Lasers and photothermal therapy
Lasers and photothermal therapy
Lasers and photothermal therapy
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Exogenous photosensitizers<br />
Pd-octabutoxy-naphthalocyanine<br />
PdNc(Obu) 8<br />
λ ε max = 827 nm<br />
BALB/c mice EMT6 tumour<br />
PdNc 0.6 ± 0.1 mg·kg -1 i.p. for 0-305 h<br />
Pharmacokinetics measured<br />
highest tumour / normal skin ratio<br />
highest tumour / muscle ratio<br />
~ 12 at 48-175 h<br />
20 ± 9 at 48-175 h<br />
M.Bucking et al. (2000) J.Photochem. Photobiol. B:Biol. 58, 87-93.