Lasers and photothermal therapy

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Photothermal <strong>therapy</strong> (PTT) Heat generated by laser can be used for: Biostimulation - accelerates healing of wounds Thermal <strong>therapy</strong> - heating (>45 o C) of maligant tissue Coagulation - sealing blood vessels, stopping bleeding Welding - joining of tissues, blood vessels Vaporisation - abblation of tissue (laser surgery) Shock-waves - removal of biliary, urinary, kidney stones
Photosensitizers - Low toxicity - Accumulation in biological targets - A large extinction coefficient - Photochemical stability PDT Generation of singlet oxygen Fluorescence diagnostics Photochemistry PTT Thermal relaxation No fluorescence No photochemical activity
Page 1 and 2: Lasers and Photothermal Therapy Pet
Page 3 and 4: Photodynamic therapy (PDT) Energy t
Page 5: Photothermal Therapy ϕωζ , ϕω
Page 9 and 10: Background Pulsed mode -10 -3 ÷ 10
Page 11 and 12: Light-tissue tissue interaction Abs
Page 13 and 14: Light-tissue tissue interaction Ref
Page 15 and 16: Light-tissue tissue interaction A.K
Page 17 and 18: Light-tissue tissue interaction W·
Page 19 and 20: Photothermal damage Thermal paramet
Page 21 and 22: Photothermal damage Thermal paramet
Page 23 and 24: Photothermal damage Single pulse of
Page 25 and 26: Photothermal damage Pulses with rep
Page 27 and 28: Photothermal damage Tissue damage f
Page 29 and 30: Photothermal damage Modifications i
Page 31 and 32: Photothermal damage R.R.Anderson an
Page 33 and 34: Excimer Ar Ruby Alexandrite Dye Dio
Page 35 and 36: Endogenous photosensitizers Melanin
Page 37 and 38: Hair Removal Selective Absorption i
Page 39 and 40: Endogenous photosensitizers Hemoglo
Page 41 and 42: Laser treatment of port wine stains
Page 43 and 44: Endogenous photosensitizers Collage
Page 45 and 46: Photothermal therapy in Ophthalmolo
Page 47 and 48: Exogenous photosensitizers Porphyri
Page 49 and 50: Exogenous photosensitizers Ni-octab
Page 51 and 52: Exogenous photosensitizers Cu(II)-h
Page 53 and 54: Conclusions Photothermal laser ther
Page 55: Thank you !

Lasers and photothermal therapy

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