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The Indian Journal of Tuberculosis - LRS Institute of Tuberculosis ...

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12 A.K. CHAKRABORTY ETAL<br />

<strong>The</strong> distribution <strong>of</strong> cases at the different levels<br />

<strong>of</strong> compliance is termed “compliance structure''.<br />

Sputum Conversion by levels <strong>of</strong> compliance : <strong>The</strong><br />

proportion <strong>of</strong> cases becoming sputum negative at<br />

the end <strong>of</strong> the prescribed period <strong>of</strong><br />

chemotherapy, by the various rates <strong>of</strong><br />

Mix <strong>of</strong> regimens : In those districts which have<br />

implemented SCC, not all the cases are put on<br />

SCC. <strong>The</strong> proportions put on SR and SCC would<br />

vary from DTP to DTP, ranging between two<br />

hypothetical extremes <strong>of</strong> 100% on SR with 0% on<br />

SCC at one end and 0% on SR with 100% on<br />

SCC at the other end. <strong>The</strong> situation <strong>of</strong> mix <strong>of</strong><br />

Table 1. Compliance and sputum conversion among 660 cases put on SR<br />

Compliance Structure @<br />

Sputum Negative<br />

Level Rate (%) Number** Rate (%) Number**<br />

1<br />

2<br />

37.0<br />

9.6<br />

244<br />

63<br />

21.7 -<br />

47.6<br />

53<br />

30<br />

3 7.9 52 47.6 25<br />

4 45.5 300 73.3 220<br />

Total 100.0 660 49.7* 328<br />

@ Compliance structure-see text; * Treatment efficiency with 100% SR = (328/660) x 100 = 49.7%; ** For value<br />

<strong>of</strong> cases, decimal points omitted<br />

Table 2. Compliance and sputum conversion among 660 cases put on SCC<br />

Compliance Structure @<br />

Sputum Negative<br />

Level Rate (%) Number** Rate (%) Number**<br />

1 20.3 134 56.3 75<br />

2 4.1 27 66.7 18<br />

3 19.6 129 79.2 102<br />

4 56.0 370 87.8 325<br />

Total 100.0 660 78.9* 520<br />

@ Compliance structure-see text; * Treatment efficiency with 100% SCC = (520/660) x 100 = 78.86%; ** For<br />

values <strong>of</strong> cases, decimal points omitted<br />

compliance, out <strong>of</strong> those actually put on<br />

treatment as observed in operational studies is<br />

computed in Tables 1 & 2 columns 4 & 5. <strong>The</strong><br />

computation is based on the observation that<br />

some proportions <strong>of</strong> cases become sputum<br />

negative in 1st, 2nd and 3rd levels <strong>of</strong> compliance<br />

and remain so even at the end <strong>of</strong> the stipulated<br />

period <strong>of</strong> treatment, inspite <strong>of</strong> not having<br />

consumed the prescribed number <strong>of</strong> doses <strong>of</strong><br />

drugs 10,11.<br />

regimens has been denoted in Roman numericals<br />

from I to XI in Table 3 & Figure.<br />

Treatment efficiency : (E,F,G in Fig.) It is the<br />

proportion <strong>of</strong> cases estimated to be sputum<br />

negative at the end <strong>of</strong> the treatment period out <strong>of</strong><br />

those put on treatment (i.e. the number<br />

converted out <strong>of</strong> 660 cases in district <strong>of</strong> average<br />

performance). Sputum conversions have been<br />

calculated taking into consideration the sum-total

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