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We provide cost-effective solutions that work for you.<br />

Why take a chance on anyone else?


Whether your medical device assembly requires an<br />

adhesive that is biocompatible and sterilizable – or one that<br />

meets a host of other performance characteristics – Henkel<br />

has the right adhesive for your application.<br />

Our adhesives have been specified by medical device<br />

manufacturers all over the world for over two decades.<br />

Our experience, products, and engineering services are second<br />

to none, with the world’s most diversified and comprehensive<br />

line of adhesives, dispensing equipment, and curing systems<br />

available anywhere. We offer over forty products for medical<br />

device assemblies requiring biocompatibility testing and<br />

hundreds of other products for applications not requiring<br />

such evaluation.<br />

Adhesives can provide design advantages, improve overall<br />

product performance, speed assembly time, and increase<br />

production efficiency and quality. <strong>Loctite</strong> ® adhesives combine<br />

all of these advantages, and more. When the total cost of<br />

a finished medical device is considered, adhesives are the<br />

most economical assembly choice. <strong>Loctite</strong> ® adhesives offer<br />

many benefits, including:<br />

▲ Structural Bonds<br />

▲ Ability to Bond Dissimilar and Difficult Substrates<br />

▲ Increased Throughput<br />

▲ Rapid Fixture and Overall Cure Times<br />

▲ Excellent Gap Filling Capability<br />

▲ Even Stress Distribution<br />

▲ Comprehensive Biocompatibility Testing


Our medical device adhesives cover a variety of chemistries, providing you with<br />

a wide range of choices and assembly solutions. We know one product won’t fit<br />

every design, and that’s why we continue to create and add new products, new<br />

chemistries, and even new technologies.<br />

All of our products are available in viscosities ranging from water-thin liquids to<br />

thixotropic gels and are compatible with common sterilization methods such as<br />

ethylene oxide, gamma radiation, electron beam, liquid sterilization, autoclave,<br />

and peroxide plasma.<br />

LIGHT CURING ADHESIVES<br />

Upon exposure to the appropriate light source, these onepart<br />

adhesives cure completely in seconds to form<br />

thermoset or thermoplastic polymers (depending on the<br />

chemistry) with excellent adhesion to a wide variety of<br />

substrates. Cure times from two to thirty seconds are typical.<br />

Light Curing Acrylics – These products offer the most<br />

extensive variety of properties of all light cure chemistries.<br />

Upon exposure to suitable light, acrylics produce tough,<br />

durable thermoset polymers. Cured properties range from<br />

hard and rigid to soft and flexible. Newer products cure<br />

under either UV or visible light sources and respond to low, medium, or high intensity light.<br />

Easily automated, fluorescent versions allow in-line detection of the adhesive.<br />

Light curing acrylics are used to assemble syringes, injectors, infusion sets, pressure<br />

transducers, drug delivery devices, IV sets, oxygenators, cardiotomy reservoirs, blood heat<br />

exchangers, hearing aids, anesthesia masks, and blood filters.<br />

Light Curing Cyanoacrylates – <strong>Loctite</strong> ® FlashCure ® light curing cyanoacrylates are well<br />

suited for applications where a secondary moisture cure is required, allowing the adhesive<br />

to cure completely in shadowed areas where light cannot reach. Exposure to low intensity<br />

UV or visible light provides tack-free surfaces in less than five<br />

seconds. These adhesives eliminate the need for solvent-borne<br />

accelerators and minimize stress cracking and blooming<br />

(a whiteness around the bondline), due to their “instant” fixturing.<br />

Light curing cyanoacrylates are ideal for the assembly of<br />

catheters, syringes, pressure transducers, orthopedic devices,<br />

infusion pumps, oxygen concentrators, blood gas analyzers,<br />

filters, as well as a number of other devices.<br />

Light Curing Silicones – When exposed to high intensity UV<br />

light, <strong>Loctite</strong> ® Nuva-Sil ® silicones cure into soft, flexible thermoset<br />

elastomers. Light curing silicones are excellent for sealing, gasketing and leakproofing, and<br />

are well suited for bonding silicone rubber.<br />

Light curing silicone applications include tracheal and endotracheal tubes, foley catheters,<br />

colostomy devices, and chest drainage tubes.


CYANOACRYLATE ADHESIVES<br />

These one-part adhesives cure in seconds at room temperature, forming slightly flexible to<br />

rigid thermoplastics. They are particularly suited for joining dissimilar substrates in almost any<br />

combination including polyolefins, thermoplastics, rubber, and metals. <strong>Loctite</strong> ® Prism ®<br />

cyanoacrylates are high performance instant adhesives designed for the most challenging<br />

applications. The Prism ® family includes flexible, toughened, low odor/low bloom, surface<br />

insensitive, and thermally resistant formulations.<br />

Cyanoacrylates are widely used to bond components in the assembly of blood pressure<br />

transducers, endoscopes, IV sets, infusion pumps, catheters, orthopedic devices, hearing<br />

aids, cast boots, and diagnostic imaging equipment.<br />

CYANOACRYLATE ACCELERATORS AND PRIMERS<br />

Accelerators speed the cure of cyanoacrylates and are used to reduce fixture and cure times,<br />

or to cure fillets on bondlines and/or exposed adhesive. They can be applied to a substrate<br />

prior to the application of cyanoacrylate adhesive or they can be sprayed over a drop or<br />

fillet to initiate a rapid cure. Primers enable the cyanoacrylate to form strong bonds with<br />

polyolefins and other difficult plastics such as acetal resins. Depending on the plastic, bond<br />

strengths up to 20 times the unprimed bond strength may be achieved.<br />

EPOXY ADHESIVES<br />

<strong>Loctite</strong> ® Hysol ® epoxies provide high peel and shear strength on a wide variety of plastics<br />

and metals. When cured, these crosslinking thermoset plastics offer superior thermal and<br />

chemical resistance, as well as high cohesive strength and minimal shrinkage. Hysol ®<br />

two-part systems are packaged in side-by-side cartridges, allowing them to be dispensed<br />

as easily as any one part system.<br />

Our new single component, heat cure formulas are excellent for bonding metals to a wide<br />

variety of plastics, providing superior pull strength when joining cannulae to hubs or syringes.<br />

Epoxies are commonly used on endoscopes, catheters, artherectomy devices, blood heat<br />

exchangers, syringes, and dental, surgical and orthopedic instruments.<br />

POLYURETHANE ADHESIVES<br />

<strong>Loctite</strong> ® Hysol ® urethanes are ideal for bonding metals, plastics, glass, and other<br />

substrates. Designed for potting and encapsulating applications, these two-part, room<br />

temperature curing products provide excellent peel and shear strength. They are ideal for<br />

opaque substrates that require high flexibility.<br />

Urethanes are commonly used in potting applications on filters, kidney dialyzers,<br />

blood heat exchangers, and catheters.


