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We provide cost-effective solutions that work for you.<br />
Why take a chance on anyone else?
Whether your medical device assembly requires an<br />
adhesive that is biocompatible and sterilizable – or one that<br />
meets a host of other performance characteristics – Henkel<br />
has the right adhesive for your application.<br />
Our adhesives have been specified by medical device<br />
manufacturers all over the world for over two decades.<br />
Our experience, products, and engineering services are second<br />
to none, with the world’s most diversified and comprehensive<br />
line of adhesives, dispensing equipment, and curing systems<br />
available anywhere. We offer over forty products for medical<br />
device assemblies requiring biocompatibility testing and<br />
hundreds of other products for applications not requiring<br />
such evaluation.<br />
Adhesives can provide design advantages, improve overall<br />
product performance, speed assembly time, and increase<br />
production efficiency and quality. <strong>Loctite</strong> ® adhesives combine<br />
all of these advantages, and more. When the total cost of<br />
a finished medical device is considered, adhesives are the<br />
most economical assembly choice. <strong>Loctite</strong> ® adhesives offer<br />
many benefits, including:<br />
▲ Structural Bonds<br />
▲ Ability to Bond Dissimilar and Difficult Substrates<br />
▲ Increased Throughput<br />
▲ Rapid Fixture and Overall Cure Times<br />
▲ Excellent Gap Filling Capability<br />
▲ Even Stress Distribution<br />
▲ Comprehensive Biocompatibility Testing
Our medical device adhesives cover a variety of chemistries, providing you with<br />
a wide range of choices and assembly solutions. We know one product won’t fit<br />
every design, and that’s why we continue to create and add new products, new<br />
chemistries, and even new technologies.<br />
All of our products are available in viscosities ranging from water-thin liquids to<br />
thixotropic gels and are compatible with common sterilization methods such as<br />
ethylene oxide, gamma radiation, electron beam, liquid sterilization, autoclave,<br />
and peroxide plasma.<br />
LIGHT CURING ADHESIVES<br />
Upon exposure to the appropriate light source, these onepart<br />
adhesives cure completely in seconds to form<br />
thermoset or thermoplastic polymers (depending on the<br />
chemistry) with excellent adhesion to a wide variety of<br />
substrates. Cure times from two to thirty seconds are typical.<br />
Light Curing Acrylics – These products offer the most<br />
extensive variety of properties of all light cure chemistries.<br />
Upon exposure to suitable light, acrylics produce tough,<br />
durable thermoset polymers. Cured properties range from<br />
hard and rigid to soft and flexible. Newer products cure<br />
under either UV or visible light sources and respond to low, medium, or high intensity light.<br />
Easily automated, fluorescent versions allow in-line detection of the adhesive.<br />
Light curing acrylics are used to assemble syringes, injectors, infusion sets, pressure<br />
transducers, drug delivery devices, IV sets, oxygenators, cardiotomy reservoirs, blood heat<br />
exchangers, hearing aids, anesthesia masks, and blood filters.<br />
Light Curing Cyanoacrylates – <strong>Loctite</strong> ® FlashCure ® light curing cyanoacrylates are well<br />
suited for applications where a secondary moisture cure is required, allowing the adhesive<br />
to cure completely in shadowed areas where light cannot reach. Exposure to low intensity<br />
UV or visible light provides tack-free surfaces in less than five<br />
seconds. These adhesives eliminate the need for solvent-borne<br />
accelerators and minimize stress cracking and blooming<br />
(a whiteness around the bondline), due to their “instant” fixturing.<br />
Light curing cyanoacrylates are ideal for the assembly of<br />
catheters, syringes, pressure transducers, orthopedic devices,<br />
infusion pumps, oxygen concentrators, blood gas analyzers,<br />
filters, as well as a number of other devices.<br />
Light Curing Silicones – When exposed to high intensity UV<br />
light, <strong>Loctite</strong> ® Nuva-Sil ® silicones cure into soft, flexible thermoset<br />
elastomers. Light curing silicones are excellent for sealing, gasketing and leakproofing, and<br />
are well suited for bonding silicone rubber.<br />
Light curing silicone applications include tracheal and endotracheal tubes, foley catheters,<br />
colostomy devices, and chest drainage tubes.
