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Lasers and photothermal therapy

Lasers and photothermal therapy

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Exogenous photosensitizers<br />

Indocyanine green<br />

ICG<br />

λ ε max = 780 nm<br />

Wistar rats with implanted DMBA-4 tumours<br />

ICG 10 min. <strong>and</strong> 24 h intratumourally<br />

808 nm diode laser, 5-10 W, 3-5 min., 60 o C<br />

control (untreated)<br />

31.5 ± 3.7 days survival<br />

treated (ICG + laser) 29.9 ± 3.8 days survival<br />

lower rate of tumour growth<br />

W.R.Chen et al. (1996) Cancer Lett. 98, 169-173.<br />

M.Gurfinkel et al (2000) Photochem. Photobiol. 72, 94-102.

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