ABCD ABCD - Molecular Devices
ABCD ABCD - Molecular Devices
ABCD ABCD - Molecular Devices
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Counterscreen 2<br />
<strong>ABCD</strong><br />
I 0 hit<br />
antagonist<br />
α<br />
PLC<br />
Fluo[ ] Fluo[ ]<br />
Fluo[ ]<br />
Fluo[ ]<br />
Fluo[ ]<br />
Ca 2+ Ca 2+<br />
Ca 2+ Ca 2+<br />
Ca2+<br />
Ralf Heilker<br />
Dep. of Integrated Lead Discovery<br />
Correlation of two counter screen runs in the<br />
presence of excess reference antagonist<br />
<strong>ABCD</strong><br />
compound number<br />
4000<br />
3500<br />
3000<br />
2500<br />
2000<br />
1500<br />
1000<br />
500<br />
~16000 specific hits, run 1<br />
0<br />
< 0 100 200 300 400 500 600<br />
% CTL<br />
Ralf Heilker<br />
Dep. of Integrated Lead Discovery