CYANOACRYLATE ADHESIVES<br />
These one-part adhesives cure in seconds at room temperature, forming slightly flexible to<br />
rigid thermoplastics. They are particularly suited for joining dissimilar substrates in almost any<br />
combination including polyolefins, thermoplastics, rubber, and metals. <strong>Loctite</strong> ® Prism ®<br />
cyanoacrylates are high performance instant adhesives designed for the most challenging<br />
applications. The Prism ® family includes flexible, toughened, low odor/low bloom, surface<br />
insensitive, and thermally resistant formulations.<br />
Cyanoacrylates are widely used to bond components in the assembly of blood pressure<br />
transducers, endoscopes, IV sets, infusion pumps, catheters, orthopedic devices, hearing<br />
aids, cast boots, and diagnostic imaging equipment.<br />
CYANOACRYLATE ACCELERATORS AND PRIMERS<br />
Accelerators speed the cure of cyanoacrylates and are used to reduce fixture and cure times,<br />
or to cure fillets on bondlines and/or exposed adhesive. They can be applied to a substrate<br />
prior to the application of cyanoacrylate adhesive or they can be sprayed over a drop or<br />
fillet to initiate a rapid cure. Primers enable the cyanoacrylate to form strong bonds with<br />
polyolefins and other difficult plastics such as acetal resins. Depending on the plastic, bond<br />
strengths up to 20 times the unprimed bond strength may be achieved.<br />
EPOXY ADHESIVES<br />
<strong>Loctite</strong> ® Hysol ® epoxies provide high peel and shear strength on a wide variety of plastics<br />
and metals. When cured, these crosslinking thermoset plastics offer superior thermal and<br />
chemical resistance, as well as high cohesive strength and minimal shrinkage. Hysol ®<br />
two-part systems are packaged in side-by-side cartridges, allowing them to be dispensed<br />
as easily as any one part system.<br />
Our new single component, heat cure formulas are excellent for bonding metals to a wide<br />
variety of plastics, providing superior pull strength when joining cannulae to hubs or syringes.<br />
Epoxies are commonly used on endoscopes, catheters, artherectomy devices, blood heat<br />
exchangers, syringes, and dental, surgical and orthopedic instruments.<br />
POLYURETHANE ADHESIVES<br />
<strong>Loctite</strong> ® Hysol ® urethanes are ideal for bonding metals, plastics, glass, and other<br />
substrates. Designed for potting and encapsulating applications, these two-part, room<br />
temperature curing products provide excellent peel and shear strength. They are ideal for<br />
opaque substrates that require high flexibility.<br />
Urethanes are commonly used in potting applications on filters, kidney dialyzers,<br />
blood heat exchangers, and catheters.
CATHETER SAFETY INCREASED<br />
A thermal dilution catheter manufacturer<br />
requested assistance for bonding a latex<br />
balloon to a rigid, multi-lumen PVC tube. The<br />
catheter is inserted into a major vein near the<br />
heart to take blood samples, administer fluids,<br />
and monitor blood pressure and body<br />
temperature. The transducer must endure<br />
temperatures ranging from freezing to 110°F,<br />
while the balloon must withstand pressures up<br />
to 110 lbs. After bonding, the balloon is inflated<br />
fifty times to check bond durability.<br />
TOXIC SOLVENTS<br />
ELIMINATED<br />
<strong>Loctite</strong> ® 4014 cyanoacrylate<br />
secures a latex balloon to<br />
rigid PVC tubing.<br />
<strong>Loctite</strong> ® 4014 cyanoacrylate was selected on the balloon<br />
bond, for its low viscosity, thermal resistance and controlled<br />
setting time. This allowed time to assemble and place the<br />
balloon precisely. The customer reports that the adhesive<br />
works so well that “the balloon ruptures before the adhesive<br />
fails.”<br />
<strong>Loctite</strong> ® 4011 replaced solvent<br />
bonding in this PVC tube to<br />
copolymer fistula assembly.<br />
VETERINARY DEVICE SECURED<br />
Animal drugs for livestock management<br />
and the introduction of new vaccines and<br />
drug treatments have led to new delivery<br />
techniques in veterinary device technology.<br />
Since the FDA does not require the same<br />
standards for animal devices as those<br />
required for medical devices intended for<br />
humans, manufacturers may use nonmedical<br />
products. Their responsibility is to<br />
assure that the animal medical device is<br />
<strong>Loctite</strong> ® 406, an industrial cyanoacrylate, joins<br />
