
Page 31: Incidences of mucormycosis over 6 d
Page 35 and 36: Emergence of azole resistance in As

The changing epidemiology of invasive aspergillosis

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