The changing epidemiology of invasive aspergillosis

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1109 admissions Medical ICU 18 months (06/05-12/06) Modified EORTC criteria Solid cancer: n=23 Systemic disease: n=16 Solid organ transplants: n=6 COPD: n=15 Other n=6 Solid cancer; 2 n = 110 Hematological malignancy: n=36 Cirrhosis: n=23 Proven: n = 26 . Hematological malignancy Cirrhosis COPD Solid organ transplants Systemic disease Solid cancer Other Am J Resp Crit Care Med 2008, 177: 27-34. Systemic disease; 4 Solid organ ; 2 COPD; 2 Hematological malignancy; 11 Hematological malignancy 10% of Cirrhosis all admissions COPD at risk Solid organ Prospective study Systemic disease 2.3% proven Solid cancer aspergillosis Cirrhosis; 3
Ascioglu S et al. Defining opportunistic invasive fungal infection in immunocompromised patients with cancer and HSCT. Clin Infect Dis 2002; 34: 7-14 De Pauw B et al. Revised definitions of invasive fungal disease (EORTC/MSG consensus group) Clin Infect Dis 2008; 46: 1813-21
Page 1 and 2: The changing epidemiology of invasi
Page 3 and 4: Question 1: What is correct? 00 1 I
Page 5 and 6: Incidence of fatal invasive mycoses
Page 7 and 8: Prospective data on culture 4 Danis
Page 9: Examples of at-risk patients and pa
Page 12 and 13: Adult HSCT recipients D. Kontoyiann
Page 14 and 15: Increased time to onset of IA in SO
Page 16 and 17: Anti-TNF→ granuloma suppression M
Page 18 and 19: Anti TNF & Histoplasma capsulatum 1
Page 20 and 21: Where in the hospital does invasive
Page 24 and 25: Clinical relevance of Aspergillus i
Page 31 and 32: Incidences of mucormycosis over 6 d
Page 33 and 34: Distribution of mucorales in France
Page 35 and 36: Emergence of azole resistance in As

The changing epidemiology of invasive aspergillosis

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