The Evolving Threat of ESBL, AmpC, and KPC -lactamases - SWACM
The Evolving Threat of ESBL, AmpC, and KPC -lactamases - SWACM
The Evolving Threat of ESBL, AmpC, and KPC -lactamases - SWACM
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Clinical Significance <strong>of</strong> <strong>AmpC</strong> for<br />
K. pneumoniae Bloodstream Isolates<br />
Clinical<br />
DHA-1<br />
(inducible)<br />
CMY-1 like<br />
Extended-spectrum<br />
Cephalosporin as<br />
definitive therapy<br />
Failed CTX/CAZ;<br />
improved on<br />
carbapenem<br />
4/4 died 1/3 died<br />
6 5<br />
30 day mortality 46% 14.3%<br />
DHA-1 (13 pts), CMY (14 pts) Pai et al. AAC 2004 48:3720-28