The Indian Journal of Tuberculosis - LRS Institute of Tuberculosis ...
The Indian Journal of Tuberculosis - LRS Institute of Tuberculosis ...
The Indian Journal of Tuberculosis - LRS Institute of Tuberculosis ...
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12 A.K. CHAKRABORTY ETAL<br />
<strong>The</strong> distribution <strong>of</strong> cases at the different levels<br />
<strong>of</strong> compliance is termed “compliance structure''.<br />
Sputum Conversion by levels <strong>of</strong> compliance : <strong>The</strong><br />
proportion <strong>of</strong> cases becoming sputum negative at<br />
the end <strong>of</strong> the prescribed period <strong>of</strong><br />
chemotherapy, by the various rates <strong>of</strong><br />
Mix <strong>of</strong> regimens : In those districts which have<br />
implemented SCC, not all the cases are put on<br />
SCC. <strong>The</strong> proportions put on SR and SCC would<br />
vary from DTP to DTP, ranging between two<br />
hypothetical extremes <strong>of</strong> 100% on SR with 0% on<br />
SCC at one end and 0% on SR with 100% on<br />
SCC at the other end. <strong>The</strong> situation <strong>of</strong> mix <strong>of</strong><br />
Table 1. Compliance and sputum conversion among 660 cases put on SR<br />
Compliance Structure @<br />
Sputum Negative<br />
Level Rate (%) Number** Rate (%) Number**<br />
1<br />
2<br />
37.0<br />
9.6<br />
244<br />
63<br />
21.7 -<br />
47.6<br />
53<br />
30<br />
3 7.9 52 47.6 25<br />
4 45.5 300 73.3 220<br />
Total 100.0 660 49.7* 328<br />
@ Compliance structure-see text; * Treatment efficiency with 100% SR = (328/660) x 100 = 49.7%; ** For value<br />
<strong>of</strong> cases, decimal points omitted<br />
Table 2. Compliance and sputum conversion among 660 cases put on SCC<br />
Compliance Structure @<br />
Sputum Negative<br />
Level Rate (%) Number** Rate (%) Number**<br />
1 20.3 134 56.3 75<br />
2 4.1 27 66.7 18<br />
3 19.6 129 79.2 102<br />
4 56.0 370 87.8 325<br />
Total 100.0 660 78.9* 520<br />
@ Compliance structure-see text; * Treatment efficiency with 100% SCC = (520/660) x 100 = 78.86%; ** For<br />
values <strong>of</strong> cases, decimal points omitted<br />
compliance, out <strong>of</strong> those actually put on<br />
treatment as observed in operational studies is<br />
computed in Tables 1 & 2 columns 4 & 5. <strong>The</strong><br />
computation is based on the observation that<br />
some proportions <strong>of</strong> cases become sputum<br />
negative in 1st, 2nd and 3rd levels <strong>of</strong> compliance<br />
and remain so even at the end <strong>of</strong> the stipulated<br />
period <strong>of</strong> treatment, inspite <strong>of</strong> not having<br />
consumed the prescribed number <strong>of</strong> doses <strong>of</strong><br />
drugs 10,11.<br />
regimens has been denoted in Roman numericals<br />
from I to XI in Table 3 & Figure.<br />
Treatment efficiency : (E,F,G in Fig.) It is the<br />
proportion <strong>of</strong> cases estimated to be sputum<br />
negative at the end <strong>of</strong> the treatment period out <strong>of</strong><br />
those put on treatment (i.e. the number<br />
converted out <strong>of</strong> 660 cases in district <strong>of</strong> average<br />
performance). Sputum conversions have been<br />
calculated taking into consideration the sum-total