safe, effective, and properly labeled.<br />
polypropylene to polypropylene, on this veterinary<br />
syringe, increasing product quality and safety.<br />
Most syringes used for animal injections<br />
are made of solvent resistant polypropylene (PP). Because of the difficulty in joining PP, snap<br />
fittings are frequently used to connect tubes and barrels. However, the soft and pliable nature<br />
of PP often results in poor performance or joint failures. Because livestock is very expensive,<br />
if a syringe breaks during an injection it could mean the loss of an expensive drug, as well as<br />
internal injury to the animal, should the broken section be swallowed by a valuable<br />
racehorse, for example.<br />
To permanently connect the components, <strong>Loctite</strong> ® 406, a low viscosity adhesive, was<br />
selected for its ability to bond difficult substrates. <strong>Loctite</strong> ® 770 polyolefin primer was applied<br />
to the PP, prior to applying the cyanoacrylate, to obtain maximum bond strength. The bonded<br />
parts met every drug resistance and strength test required by the manufacturer.<br />
Note: For medical devices intended for humans, <strong>Loctite</strong> ® 4061 adhesive and 7701 primer<br />
are recommended, as they comply with extensive biocompatibility testing.<br />
A manufacturer of a device used in dialysis<br />
machines to withdraw and return blood had<br />
a production line shut down. The problem:<br />
one vendor had supplied out-of-tolerance<br />
parts, and the solvent used for bonding<br />
could not fill the excessive gap. Their PVC<br />
tubing supplier also made a substitution,<br />
creating additional assembly problems.<br />
The assembly process used solvent welding,<br />
a mixture of 90% methylene chloride and<br />
10% cyclohexanone, to join a flexible PVC<br />
tube to a copolymer elastomer (TPE). The<br />
parts were joined by slip fit, with a gap of<br />
.002", using a dip and assemble technique.<br />
The assembled product had to meet a 20-25<br />
psi burst test and a 15 lb. pull test.<br />
<strong>Loctite</strong> ® 4011, a surface insensitive<br />
cyanoacrylate, was specified. It filled the<br />
gap and had enough strength to pass the<br />
burst and pull tests with ease. Since the<br />
manufacturer already used <strong>Loctite</strong> ® 4011<br />
in another area of the plant, making the<br />
switch was easy. Production goals were<br />
met, inventory was used, product quality<br />
was assured, and a potentially troublesome<br />
toxic solvent was eliminated.
SOLVENTS AND STRESS<br />
CRACKING ELIMINATED<br />
This soft, flexible catheter uses a “peel<br />
away,” splitable needle introducer, a unique<br />
catheter insertion system for fragile veins.<br />
After insertion, the needle’s wing assembly<br />
is split apart and discarded, eliminating the<br />
need to repeatedly restick the patient.<br />
BOND STRENGTH INCREASES<br />
5X ON SAFETY SYRINGES<br />
<strong>Loctite</strong> ® 3211 improves product<br />
quality, reduces rejects and<br />
eliminates toxic solvent fumes during<br />
assembly of this micro-catheter.<br />
STRONG, FLEXIBLE<br />
BONDS ACHIEVED<br />
<strong>Loctite</strong> ® Prism ® 410 is used to<br />
lock the stainless steel threaded<br />
fastener into position during<br />
the customized fitting of this<br />
prosthesis.<br />
FOUR-SECOND CURE<br />
DOUBLES PRODUCTION<br />
The manufacturer was dissatisfied with the<br />
process used to bond the stainless steel<br />
needle halves to lightly-tinted polycarbonate<br />
wings. A “solvent cocktail,” made by<br />
combining a plastic, such as PVC pellets,<br />
and adding solvent, to make a “glue,” was<br />
being used. Formulation inconsistency, stress cracking, and<br />
toxic solvent fumes were growing concerns.<br />
The solution, <strong>Loctite</strong> ® 3211 was specified along with a<br />
<strong>Loctite</strong> ® light cure chamber. The combination proved superior<br />
in every way – eliminating stress cracking while reducing<br />
rejects due to the solvent cocktail’s inconsistencies.<br />
This lower limb prosthetic device manufacturer builds<br />
prostheses made of carbon fiber, a material known for its<br />
superior strength, flexibility, and imperviousness to the<br />
elements as well as corrosion and stress. They wanted to<br />
provide amputees with proportional response, an active heel<br />
with natural ankle motion and a 95% energy return that<br />
actually powers the wearer through each step.<br />