CATHETER SAFETY INCREASED<br />

A thermal dilution catheter manufacturer<br />

requested assistance for bonding a latex<br />

balloon to a rigid, multi-lumen PVC tube. The<br />

catheter is inserted into a major vein near the<br />

heart to take blood samples, administer fluids,<br />

and monitor blood pressure and body<br />

temperature. The transducer must endure<br />

temperatures ranging from freezing to 110°F,<br />

while the balloon must withstand pressures up<br />

to 110 lbs. After bonding, the balloon is inflated<br />

fifty times to check bond durability.<br />

TOXIC SOLVENTS<br />

ELIMINATED<br />

<strong>Loctite</strong> ® 4014 cyanoacrylate<br />

secures a latex balloon to<br />

rigid PVC tubing.<br />

<strong>Loctite</strong> ® 4014 cyanoacrylate was selected on the balloon<br />

bond, for its low viscosity, thermal resistance and controlled<br />

setting time. This allowed time to assemble and place the<br />

balloon precisely. The customer reports that the adhesive<br />

works so well that “the balloon ruptures before the adhesive<br />

fails.”<br />

<strong>Loctite</strong> ® 4011 replaced solvent<br />

bonding in this PVC tube to<br />

copolymer fistula assembly.<br />

VETERINARY DEVICE SECURED<br />

Animal drugs for livestock management<br />

and the introduction of new vaccines and<br />

drug treatments have led to new delivery<br />

techniques in veterinary device technology.<br />

Since the FDA does not require the same<br />

standards for animal devices as those<br />

required for medical devices intended for<br />

humans, manufacturers may use nonmedical<br />

products. Their responsibility is to<br />

assure that the animal medical device is<br />

<strong>Loctite</strong> ® 406, an industrial cyanoacrylate, joins<br />

safe, effective, and properly labeled.<br />

polypropylene to polypropylene, on this veterinary<br />

syringe, increasing product quality and safety.<br />

Most syringes used for animal injections<br />

are made of solvent resistant polypropylene (PP). Because of the difficulty in joining PP, snap<br />

fittings are frequently used to connect tubes and barrels. However, the soft and pliable nature<br />

of PP often results in poor performance or joint failures. Because livestock is very expensive,<br />

if a syringe breaks during an injection it could mean the loss of an expensive drug, as well as<br />

internal injury to the animal, should the broken section be swallowed by a valuable<br />

racehorse, for example.<br />

To permanently connect the components, <strong>Loctite</strong> ® 406, a low viscosity adhesive, was<br />

selected for its ability to bond difficult substrates. <strong>Loctite</strong> ® 770 polyolefin primer was applied<br />

to the PP, prior to applying the cyanoacrylate, to obtain maximum bond strength. The bonded<br />

parts met every drug resistance and strength test required by the manufacturer.<br />

Note: For medical devices intended for humans, <strong>Loctite</strong> ® 4061 adhesive and 7701 primer<br />

are recommended, as they comply with extensive biocompatibility testing.<br />

A manufacturer of a device used in dialysis<br />

machines to withdraw and return blood had<br />

a production line shut down. The problem:<br />

one vendor had supplied out-of-tolerance<br />

parts, and the solvent used for bonding<br />

could not fill the excessive gap. Their PVC<br />

tubing supplier also made a substitution,<br />

creating additional assembly problems.<br />

The assembly process used solvent welding,<br />

a mixture of 90% methylene chloride and<br />

10% cyclohexanone, to join a flexible PVC<br />

tube to a copolymer elastomer (TPE). The<br />

parts were joined by slip fit, with a gap of<br />

.002", using a dip and assemble technique.<br />

The assembled product had to meet a 20-25<br />

psi burst test and a 15 lb. pull test.<br />

<strong>Loctite</strong> ® 4011, a surface insensitive<br />

cyanoacrylate, was specified. It filled the<br />

gap and had enough strength to pass the<br />

burst and pull tests with ease. Since the<br />

manufacturer already used <strong>Loctite</strong> ® 4011<br />

in another area of the plant, making the<br />

switch was easy. Production goals were<br />

met, inventory was used, product quality<br />

was assured, and a potentially troublesome<br />

toxic solvent was eliminated.


SOLVENTS AND STRESS<br />

CRACKING ELIMINATED<br />

This soft, flexible catheter uses a “peel<br />

away,” splitable needle introducer, a unique<br />

catheter insertion system for fragile veins.<br />

After insertion, the needle’s wing assembly<br />

is split apart and discarded, eliminating the<br />

need to repeatedly restick the patient.<br />

BOND STRENGTH INCREASES<br />

5X ON SAFETY SYRINGES<br />

<strong>Loctite</strong> ® 3211 improves product<br />

quality, reduces rejects and<br />

eliminates toxic solvent fumes during<br />

assembly of this micro-catheter.<br />

STRONG, FLEXIBLE<br />

BONDS ACHIEVED<br />

<strong>Loctite</strong> ® Prism ® 410 is used to<br />

lock the stainless steel threaded<br />

fastener into position during<br />

the customized fitting of this<br />

prosthesis.<br />

FOUR-SECOND CURE<br />

DOUBLES PRODUCTION<br />

The manufacturer was dissatisfied with the<br />

process used to bond the stainless steel<br />

needle halves to lightly-tinted polycarbonate<br />

wings. A “solvent cocktail,” made by<br />

combining a plastic, such as PVC pellets,<br />

and adding solvent, to make a “glue,” was<br />

being used. Formulation inconsistency, stress cracking, and<br />

toxic solvent fumes were growing concerns.<br />

The solution, <strong>Loctite</strong> ® 3211 was specified along with a<br />

<strong>Loctite</strong> ® light cure chamber. The combination proved superior<br />

