The Indian Journal of Tuberculosis - LRS Institute of Tuberculosis ...

14 A.K. CHAKRABORTY ETAL
SCC would be 49.7% (situation I). The
corresponding efficiency for a DTP where all the
cases are put on SCC would work out to be 78.9%
(situation XI). For situations II to X, the expected
sputum conversion could be calculated to be
anywhere between 52.6% and 75.9%.
DTP efficiency under mixes
After bringing in the additional factor of
efficiency of case-finding, the estimated
proportions of cases converted out of the
potentially diagnosable cases (DTP efficiency)
are presented in Col. 8 of Table 3. The DTP
efficiency ranges from 16.4% to 26.0%.
Compliance & treatment efficiency
The above computations made respective to
the rates of compliance, in cases put on SR and
SCC at compliance levels of 1 to 4 are given in
Tables 1 and 2 respectively. Estimates of
treatment efficiency with hypothetically imposed
improvements in the rate of compliance are given
in Tables 4 & 5. Assuming that all the cases are
put on 100% SR or 100% SCC at level 4, (i.e.,
with 80% or more of drug consumption), the
treatment efficiency would be 73.3% & 87.8%
respectively (not on Table). However,
considering it to be an unrealistic situation, four
different assumptions on compliance structure
are worked out, with upto 70% of cases being
compliant at level 4 (Table 4). In this exercise, the
rates of compliance are gradually decreased at
the lower levels of compliance with proportionate
increase of the rates at the higher levels. Sputum
conversion under the varying proportions of
mixes with SR and SCC are then worked out,
Table 4. Treatment efficiency* by varying proportional distribution of cases on SR
& SCC at different compliance levels
Proportion of Cases complying at (%) (a)
On SR
Levels Current (:)
compliance
Compliance hypothetically varied
1
37 10 10 5 5
2 10 20 10 10 10
3 8 20 20 20 15
4 45 50 60 65 70
Overall 100 100 100 100 100
(49.71) (57.86) (60.43) (63.01) (64.30)
(Overall percentage of cases sputum negative in brackets)
(b) On SCC
1 20 10 5 5 5
2 4 10 10 5 5
3 20 20 20 25 20
4 56 60 65 65 70
Overall 100 100
(78.86) (80.81)
(Overall percentage of cases sputum negative in brackets)
100
(82.39)
100
(83.01)
100
(83.44)
(:) Observed from recent operational studies (Ref 10,11). See Tables 1 & 2; * Treatment efficiency-negative status
of cases at the end of treatment among cases diagnosed in DTP, computed on the basis of respective sputum
conversion rates for compliance given in columns 2 to 6 of parts a & b