<strong>Loctite</strong> ® 410 Prism ® , a black, rubber toughened industrial<br />
cyanoacrylate, provides the flexibility required to maintain<br />
appropriate fastener torque on the stainless steel fastener<br />
used in customizing the fit of these prostheses. The product is<br />
easily visible and removable, and is applied without activators<br />
or primers. <strong>Loctite</strong> ® 277 industrial threadlocker is used for the<br />
larger 1" pre-assembled fasteners to prevent loosening while in<br />
use. This customer uses <strong>Loctite</strong> ® products throughout their<br />
manufacturing facility, to provide strong, flexible bonds on their<br />
line of products.<br />
<strong>Loctite</strong> ® 3051 bonds K-Resin ® to stainless<br />
steel cannulae in dental syringes,<br />
increasing product quality. Ready for<br />
injection (left), and K-Resin guard covering<br />
needle after injection (right).<br />
This syringe, with pre-attached needles, is designed to<br />
prevent accidental needlesticks in the dental industry.<br />
An anesthesia cartridge is loaded into the K-Resin ®<br />
body assembly, which penetrates the back of the<br />
needle, allowing the anesthesia to flow into the<br />
syringe. After the injection is made, a second guard<br />
slides down over the needle, fully enclosing it.<br />
Traditional dental syringes involve multiple chances to<br />
get stuck with “screw-on” needles.<br />
Henkel was called upon in the design stage to analyze<br />
the application, which involved bonding a stainless<br />
steel cannula to a K-Resin ® syringe body. Heat cure<br />
epoxies were evaluated, but the heat caused the<br />
viscosity of the epoxy to decrease, resulting in<br />
occluded needles and misaligned parts. The customer<br />
required consistency, automation, and a minimum pull<br />
strength of 4.4 lbs.<br />
<strong>Loctite</strong> ® 3051 was evaluated and proved superior on<br />
the substrates. It was easily automated and eliminated<br />
heat cures and migrating epoxy issues. Cure time was<br />
4-5 seconds under a <strong>Loctite</strong> ® high intensity light cure<br />
conveyor. Production and product quality increased<br />
significantly, allowing the customer to achieve 4-5<br />
times greater pull strength, delivering 20 lbs. versus<br />
the 4.4 lbs. required.<br />
A manufacturer wanted a better way to assemble anesthesia masks in order to double production. The<br />
substrates they were bonding were rigid cones to flexible, highly plasticized PVC face cushions. The masks<br />
were assembled with a cyanoacrylate that required 9 seconds to fixture and several hours to fully cure.<br />
Some brittleness and blooming during and after cure was experienced, with rework and rejections running<br />
high. A peel test demonstrating substrate failure was required, and no oxygen leakage could be exhibited<br />
from the mask after bonding.<br />
Rigid to highly plasticized PVC is<br />
bonded easily with <strong>Loctite</strong> ® 3341<br />
on anesthesia masks.<br />
<strong>Loctite</strong> ® 3341 proved to be the superior alternative, passing all tests and requiring only 4 seconds for<br />
complete cure under a <strong>Loctite</strong> ® medium-intensity light cure conveyor. This enabled the customer to not only<br />
double production by adding another shift, it also presented a significant cost savings over their prior<br />
cyanoacrylate usage.
ENVIRONMENTAL CONCERNS<br />
ELIMINATED FOR<br />
COLLECTION RESERVOIR<br />
LIGHT CURE TECHNOLOGY<br />
IMPROVES APPEARANCE AND<br />
SPEEDS PRODUCTION<br />
Hearing aid manufacturers have long relied on adhesives for the assembly<br />
of various hearing aid components including face plates and receiver<br />
components. Recent advances in light curing technology have allowed for<br />
increased throughput and reliability.<br />
<strong>Loctite</strong> ® Flashcure ® cyanoacrylates are single component light curing<br />
adhesives. With exposure to low intensity light, the Flashcure ® products<br />
cure in seconds offering strong faceplate and componentry bonds. The<br />
need for solvent-based cyanoacrylate accelerators is eliminated and the<br />
potential for blooming (a whiteness around the bond line) is reduced.<br />
<strong>Loctite</strong> ® 3211 eliminates solvents and<br />
provides structural strength for<br />
collection reservoir.<br />
A leading manufacturer of blood collection and<br />
processing systems used solvents such as<br />
methylene chloride for bonding various device<br />