in every way – eliminating stress cracking while reducing<br />

rejects due to the solvent cocktail’s inconsistencies.<br />

This lower limb prosthetic device manufacturer builds<br />

prostheses made of carbon fiber, a material known for its<br />

superior strength, flexibility, and imperviousness to the<br />

elements as well as corrosion and stress. They wanted to<br />

provide amputees with proportional response, an active heel<br />

with natural ankle motion and a 95% energy return that<br />

actually powers the wearer through each step.<br />

<strong>Loctite</strong> ® 410 Prism ® , a black, rubber toughened industrial<br />

cyanoacrylate, provides the flexibility required to maintain<br />

appropriate fastener torque on the stainless steel fastener<br />

used in customizing the fit of these prostheses. The product is<br />

easily visible and removable, and is applied without activators<br />

or primers. <strong>Loctite</strong> ® 277 industrial threadlocker is used for the<br />

larger 1" pre-assembled fasteners to prevent loosening while in<br />

use. This customer uses <strong>Loctite</strong> ® products throughout their<br />

manufacturing facility, to provide strong, flexible bonds on their<br />

line of products.<br />

<strong>Loctite</strong> ® 3051 bonds K-Resin ® to stainless<br />

steel cannulae in dental syringes,<br />

increasing product quality. Ready for<br />

injection (left), and K-Resin guard covering<br />

needle after injection (right).<br />

This syringe, with pre-attached needles, is designed to<br />

prevent accidental needlesticks in the dental industry.<br />

An anesthesia cartridge is loaded into the K-Resin ®<br />

body assembly, which penetrates the back of the<br />

needle, allowing the anesthesia to flow into the<br />

syringe. After the injection is made, a second guard<br />

slides down over the needle, fully enclosing it.<br />

Traditional dental syringes involve multiple chances to<br />

get stuck with “screw-on” needles.<br />

Henkel was called upon in the design stage to analyze<br />

the application, which involved bonding a stainless<br />

steel cannula to a K-Resin ® syringe body. Heat cure<br />

epoxies were evaluated, but the heat caused the<br />

viscosity of the epoxy to decrease, resulting in<br />

occluded needles and misaligned parts. The customer<br />

required consistency, automation, and a minimum pull<br />

strength of 4.4 lbs.<br />

<strong>Loctite</strong> ® 3051 was evaluated and proved superior on<br />

the substrates. It was easily automated and eliminated<br />

heat cures and migrating epoxy issues. Cure time was<br />

4-5 seconds under a <strong>Loctite</strong> ® high intensity light cure<br />

conveyor. Production and product quality increased<br />

significantly, allowing the customer to achieve 4-5<br />

times greater pull strength, delivering 20 lbs. versus<br />

the 4.4 lbs. required.<br />

A manufacturer wanted a better way to assemble anesthesia masks in order to double production. The<br />

substrates they were bonding were rigid cones to flexible, highly plasticized PVC face cushions. The masks<br />

were assembled with a cyanoacrylate that required 9 seconds to fixture and several hours to fully cure.<br />

Some brittleness and blooming during and after cure was experienced, with rework and rejections running<br />

high. A peel test demonstrating substrate failure was required, and no oxygen leakage could be exhibited<br />

from the mask after bonding.<br />

Rigid to highly plasticized PVC is<br />

bonded easily with <strong>Loctite</strong> ® 3341<br />

on anesthesia masks.<br />

<strong>Loctite</strong> ® 3341 proved to be the superior alternative, passing all tests and requiring only 4 seconds for<br />

complete cure under a <strong>Loctite</strong> ® medium-intensity light cure conveyor. This enabled the customer to not only<br />

double production by adding another shift, it also presented a significant cost savings over their prior<br />

cyanoacrylate usage.


ENVIRONMENTAL CONCERNS<br />

ELIMINATED FOR<br />

COLLECTION RESERVOIR<br />

LIGHT CURE TECHNOLOGY<br />

IMPROVES APPEARANCE AND<br />

SPEEDS PRODUCTION<br />

Hearing aid manufacturers have long relied on adhesives for the assembly<br />

of various hearing aid components including face plates and receiver<br />

components. Recent advances in light curing technology have allowed for<br />

increased throughput and reliability.<br />

<strong>Loctite</strong> ® Flashcure ® cyanoacrylates are single component light curing<br />

adhesives. With exposure to low intensity light, the Flashcure ® products<br />

cure in seconds offering strong faceplate and componentry bonds. The<br />

need for solvent-based cyanoacrylate accelerators is eliminated and the<br />

potential for blooming (a whiteness around the bond line) is reduced.<br />

<strong>Loctite</strong> ® 3211 eliminates solvents and<br />

provides structural strength for<br />

collection reservoir.<br />

A leading manufacturer of blood collection and<br />

processing systems used solvents such as<br />

methylene chloride for bonding various device<br />

components and subassemblies. OSHA and the<br />

EPA were encouraging industries to move away<br />

from using solvents, and this device manufacturer<br />

particularly wanted to eliminate their use of<br />

methylene chloride. Since the devices were made<br />

of glass-like plastics, their engineers required<br />

clear bonds with no stress cracking or crazing.<br />

The collection reservoir, a disposable device<br />

used to clean and return blood to patients during<br />

various surgical procedures, consists of a clear,<br />

polycarbonate lid assembly joined to a<br />

polycarbonate bucket. Environmental concerns<br />

and issues associated with solvent bonding were<br />

eliminated with a new tongue and groove design<br />

and with <strong>Loctite</strong> ® 3211 – a safer, faster and<br />

more consistent bonding choice. <strong>Loctite</strong> ® 3211<br />

light curing adhesive provided the aesthetic<br />

bondline the manufacturer wanted. It also<br />

provided the structural strength that the<br />

collection reservoir manufacturer needed to<br />

maintain a competitive edge in the marketplace.<br />

<strong>Loctite</strong> ® Nuva-Sil ® silicones are single component, light/moisture curing<br />

adhesives/sealants. The rapid cure with exposure to high intensity light<br />

makes the dual curing silicones the products of choice for the bonding of<br />

the receiver tube to the receiver, and the bonding of the receiver tube to<br />

the shell for hearing aid shell fabrication.<br />

<strong>Loctite</strong> ® customdesigned<br />

needle<br />

specimens are used<br />

to verify adhesive<br />

application and<br />

performance.<br />

ON-PART DETECTION ENSURES<br />

QUALITY AND RELIABILITY<br />

<strong>Loctite</strong> ® light cure products<br />

allow for the rapid and reliable<br />

assembly of hearing aids.<br />

Adhesives are universally used for bonding cannulae to hubs in needle assemblies. It is<br />

critical that this joint is well bonded and sealed to prevent fluids such as blood or medicine<br />

from leaking. It is also essential that the position of the cannula remains fixed.<br />

