The Indian Journal of Tuberculosis - LRS Institute of Tuberculosis ...

16 A.K. CHAKRABORTYCTAL ETAL
CF
efficiency
%
Current#
compliance
Table 6. DTP efficiency by varying proportional distribution of patients at
different compliance levels & case-finding efficiency
Sputum negative (%)* At
Compliance Hypothetically Varied**
1 2 3 4 5 6 7 8
(a)SR
33 16.40 19.09 19.94 20.79 21.64 22.07 24.19
40 19.88 23.14 24.17 25.20 26.24 26.75 29.32
50 24.86 28.93 30.22 31.51 32.80 33.44 36.65
60 29.83 34.72 36.26 37.81 39.35 40.12 43.98
70 34.80 40.50 42.30 44.11 45.91 46.81 51.31
80 39.77 46.29 48.34 50.41 52.47 53.50 58.64
90 44.74 52.07 54.39 56.71 59.03 60.19 65.97
100 49.71 57.86 60.43 63.01 65.59 66.88 73.30
(b) SCC
33 26.02 26.67 27.19 27.39 27.91 28.26 28.98
40 31.54 32.32 32.95 33.20 33.84 34.26 35.12
50 39.43 40.40 41.19 41.51 42.29 42.82 43.90
60 47.32 48.48 49.43 49.81 50.75 51.39 52.68
70 55.20 56.57 57.67 58.11 59.21 59.95 61.46
80 63.09 64.65 65.91 66.41 67.67 68.52 70.24
90 70.97 72.73 74.15 74.71 76.13 77.08 79.02
100 78.86 80.81 82.39 83.01 84.59 85.65 87.80
*DTP efficiency-negative status of cases at the end of treatment out of potential (2,000) computed on the basis of
respective sputum conversion rates for compliance structure given in columns 2 to 8 given in Appendix Table.;
** Structure of compliance:-please see Appendix Table
with SCC is calculated, except that improvement
with SCC over SR, when rates of compliance are
increased to 100% at level 4, increases only from
24% to 29% at CF efficiency of 33% (row 1 of
Table 6 Part b). The DTP efficiency at 100% CF
efficiency improves to nearly three times (78.9%)
the value attainable for CF efficiency at 33%, at
the current rates of compliance (column 2, last
rowofTable6b).
Compliance, regimen mixes, CF efficiency and
DTP efficiency
Another factor that could be studied through
the model is the effect of varying the mixes of
relative proportions of cases on SR and SCC. The
DTP efficiency at varying efficiencies of casefinding,
computed by varying hypothetically the
proportions of regimen mixes and compliance
structure by levels is given in Table 7. Only a few
compliance structures are shown, with one
currently seen in an operational study and
another with all the cases complying at 100% at
level 4, and two others with arbitrarily imputed
values, in order to illustrate the dynamics. One of
the latter two alternatives (structure 'b' in Table
7) is a close approximation of the situation in a
DTP with the best treatment compliance 9 . The
DTP efficiency increases by about 10%, if all the
cases are put on SCC instead of SR, at the current