components and subassemblies. OSHA and the<br />
EPA were encouraging industries to move away<br />
from using solvents, and this device manufacturer<br />
particularly wanted to eliminate their use of<br />
methylene chloride. Since the devices were made<br />
of glass-like plastics, their engineers required<br />
clear bonds with no stress cracking or crazing.<br />
The collection reservoir, a disposable device<br />
used to clean and return blood to patients during<br />
various surgical procedures, consists of a clear,<br />
polycarbonate lid assembly joined to a<br />
polycarbonate bucket. Environmental concerns<br />
and issues associated with solvent bonding were<br />
eliminated with a new tongue and groove design<br />
and with <strong>Loctite</strong> ® 3211 – a safer, faster and<br />
more consistent bonding choice. <strong>Loctite</strong> ® 3211<br />
light curing adhesive provided the aesthetic<br />
bondline the manufacturer wanted. It also<br />
provided the structural strength that the<br />
collection reservoir manufacturer needed to<br />
maintain a competitive edge in the marketplace.<br />
<strong>Loctite</strong> ® Nuva-Sil ® silicones are single component, light/moisture curing<br />
adhesives/sealants. The rapid cure with exposure to high intensity light<br />
makes the dual curing silicones the products of choice for the bonding of<br />
the receiver tube to the receiver, and the bonding of the receiver tube to<br />
the shell for hearing aid shell fabrication.<br />
<strong>Loctite</strong> ® customdesigned<br />
needle<br />
specimens are used<br />
to verify adhesive<br />
application and<br />
performance.<br />
ON-PART DETECTION ENSURES<br />
QUALITY AND RELIABILITY<br />
<strong>Loctite</strong> ® light cure products<br />
allow for the rapid and reliable<br />
assembly of hearing aids.<br />
Adhesives are universally used for bonding cannulae to hubs in needle assemblies. It is<br />
critical that this joint is well bonded and sealed to prevent fluids such as blood or medicine<br />
from leaking. It is also essential that the position of the cannula remains fixed.<br />
All <strong>Loctite</strong> ® needle bonding adhesives are fluorescent to facilitate final inspection of the<br />
adhesive joint, ensuring that the adhesive is not only present but also that the adhesive<br />
has flowed into the bond joint correctly. The <strong>Loctite</strong> ® Fluorescent Detector is used to<br />
perform a present or not present inspection. If more precision is desired, the<br />
fluorescence can be monitored using a vision system, albeit at much higher expense.<br />
Henkel offers the most extensive line of needle bonding adhesives. These<br />
UV/visible acrylic and/or one-part epoxy products are specifically designed for<br />
the assembly of stainless steel cannulae to a variety of hub materials including<br />
polycarbonate, acrylic, ABS, and polypropylene. The wide range of adhesives<br />
includes viscosity, environmental, substrate and performance variations to ensure<br />
that there is a product to meet any needle bonding application requirement.<br />
INNOVATIVE DEVICE PACKAGING SOLVES SAFETY HAZARD<br />
For years, a swab device in combination with a reagent filled glass ampule has been used for various diagnostic<br />
tests. Following sample collection, the glass ampule was broken releasing the test reagent for use in the analysis.<br />
Problems with the procedure included the possibility that glass shards could cut the technician, clog the dropper<br />
tube or get into the reagent. The development of an innovative package allowed for increased safety and a<br />
patented product offering the manufacturer a competitive advantage in a very large market.<br />
The new product was designated the SnapSwab and consisted of a Dacron ® swab tip on a polystyrene shaft<br />
encased in a polyethylene tube. In use, a quick snap of the swab shaft releases the reagent and the swab is ready<br />
for use. It was necessary to reliably attach the swab to the inside of the tube and ensure the entire assembly be<br />
leak proof.<br />
<strong>Loctite</strong> ® 3311 offers adhesion to<br />
various swab substrates, resulting<br />
in a safer and more reliable device.<br />
<strong>Loctite</strong> ® 3311, a single component light cure acrylic adhesive, was the material of choice for the new swab<br />
device. Rapid, semi-automated processing, and high adhesion to the various swab substrates resulted in a device<br />