All <strong>Loctite</strong> ® needle bonding adhesives are fluorescent to facilitate final inspection of the<br />

adhesive joint, ensuring that the adhesive is not only present but also that the adhesive<br />

has flowed into the bond joint correctly. The <strong>Loctite</strong> ® Fluorescent Detector is used to<br />

perform a present or not present inspection. If more precision is desired, the<br />

fluorescence can be monitored using a vision system, albeit at much higher expense.<br />

Henkel offers the most extensive line of needle bonding adhesives. These<br />

UV/visible acrylic and/or one-part epoxy products are specifically designed for<br />

the assembly of stainless steel cannulae to a variety of hub materials including<br />

polycarbonate, acrylic, ABS, and polypropylene. The wide range of adhesives<br />

includes viscosity, environmental, substrate and performance variations to ensure<br />

that there is a product to meet any needle bonding application requirement.<br />

INNOVATIVE DEVICE PACKAGING SOLVES SAFETY HAZARD<br />

For years, a swab device in combination with a reagent filled glass ampule has been used for various diagnostic<br />

tests. Following sample collection, the glass ampule was broken releasing the test reagent for use in the analysis.<br />

Problems with the procedure included the possibility that glass shards could cut the technician, clog the dropper<br />

tube or get into the reagent. The development of an innovative package allowed for increased safety and a<br />

patented product offering the manufacturer a competitive advantage in a very large market.<br />

The new product was designated the SnapSwab and consisted of a Dacron ® swab tip on a polystyrene shaft<br />

encased in a polyethylene tube. In use, a quick snap of the swab shaft releases the reagent and the swab is ready<br />

for use. It was necessary to reliably attach the swab to the inside of the tube and ensure the entire assembly be<br />

leak proof.<br />

<strong>Loctite</strong> ® 3311 offers adhesion to<br />

various swab substrates, resulting<br />

in a safer and more reliable device.<br />

<strong>Loctite</strong> ® 3311, a single component light cure acrylic adhesive, was the material of choice for the new swab<br />

device. Rapid, semi-automated processing, and high adhesion to the various swab substrates resulted in a device<br />

that was safe, convenient, dependable, and inexpensive.


DISPENSING<br />

<strong>Loctite</strong> ® 3211 Light Cure Acrylic is dispensed<br />

onto a polycarbonate fluid reservoir.<br />

Henkel offers a complete line of dispensing, curing and process monitoring<br />

equipment designed specifically for use with our medical device adhesives.<br />

Our dispensing equipment options range from manual and semi-automatic to<br />

fully automatic systems, along with a complete line of accessories, such as<br />

needles, nozzles, and syringes. Our dispensing technology enables customers<br />

to apply drops or beads of adhesives, making precise application of <strong>Loctite</strong> ®<br />

products economical, fast, and clean.<br />

We offer custom engineered systems for<br />

turnkey integration in high speed assembly<br />

processes. If your future production plans<br />

include significant growth, Henkel can even<br />

show you the advantages of installing a<br />

flexible system that can grow with your<br />

changing needs.<br />

CURING<br />

Anesthesia masks are cured following assembly<br />

with a flexible <strong>Loctite</strong> ® light cure acrylic adhesive.<br />

A variety of light curing systems, ranging<br />

from portable curing wands to modular flood<br />

chambers, and benchtop conveyors, are<br />

available. All of our light cure equipment is<br />

engineered to match the spectral output of<br />

our range of light curing adhesives. As a<br />

manufacturer of both the adhesive and curing<br />

equipment, we understand the chemistry and the process needed to cure our<br />

products properly, so you can be assured of obtaining the maximum bond<br />

strength and cure speeds. Matching the adhesive to the correct curing system<br />

will optimize your assembly process and help you attain the fastest, most<br />

consistent cures. We offer a full line of accessories, including radiometers,<br />

replacement bulbs, and UV safety glasses.<br />

Henkel’s state-of-the-art detection systems allow for real time process<br />

monitoring of dispense cycles. Whether you are trying to determine the<br />

presence of adhesive via fluorescence detection, or the amount of adhesive<br />

dispensed from an individual dispense nozzle, Henkel has the system that will<br />

get the job done with high degrees of precision and reliability.<br />

Henkel also provides engineering resources to assist customers in developing<br />

manufacturing and assembly processes which effectively integrate on-line<br />

dispensing and curing equipment. Rental and repair services are also offered,<br />

affording customers the opportunity to fully evaluate a process and equipment<br />

prior to making a capital investment.<br />

PROCESS MONITORING<br />

The <strong>Loctite</strong> ® Fluorescence Detector is used<br />

to verify adhesive application on<br />

needle assemblies.<br />

For more information on our complete line of dispensing, curing and<br />

process monitoring equipment, visit us at equipment.loctite.com


Our goal is to become your adhesive consultant. Whether you need a quick product<br />

recommendation, or a full-blown turnkey process, Henkel Engineering Services can provide the<br />

right solution. Our skilled engineers have years of combined experience developing hundreds of<br />

solutions for medical device manufacturers. Consult with Henkel and gain access to:<br />

▲ The best product and process solution for your specific application<br />

▲ Products tested and in compliance with our ISO-10993 Biocompatibility Test<br />

