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The Evolving Threat of ESBL, AmpC, and KPC -lactamases - SWACM

The Evolving Threat of ESBL, AmpC, and KPC -lactamases - SWACM

The Evolving Threat of ESBL, AmpC, and KPC -lactamases - SWACM

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CLSI 2010 (M100-S20)<br />

• If laboratories have not yet implemented the new<br />

interpretive criteria, test for <strong>ESBL</strong>s. For positive<br />

isolates:<br />

Report resistance to all penicillins, cephalosporins<br />

<strong>and</strong> aztreonam if E. coli, Klebsiella spp, or Proteus<br />

mirabilis<br />

• If laboratories have implemented the new criteria, do<br />

not test for <strong>ESBL</strong>s for therapy (Only test if required<br />

for infection control)<br />

Report susceptibility as interpreted

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