that was safe, convenient, dependable, and inexpensive.
DISPENSING<br />
<strong>Loctite</strong> ® 3211 Light Cure Acrylic is dispensed<br />
onto a polycarbonate fluid reservoir.<br />
Henkel offers a complete line of dispensing, curing and process monitoring<br />
equipment designed specifically for use with our medical device adhesives.<br />
Our dispensing equipment options range from manual and semi-automatic to<br />
fully automatic systems, along with a complete line of accessories, such as<br />
needles, nozzles, and syringes. Our dispensing technology enables customers<br />
to apply drops or beads of adhesives, making precise application of <strong>Loctite</strong> ®<br />
products economical, fast, and clean.<br />
We offer custom engineered systems for<br />
turnkey integration in high speed assembly<br />
processes. If your future production plans<br />
include significant growth, Henkel can even<br />
show you the advantages of installing a<br />
flexible system that can grow with your<br />
changing needs.<br />
CURING<br />
Anesthesia masks are cured following assembly<br />
with a flexible <strong>Loctite</strong> ® light cure acrylic adhesive.<br />
A variety of light curing systems, ranging<br />
from portable curing wands to modular flood<br />
chambers, and benchtop conveyors, are<br />
available. All of our light cure equipment is<br />
engineered to match the spectral output of<br />
our range of light curing adhesives. As a<br />
manufacturer of both the adhesive and curing<br />
equipment, we understand the chemistry and the process needed to cure our<br />
products properly, so you can be assured of obtaining the maximum bond<br />
strength and cure speeds. Matching the adhesive to the correct curing system<br />
will optimize your assembly process and help you attain the fastest, most<br />
consistent cures. We offer a full line of accessories, including radiometers,<br />
replacement bulbs, and UV safety glasses.<br />
Henkel’s state-of-the-art detection systems allow for real time process<br />
monitoring of dispense cycles. Whether you are trying to determine the<br />
presence of adhesive via fluorescence detection, or the amount of adhesive<br />
dispensed from an individual dispense nozzle, Henkel has the system that will<br />
get the job done with high degrees of precision and reliability.<br />
Henkel also provides engineering resources to assist customers in developing<br />
manufacturing and assembly processes which effectively integrate on-line<br />
dispensing and curing equipment. Rental and repair services are also offered,<br />
affording customers the opportunity to fully evaluate a process and equipment<br />
prior to making a capital investment.<br />
PROCESS MONITORING<br />
The <strong>Loctite</strong> ® Fluorescence Detector is used<br />
to verify adhesive application on<br />
needle assemblies.<br />
For more information on our complete line of dispensing, curing and<br />
process monitoring equipment, visit us at equipment.loctite.com
Our goal is to become your adhesive consultant. Whether you need a quick product<br />
recommendation, or a full-blown turnkey process, Henkel Engineering Services can provide the<br />
right solution. Our skilled engineers have years of combined experience developing hundreds of<br />
solutions for medical device manufacturers. Consult with Henkel and gain access to:<br />
▲ The best product and process solution for your specific application<br />
▲ Products tested and in compliance with our ISO-10993 Biocompatibility Test<br />
Program – the most comprehensive in the industry<br />
▲ Highly trained and skilled specialists with the know-how to consult,<br />
troubleshoot, and solve problems<br />
▲ On-site product and application training and support<br />
▲ State-of-the-art parts testing and evaluation facilities to simulate a<br />
wide range of environments<br />
Whether we are reducing your assembly costs, providing design and<br />
application assistance, or increasing the reliability of your process, Henkel<br />
is dedicated to earning your trust. Count on Henkel to be your sole<br />
source for all of your medical device applications.<br />
Henkel offers training programs that provide additional support to device<br />
manufacturers around the globe. Training continues after the seminar: you are linked to<br />
a network of informational sources including adhesive design guides, research data, and technical reports.<br />
Advanced Medical Device Adhesive Workshops: These unique, fully integrated, four to seven hour<br />