Program – the most comprehensive in the industry<br />

▲ Highly trained and skilled specialists with the know-how to consult,<br />

troubleshoot, and solve problems<br />

▲ On-site product and application training and support<br />

▲ State-of-the-art parts testing and evaluation facilities to simulate a<br />

wide range of environments<br />

Whether we are reducing your assembly costs, providing design and<br />

application assistance, or increasing the reliability of your process, Henkel<br />

is dedicated to earning your trust. Count on Henkel to be your sole<br />

source for all of your medical device applications.<br />

Henkel offers training programs that provide additional support to device<br />

manufacturers around the globe. Training continues after the seminar: you are linked to<br />

a network of informational sources including adhesive design guides, research data, and technical reports.<br />

Advanced Medical Device Adhesive Workshops: These unique, fully integrated, four to seven hour<br />

programs are taught by Henkel engineering and technical representatives who have years of experience<br />

providing solutions to medical device manufacturers on design and assembly challenges. Presenters will<br />

review a range of issues specifically related to the medical device industry. Attendees will benefit from<br />

hands-on demonstrations of adhesives and equipment.<br />

For dates and locations of up-coming Advanced Medical Device Adhesive Workshops, log onto our<br />

website at www.loctite.com/medical.<br />

On-Site Technology Seminars: A training program customized to your needs. Select from a menu of seven of<br />

the most requested medical device adhesive topics or request a customized seminar to meet your specific<br />

requirements. The course will be presented on-site and will include instruction, hands-on demos, samples,<br />

and technical guides.<br />

For more information on the On-Site Seminar program, contact Henkel at 1-800-LOCTITE.<br />

We support our customers with a service program that is unmatched by<br />

others in the industry. It’s what sets Henkel apart.


<strong>Loctite</strong> ® Brand Appearance Fluorescent Cure Method Viscosity, cP Temperature Shore Hardness Modulus (psi) Cure Depth** Substrates Product Features Needle Catheters Reservoir Respiratory Sutures Tube Sets Endoscopes Hearing Item Package Item Package Product<br />

Product Range (°F) (inches) Bonding Assemblies Aids Number Size Number Size<br />

LIGHT CURE ACRYLICS<br />

3201 transparent/hazy N UV, V 4,000 -65 to 300 59 (D) 43,000 0.05 PC, TP, ME, G Highly flexible PC adhesive, minimal stress cracking X 19727 25 ml 19728 1 liter 3201 <br />

3211 transparent/hazy N UV, V 10,000 (thixotropic) -65 to 300 51 (D) 30,000 0.06 PC, TP, ME, G Non-migrating, very flexible PC adhesive, minimal stress cracking X 19730 25 ml 19731 † 1 liter 3211 <br />

3301 transparent N UV, V 150 -65 to 300 69 (D) 107,000 0.10 PVC, PC, TP, ME, G Slightly flexible, excellent on PVC X X 19733 25 ml 19734 1 liter 3301 <br />

3311 transparent N UV, V 300 -65 to 300 64 (D) 97,000 0.09 PVC, PC, TP, ME, G Flexible, excellent on PVC and most thermoplastics X 19736 25 ml 19737 1 liter 3311 <br />

3321 transparent N UV, V 5,000 -65 to 300 53 (D) 37,000 0.08 PVC, PC, TP, ME, G Flexible, ideal for thermoplastics X 19739 25 ml 19740 1 liter 3321 <br />

3341 transparent/light yellow Y UV, V 450 -65 to 300 27 (D) 36,000 0.12 PVC, TP Excellent on highly plasticized PVC and other difficult-to-bond substrates X X X X X 23792 25 ml 23440 1 liter 3341 <br />

3345 clear/light straw N UV 1,500 -65 to 260 70 (D) 180,000 0.08 G, ME Excellent for glass to metal X 33417 25 ml 30688 † 1 liter 3345 <br />

3381 translucent/colorless N UV 5,000 -65 to 300 72 (A) 2,670 0.10 TP, TSP Extremely flexible, thermal cycling resistant X 25785 25 ml 24690 † 1 liter 3381 <br />

3911 transparent/hazy Y UV, V 100 -65 to 300 65 (D) 20,250 0.07 G, ME, TP Low viscosity, low moisture absorption X X 36536 25 ml 36537 † 1 liter 3911 <br />

3912 transparent/hazy Y UV, V 6,300 -65 to 300 60 (D) 20,750 0.07 G, ME, TP Medium viscosity, low moisture absorption X X 36539 25 ml 36540 1 liter 3912 <br />

3913 transparent Y UV 8,500 -65 to 300 64 (D) 31,500 0.09 G, ME, TP Highly fluorescent X X 36791 25 ml 36804 1 liter 3913 <br />

3921 transparent/hazy Y UV, V 150 -65 to 300 67 (D) 122,750 0.08 PVC, PC, TP, ME G Highly fluorescent, superior sterilization resistance X X X 36484 25 ml 36485 1 liter 3921 <br />

3922 transparent/hazy Y UV, V 300 -65 to 300 66 (D) 91,500 0.12 PVC, PC, TP, ME, G Superior sterilization resistance, excellent adhesion to PC X X 32083 25 ml 32047 † 1 liter 3922 <br />

3924 transparent/hazy Y UV, V 1,100 -65 to 300 60 (D) 41,100 0.10 PVC, PC, TP, ME, G Superior sterilization resistance, excellent adhesion to various TSP X X X X 36488 25 ml 36489 1 liter 3924 <br />

3926 transparent/hazy Y UV, V 5,500 -65 to 300 57 (D) 20,700 0.10 PVC, PC, TP, ME, G Highly fluorescent, superior sterilization resistance X X 36492 25 ml 36493 1 liter 3926 <br />

3933 transparent/hazy Y UV, V 3,250 -65 to 300 57 (D) 47,000 0.04 PC, TP, ME, G Excellent on PC and other TP X X 32084 25 ml 32040 † 1 liter 3933 <br />

3936 transparent/hazy Y UV, V 10,000 -65 to 300 55 (D) 24,500 0.08 PC, TP, ME, G Highly flexible, excellent on PC and other TP X 32304 25 ml 32037 † 1 liter 3936 <br />

3941 transparent/hazy Y UV, V 480 -65 to 300 74 (D) 184,000 0.06 G, ME, TP, TSP Highly fluorescent, rapid tack-free curing X X 36437 25 ml 36476 1 liter 3941 <br />

