ABCD ABCD - Molecular Devices
ABCD ABCD - Molecular Devices
ABCD ABCD - Molecular Devices
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Hit confirmation<br />
<strong>ABCD</strong><br />
compound number<br />
3000<br />
2500<br />
2000<br />
1500<br />
1000<br />
500<br />
confirmed hits run 1<br />
primary hit rate: 3.1 %<br />
hits retested twice: ~23000<br />
confirmed hits: 21000<br />
confirmation rate: 90 %<br />
0<br />
< 0 100 200 300 400 500 600 700<br />
%CTL<br />
Ralf Heilker<br />
Dep. of Integrated Lead Discovery<br />
Counterscreen 1<br />
<strong>ABCD</strong><br />
I 0 hit<br />
α<br />
PLC<br />
Fluo[ ] Fluo[ ]<br />
Fluo[ ]<br />
Fluo[ ]<br />
Fluo[ ]<br />
Ca 2+ Ca 2+<br />
Ca 2+ Ca 2+<br />
Ca2+<br />
Ralf Heilker<br />
Dep. of Integrated Lead Discovery
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