programs are taught by Henkel engineering and technical representatives who have years of experience<br />
providing solutions to medical device manufacturers on design and assembly challenges. Presenters will<br />
review a range of issues specifically related to the medical device industry. Attendees will benefit from<br />
hands-on demonstrations of adhesives and equipment.<br />
For dates and locations of up-coming Advanced Medical Device Adhesive Workshops, log onto our<br />
website at www.loctite.com/medical.<br />
On-Site Technology Seminars: A training program customized to your needs. Select from a menu of seven of<br />
the most requested medical device adhesive topics or request a customized seminar to meet your specific<br />
requirements. The course will be presented on-site and will include instruction, hands-on demos, samples,<br />
and technical guides.<br />
For more information on the On-Site Seminar program, contact Henkel at 1-800-LOCTITE.<br />
We support our customers with a service program that is unmatched by<br />
others in the industry. It’s what sets Henkel apart.
<strong>Loctite</strong> ® Brand Appearance Fluorescent Cure Method Viscosity, cP Temperature Shore Hardness Modulus (psi) Cure Depth** Substrates Product Features Needle Catheters Reservoir Respiratory Sutures Tube Sets Endoscopes Hearing Item Package Item Package Product<br />
Product Range (°F) (inches) Bonding Assemblies Aids Number Size Number Size<br />
LIGHT CURE ACRYLICS<br />
3201 transparent/hazy N UV, V 4,000 -65 to 300 59 (D) 43,000 0.05 PC, TP, ME, G Highly flexible PC adhesive, minimal stress cracking X 19727 25 ml 19728 1 liter 3201 <br />
3211 transparent/hazy N UV, V 10,000 (thixotropic) -65 to 300 51 (D) 30,000 0.06 PC, TP, ME, G Non-migrating, very flexible PC adhesive, minimal stress cracking X 19730 25 ml 19731 † 1 liter 3211 <br />
3301 transparent N UV, V 150 -65 to 300 69 (D) 107,000 0.10 PVC, PC, TP, ME, G Slightly flexible, excellent on PVC X X 19733 25 ml 19734 1 liter 3301 <br />
3311 transparent N UV, V 300 -65 to 300 64 (D) 97,000 0.09 PVC, PC, TP, ME, G Flexible, excellent on PVC and most thermoplastics X 19736 25 ml 19737 1 liter 3311 <br />
3321 transparent N UV, V 5,000 -65 to 300 53 (D) 37,000 0.08 PVC, PC, TP, ME, G Flexible, ideal for thermoplastics X 19739 25 ml 19740 1 liter 3321 <br />
3341 transparent/light yellow Y UV, V 450 -65 to 300 27 (D) 36,000 0.12 PVC, TP Excellent on highly plasticized PVC and other difficult-to-bond substrates X X X X X 23792 25 ml 23440 1 liter 3341 <br />
3345 clear/light straw N UV 1,500 -65 to 260 70 (D) 180,000 0.08 G, ME Excellent for glass to metal X 33417 25 ml 30688 † 1 liter 3345 <br />
3381 translucent/colorless N UV 5,000 -65 to 300 72 (A) 2,670 0.10 TP, TSP Extremely flexible, thermal cycling resistant X 25785 25 ml 24690 † 1 liter 3381 <br />
3911 transparent/hazy Y UV, V 100 -65 to 300 65 (D) 20,250 0.07 G, ME, TP Low viscosity, low moisture absorption X X 36536 25 ml 36537 † 1 liter 3911 <br />
3912 transparent/hazy Y UV, V 6,300 -65 to 300 60 (D) 20,750 0.07 G, ME, TP Medium viscosity, low moisture absorption X X 36539 25 ml 36540 1 liter 3912 <br />
3913 transparent Y UV 8,500 -65 to 300 64 (D) 31,500 0.09 G, ME, TP Highly fluorescent X X 36791 25 ml 36804 1 liter 3913 <br />
3921 transparent/hazy Y UV, V 150 -65 to 300 67 (D) 122,750 0.08 PVC, PC, TP, ME G Highly fluorescent, superior sterilization resistance X X X 36484 25 ml 36485 1 liter 3921 <br />
3922 transparent/hazy Y UV, V 300 -65 to 300 66 (D) 91,500 0.12 PVC, PC, TP, ME, G Superior sterilization resistance, excellent adhesion to PC X X 32083 25 ml 32047 † 1 liter 3922 <br />
3924 transparent/hazy Y UV, V 1,100 -65 to 300 60 (D) 41,100 0.10 PVC, PC, TP, ME, G Superior sterilization resistance, excellent adhesion to various TSP X X X X 36488 25 ml 36489 1 liter 3924 <br />
3926 transparent/hazy Y UV, V 5,500 -65 to 300 57 (D) 20,700 0.10 PVC, PC, TP, ME, G Highly fluorescent, superior sterilization resistance X X 36492 25 ml 36493 1 liter 3926 <br />
3933 transparent/hazy Y UV, V 3,250 -65 to 300 57 (D) 47,000 0.04 PC, TP, ME, G Excellent on PC and other TP X X 32084 25 ml 32040 † 1 liter 3933 <br />
3936 transparent/hazy Y UV, V 10,000 -65 to 300 55 (D) 24,500 0.08 PC, TP, ME, G Highly flexible, excellent on PC and other TP X 32304 25 ml 32037 † 1 liter 3936 <br />
3941 transparent/hazy Y UV, V 480 -65 to 300 74 (D) 184,000 0.06 G, ME, TP, TSP Highly fluorescent, rapid tack-free curing X X 36437 25 ml 36476 1 liter 3941 <br />