3942 transparent/hazy Y UV, V 1,100 -65 to 300 76 (D) 142,900 0.11 G, ME, TP, TSP High performance, rapid tack-free curing X X 36483 25 ml 36481 1 liter 3942 <br />

3943 transparent/hazy Y UV, V 6,000 -65 to 300 69 (D) 64,000 0.12 G, ME, TP, TSP Tough, superior tack-free curing X X 36480 25 ml 36478 1 liter 3943 <br />

3944 fluorescent/pale yellow Y UV, V 5,000 -65 to 300 50 (D)* 57,000 0.15 PVC, PC, TP, ME, G Superior surface curing, very flexible X 38210 25 ml 38212 † 1 liter 3944 <br />

3971 transparent Y UV, V 300 -65 to 300 71 (D) 95,000 0.16 PVC, TP, ME Superior tack-free curing, low viscosity X X X X 36792 25 ml 36805 1 liter 3971 <br />

3972 transparent/hazy Y UV, V 4,500 -65 to 300 68 (D) 66,750 0.25 PVC, TP, ME Superior tack-free curing, moderate viscosity X X X X X 36294 25 ml 36295 1 liter 3972 <br />

LIGHT CURE CYANOACRYLATES<br />

4306 light amber/light green Y UV, V, M 20 -65 to 180 82 (D) 250,700 0.15 TP, PC, E, ME Rapid tack-free surface and shadow curing, low viscosity X X X X X X 37439 1 oz. 37442 † 1 lb. 4306 <br />

4307 light amber/light green Y UV, V, M 900 -65 to 180 82 (D) 262,900 0.17 TP, PC, E, ME Rapid tack-free surface and shadow curing, high viscosity X X X X X 37441 1 oz. 37443 † 1 lb. 4307 <br />

CYANOACRYLATES<br />

4011 (SI) transparent/straw N M 100 -65 to 180 80 (D)* 200,000* 0.005 TP, TSP, ME, E Low viscosity, ideal on acidic substrates and in dry environments X X X X X X 18680 20 gram 18681 1 lb. 4011 <br />

4013 transparent/slight yellow N M 500 -65 to 180 65 (Barcol) 200,000* 0.010 TP, TSP, ME General purpose, gap filling X X X X 20268 20 gram 18013 1 lb. 4013 <br />

4014 transparent/slight yellow N M 3 -65 to 220 65 (Barcol) 200,000* 0.003 TP, TSP, ME General purpose for metal and plastic bonding X X X X 20269 20 gram 18014 1 lb. 4014 <br />

4031 (LO) transparent/pale yellow N M 1,300 -65 to 160 80 (D)* 200,000* 0.008 TP, TSP, ME Medium viscosity, minimizes need for ventilation, reduces frosted residue X X X 18682 20 gram 18683 1 lb. 4031 <br />

4061 (SI) transparent/straw N M 20 -65 to 180 80 (D)* 200,000* 0.004 TP, TSP, ME, E Wicking viscosity, ideal on acidic substrates and in dry environments X X X X X 18686 20 gram 18687 1 lb. 4061 <br />

4081 (LO) transparent/light yellow N M 5 -65 to 160 80 (D)* 200,000* 0.002 TP, TSP, ME Wicking viscosity, minimizes need for ventilation, reduces frosted residue X X X X X 18688 20 gram 18689 1 lb. 4081 <br />

4161 transparent/straw N M 1,500 -65 to 180 80 (D)* 200,000* 0.008 TP, TSP, ME Gap filling, excellent for various plastics X X 19743 20 gram 19744 1 lb. 4161 <br />

4206 (TR) colorless/pale yellow N M 375 -65 to 250 80 (D)* 120,200 0.005 TP, TSP, ME, E Impact resistant, withstands 250°F continuous for 2000 hours X X X 28628 20 gram 28629 † 1 lb. 4206 <br />

4541 (SI) clear/straw N M Gel -65 to 180 80 (D)* 200,000* 0.010 TP, TSP, ME, E Gel, excellent on acidic and porous substrates and in dry environments X 18690 20 gram 18691 200 gram 4541 <br />

4601 (LO) transparent/light yellow N M 50 -65 to 160 80 (D)* 200,000* 0.004 TP, TSP, ME Low viscosity, minimizes need for ventilation, reduces frosted residue X X X X 18692 20 gram 18693 1 lb. 4601 <br />

4851 clear N M 400 -65 to 125 85 (A) 86,275 0.006 TP, TSP, ME, E Flexible cyanoacrylate, low viscosity X X X X 37732 20 gram 37733 1 lb. 4851 <br />

4861 clear N M 4,000 -65 to 125 85 (A) 63,250 0.008 TP, TSP, ME, E Flexible cyanoacrylate, high viscosity X X X X 37708 20 gram 37711 1 lb. 4861 <br />

4981 transparent/pale yellow N M 500 -65 to 220 80 (D)* 200,000* 0.007 TP, TSP, ME, E Excellent thermal cycling and humidity resistance versus standard CAs X 18694 20 gram 18695 1 lb. 4981 <br />

EPOXIES<br />

3981 transparent/yellow Y H 5,300 -65 to 300 84 (D) 345,500 >0.50 TSP, ME, G, C Superior thermal, chemical and sterilization resistance, moderate viscosity X X 36766 30 ml 37297 1 liter 3981 <br />

3982 off-white Y H 8,000 -65 to 300 86 (D) 362,000 >0.50 TSP, ME, G, C Superior thermal, chemical and sterilization resistance, moderate viscosity X X 36767 30 ml 37298 1 liter 3982 <br />

3984 light grey Y H 25,500 -65 to 300 84 (D) 566,000 >0.50 TSP, ME, G, C Highest modulus, superior thermal, chemical and sterilization resistance X X 36768 30 ml 37299 † 1 liter 3984 <br />

M-21HP off-white N RT 37,000 (mixed) -65 to 300 80 (D) 226,000 >0.50 TP, TSP, E, ME, G, C High peel and shear strength, 20 minute worklife X X 30671 50 ml dual N/A M-21HP <br />

M-31CL colorless N RT 6,000 (mixed) -65 to 300 85 (D) 366,000 >0.50 TP, TSP, PC, ME, G, C Excellent impact resistant, 30 minute worklife X X 30673 50 ml dual 30674 † 200 ml dual M-31CL <br />

M-121HP amber/beige N RT 11,000 (mixed) -65 to 300 85 (D) 216,000 >0.50 TSP, PC,PVC,ME,G,C Excellent thermal shock resistance, ultra strength, 120 minute worklife X X 30680 50 ml dual N/A M-121HP <br />

URETHANES & UV SILICONES<br />

M-11FL water white clear N RT 3,800 (mixed) -65 to 250 45 (D) 1,860 >0.50 TP, TSP, PC, E, ME, G, C Urethane offering highly flexible bondlines, 10 minute worklife X 30678 50 ml dual N/A M-11FL <br />

5248 straw N UV, M 65,000 -65 to 400 25 (A) 110 at 100% elongation Max 0.25 E, ME,G UV silicone for bonding and sealing extruded and moldable silicones X X 19987 300 ml N/A 5248 <br />

CYANOACRYLATE ACCELERATORS & PRIMERS<br />

713 transparent/light amber N/A N/A 1 N/A N/A N/A N/A N/A Speeds fixture time for cyanoacrylates, may be pre or post applied X X X X 19889 1.75 fl. oz. N/A 713 <br />

7701 clear/colorless N/A N/A 3 N/A N/A N/A N/A TP, E Adhesion promotor for cyanoacrylates, for use on low energy plastics X X X X 19886 1.75 fl. oz. 19887 16 fl. oz. 7701 <br />

SI = Surface Insensitive<br />

LO = Low Odor/Low Bloom<br />

TR = Thermally Resistant<br />

H = Heat Cure<br />

M = Moisture<br />

RT = Room Temp.<br />

UV = Ultraviolet<br />

V = Visible<br />

KEY PRODUCT ATTRIBUTES TYPICAL ADHESIVE SELECTION PRODUCT ORDERING<br />

* Estimated<br />

** Light Cure products<br />

cured at 100 mW/cm 2<br />

for 10 seconds using a<br />

“D” bulb.<br />

C = Ceramics<br />

E = Elastomers<br />

G = Glass<br />

ME = Metal<br />

PC = Polycarbonate<br />

PVC = Polyvinylchloride<br />

TP = Thermoplastics<br />

TSP = Thermoset Plastics<br />

† Made to order items.


Henkel Resources Guide<br />

Visit us on the web at www.loctite.com/medical<br />

or call 1-800-LOCTITE (562-8483)<br />

BIOCOMPATIBILITY TESTING & CERTIFICATES OF COMPLIANCE:<br />

<strong>Loctite</strong> ® Medical Device Adhesives meet ISO-10993 Biocompatibility standards.<br />

All ISO-10993 Certificates of Compliance are available on the <strong>Loctite</strong> ® website and include the<br />

following tests:<br />

▲ Intracutaneous Injection<br />

▲ Systemic Injection<br />

▲ Muscle Implantation<br />

▲ Cytotoxicity (MEM Elution)<br />

▲ Hemocompatibility<br />

▲ Physicochemical<br />

Although Henkel has no specific regulatory requirement regarding the<br />

biocompatibility testing and revalidation of our medical device adhesives, as the industry<br />

leader we believe our triennial revalidation program is an important service to our customers in<br />

assuring continuity of compliance.<br />

TECHNICAL AND MATERIAL SAFETY DATA SHEETS:<br />

USA<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, call:<br />

1.800.323.5106<br />

For your nearest authorized <strong>Loctite</strong> ® brand<br />

distributor, to arrange an in-plant seminar or<br />

for technical product assistance, call:<br />

1.800.LOCTITE (1.800.562.8483)<br />

To place an order, call:<br />

1.800.243.4874<br />

Henkel Corporation<br />

1001 Trout Brook Crossing<br />

Rocky Hill, Connecticut 06067<br />

860.571.5100<br />

Fax: 860.571.5465<br />

Canada<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, for your nearest authorized<br />

<strong>Loctite</strong> ® brand distributor, to arrange an<br />

in-plant seminar, for technical product assistance<br />

or to place an order, call:<br />

1.800.263.5043 (within Canada)<br />

Henkel Canada Corporation<br />

2225 Meadowpine Blvd.<br />

Mississauga, Ontario L5N 7P2<br />

Tel: 905.814.6511<br />

Fax: 905.814.5391<br />

1.800.263.5043 (within Canada)<br />

Mexico<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, for your nearest authorized<br />

<strong>Loctite</strong> ® brand distributor, to arrange an<br />

in-plant seminar or for technical product<br />

assistance, call:<br />

01.800.90.181.00 (within Mexico)<br />

To place an order, call:<br />

01.800.84.994.12 (within Mexico)<br />

Henkel Capital, S.A. de C.V.<br />

Calzada de la Viga s/n Fracc. Los Laureles<br />

Loc. Tulpetlac, C.P. 55090<br />

Ecatepec de Morelos, Edo. de México<br />

Tel: 011.52.55.5836.1300<br />

Fax: 011.52.55.5787.9004<br />

Central America<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, for your nearest authorized<br />

<strong>Loctite</strong> ® brand distributor, to arrange an<br />

in-plant seminar, for technical product assistance<br />

or to place an order, call:<br />

506.277.4868<br />

Henkel Costa Rica Ltda.<br />

San Joaquin de Flores<br />

Heredía, Costa Rica<br />

Tel: 506.277.4800<br />

Fax: 506.277.4883<br />

South America<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, for your nearest authorized<br />

<strong>Loctite</strong> ® brand distributor, to arrange an in-plant<br />

seminar, for technical product assistance or to<br />

place an order, contact:<br />

Henkel Ltda.<br />

Rua Karl Huller, 136 – Jd.<br />

Canhema 09941-410<br />

Diadema/SP, Brazil<br />

Tel: 55.11.4075.8955<br />

Fax: 55.11.4075.8887<br />

0800.12.23.34 (within Brazil)<br />

Henkel Argentina S.A.<br />

Tte. Cnel. Magán 1990 – Sarandi<br />

(B1872HRN) Avellanda, Buenos Aires, Argentina<br />

Tel: 54.11.4001.0100<br />

Fax: 54.11.4205.3442<br />

0800.33.30213 (within Argentina)<br />

Henkel Chile Ltda.<br />

Av. Apoquindo 3355,<br />

Oficina 8 – 1º Piso<br />

Las Condes, Santiago, Chile<br />

Tel: 56.2.2333606<br />

Fax: 56.2.2341448<br />

800.212002 (within Chile)<br />

Henkel Colombiana S.A.<br />

Calle 17 No. 68-B-73,<br />

Bogotá D.C., Colombia<br />

Tel: 571.423.9000<br />

Fax: 571.425.1331<br />

01.800.01.14173 (within Colombia)<br />

INSTANT access to comprehensive technical and material safety data sheets is available on the<br />

<strong>Loctite</strong> ® website. Most are available in various languages. Technical data sheets are integrated<br />

with our material specifications and all products are tested on a batch to batch basis. Locate any<br />

<strong>Loctite</strong> ® technical data sheet using a product or item number, and safety data sheets using an<br />

item number.<br />

Henkel Venezolana S.A.<br />

Zona Industrial Pruinca<br />

Calle 2 Parcela 31 y 32<br />

Guacara – Edo Carabobo, Venezuela<br />

Tel: 5824.5560.2611<br />

Fax: 5824.5560.2660<br />

0800.436.5300 (within Venezuela)<br />

Henkel Corporation<br />

Engineering, Assembly & Maintenance Technologies<br />

1001 Trout Brook Crossing • Rocky Hill, CT 06067 U.S.A. • 800-562-8483 • www.henkel.us • www.loctite.com<br />

All trademarks listed in this selector guide are trademarks of Henkel Corporation, U.S.A.<br />

© Copyright 2004. Henkel Corporation. All rights reserved. 2196/LT-864H 11/04


USA<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, call:<br />

1.800.323.5106<br />

For your nearest authorized <strong>Loctite</strong> ® brand<br />

distributor, to arrange an in-plant seminar or<br />

for technical product assistance, call:<br />

1.800.LOCTITE (1.800.562.8483)<br />

To place an order, call:<br />

1.800.243.4874<br />

Henkel Corporation<br />

1001 Trout Brook Crossing<br />

Rocky Hill, Connecticut 06067<br />

860.571.5100<br />

Fax: 860.571.5465<br />

Canada<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, for your nearest authorized<br />

<strong>Loctite</strong> ® brand distributor, to arrange an<br />

in-plant seminar, for technical product assistance<br />

or to place an order, call:<br />

1.800.263.5043 (within Canada)<br />

Henkel Canada Corporation<br />

2225 Meadowpine Blvd.<br />

Mississauga, Ontario L5N 7P2<br />

Tel: 905.814.6511<br />

Fax: 905.814.5391<br />

1.800.263.5043 (within Canada)<br />

Mexico<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, for your nearest authorized<br />

<strong>Loctite</strong> ® brand distributor, to arrange an<br />

in-plant seminar or for technical product<br />

assistance, call:<br />

01.800.90.181.00 (within Mexico)<br />

To place an order, call:<br />

01.800.84.994.12 (within Mexico)<br />

Henkel Capital, S.A. de C.V.<br />

Calzada de la Viga s/n Fracc. Los Laureles<br />

Loc. Tulpetlac, C.P. 55090<br />

Ecatepec de Morelos, Edo. de México<br />

Tel: 011.52.55.5836.1300<br />

Fax: 011.52.55.5787.9004<br />

Central America<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, for your nearest authorized<br />

<strong>Loctite</strong> ® brand distributor, to arrange an<br />

in-plant seminar, for technical product assistance<br />

or to place an order, call:<br />

506.277.4868<br />

Henkel Costa Rica Ltda.<br />

San Joaquin de Flores<br />

Heredía, Costa Rica<br />

Tel: 506.277.4800<br />

Fax: 506.277.4883<br />

South America<br />

For your local <strong>Loctite</strong> ® brand Adhesives and<br />

Sealants Specialist, for your nearest authorized<br />

<strong>Loctite</strong> ® brand distributor, to arrange an in-plant<br />

seminar, for technical product assistance or to<br />

place an order, contact:<br />

Henkel Ltda.<br />

Rua Karl Huller, 136 – Jd.<br />

Canhema 09941-410<br />

Diadema/SP, Brazil<br />

Tel: 55.11.4075.8955<br />

Fax: 55.11.4075.8887<br />

0800.12.23.34 (within Brazil)<br />

Henkel Argentina S.A.<br />

Tte. Cnel. Magán 1990 – Sarandi<br />

(B1872HRN) Avellanda, Buenos Aires, Argentina<br />

Tel: 54.11.4001.0100<br />

Fax: 54.11.4205.3442<br />

0800.33.30213 (within Argentina)<br />

Henkel Chile Ltda.<br />

Av. Apoquindo 3355,<br />

Oficina 8 – 1º Piso<br />

Las Condes, Santiago, Chile<br />

Tel: 56.2.2333606<br />

Fax: 56.2.2341448<br />

800.212002 (within Chile)<br />

Henkel Colombiana S.A.<br />

Calle 17 No. 68-B-73,<br />

Bogotá D.C., Colombia<br />

Tel: 571.423.9000<br />

Fax: 571.425.1331<br />

01.800.01.14173 (within Colombia)<br />

Henkel Venezolana S.A.<br />

Zona Industrial Pruinca<br />

Calle 2 Parcela 31 y 32<br />

Guacara – Edo Carabobo, Venezuela<br />

Tel: 5824.5560.2611<br />

Fax: 5824.5560.2660<br />

0800.436.5300 (within Venezuela)<br />

Henkel Corporation<br />

Engineering, Assembly & Maintenance Technologies<br />

1001 Trout Brook Crossing • Rocky Hill, CT 06067 U.S.A. • 800-562-8483 • www.henkel.us • www.loctite.com<br />

All trademarks in this brochure, except where noted, are trademarks of Henkel Corporation, U.S.A. K-Resin is a reistered<br />

trademark of Chevron Phillips Chemical, Snap Swab is a reistered trademark of Medical Packaging Corporation, Dacron<br />

is a reistered trademark of DAK America. © Copyright 2004. Henkel Corporation. All rights reserved. 2196/LT-2399 6/04

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