3942 transparent/hazy Y UV, V 1,100 -65 to 300 76 (D) 142,900 0.11 G, ME, TP, TSP High performance, rapid tack-free curing X X 36483 25 ml 36481 1 liter 3942 <br />
3943 transparent/hazy Y UV, V 6,000 -65 to 300 69 (D) 64,000 0.12 G, ME, TP, TSP Tough, superior tack-free curing X X 36480 25 ml 36478 1 liter 3943 <br />
3944 fluorescent/pale yellow Y UV, V 5,000 -65 to 300 50 (D)* 57,000 0.15 PVC, PC, TP, ME, G Superior surface curing, very flexible X 38210 25 ml 38212 † 1 liter 3944 <br />
3971 transparent Y UV, V 300 -65 to 300 71 (D) 95,000 0.16 PVC, TP, ME Superior tack-free curing, low viscosity X X X X 36792 25 ml 36805 1 liter 3971 <br />
3972 transparent/hazy Y UV, V 4,500 -65 to 300 68 (D) 66,750 0.25 PVC, TP, ME Superior tack-free curing, moderate viscosity X X X X X 36294 25 ml 36295 1 liter 3972 <br />
LIGHT CURE CYANOACRYLATES<br />
4306 light amber/light green Y UV, V, M 20 -65 to 180 82 (D) 250,700 0.15 TP, PC, E, ME Rapid tack-free surface and shadow curing, low viscosity X X X X X X 37439 1 oz. 37442 † 1 lb. 4306 <br />
4307 light amber/light green Y UV, V, M 900 -65 to 180 82 (D) 262,900 0.17 TP, PC, E, ME Rapid tack-free surface and shadow curing, high viscosity X X X X X 37441 1 oz. 37443 † 1 lb. 4307 <br />
CYANOACRYLATES<br />
4011 (SI) transparent/straw N M 100 -65 to 180 80 (D)* 200,000* 0.005 TP, TSP, ME, E Low viscosity, ideal on acidic substrates and in dry environments X X X X X X 18680 20 gram 18681 1 lb. 4011 <br />
4013 transparent/slight yellow N M 500 -65 to 180 65 (Barcol) 200,000* 0.010 TP, TSP, ME General purpose, gap filling X X X X 20268 20 gram 18013 1 lb. 4013 <br />
4014 transparent/slight yellow N M 3 -65 to 220 65 (Barcol) 200,000* 0.003 TP, TSP, ME General purpose for metal and plastic bonding X X X X 20269 20 gram 18014 1 lb. 4014 <br />
4031 (LO) transparent/pale yellow N M 1,300 -65 to 160 80 (D)* 200,000* 0.008 TP, TSP, ME Medium viscosity, minimizes need for ventilation, reduces frosted residue X X X 18682 20 gram 18683 1 lb. 4031 <br />
4061 (SI) transparent/straw N M 20 -65 to 180 80 (D)* 200,000* 0.004 TP, TSP, ME, E Wicking viscosity, ideal on acidic substrates and in dry environments X X X X X 18686 20 gram 18687 1 lb. 4061 <br />
4081 (LO) transparent/light yellow N M 5 -65 to 160 80 (D)* 200,000* 0.002 TP, TSP, ME Wicking viscosity, minimizes need for ventilation, reduces frosted residue X X X X X 18688 20 gram 18689 1 lb. 4081 <br />
4161 transparent/straw N M 1,500 -65 to 180 80 (D)* 200,000* 0.008 TP, TSP, ME Gap filling, excellent for various plastics X X 19743 20 gram 19744 1 lb. 4161 <br />
4206 (TR) colorless/pale yellow N M 375 -65 to 250 80 (D)* 120,200 0.005 TP, TSP, ME, E Impact resistant, withstands 250°F continuous for 2000 hours X X X 28628 20 gram 28629 † 1 lb. 4206 <br />
4541 (SI) clear/straw N M Gel -65 to 180 80 (D)* 200,000* 0.010 TP, TSP, ME, E Gel, excellent on acidic and porous substrates and in dry environments X 18690 20 gram 18691 200 gram 4541 <br />
4601 (LO) transparent/light yellow N M 50 -65 to 160 80 (D)* 200,000* 0.004 TP, TSP, ME Low viscosity, minimizes need for ventilation, reduces frosted residue X X X X 18692 20 gram 18693 1 lb. 4601 <br />
4851 clear N M 400 -65 to 125 85 (A) 86,275 0.006 TP, TSP, ME, E Flexible cyanoacrylate, low viscosity X X X X 37732 20 gram 37733 1 lb. 4851 <br />
4861 clear N M 4,000 -65 to 125 85 (A) 63,250 0.008 TP, TSP, ME, E Flexible cyanoacrylate, high viscosity X X X X 37708 20 gram 37711 1 lb. 4861 <br />
4981 transparent/pale yellow N M 500 -65 to 220 80 (D)* 200,000* 0.007 TP, TSP, ME, E Excellent thermal cycling and humidity resistance versus standard CAs X 18694 20 gram 18695 1 lb. 4981 <br />
EPOXIES<br />
3981 transparent/yellow Y H 5,300 -65 to 300 84 (D) 345,500 >0.50 TSP, ME, G, C Superior thermal, chemical and sterilization resistance, moderate viscosity X X 36766 30 ml 37297 1 liter 3981 <br />
3982 off-white Y H 8,000 -65 to 300 86 (D) 362,000 >0.50 TSP, ME, G, C Superior thermal, chemical and sterilization resistance, moderate viscosity X X 36767 30 ml 37298 1 liter 3982 <br />
3984 light grey Y H 25,500 -65 to 300 84 (D) 566,000 >0.50 TSP, ME, G, C Highest modulus, superior thermal, chemical and sterilization resistance X X 36768 30 ml 37299 † 1 liter 3984 <br />
M-21HP off-white N RT 37,000 (mixed) -65 to 300 80 (D) 226,000 >0.50 TP, TSP, E, ME, G, C High peel and shear strength, 20 minute worklife X X 30671 50 ml dual N/A M-21HP <br />
M-31CL colorless N RT 6,000 (mixed) -65 to 300 85 (D) 366,000 >0.50 TP, TSP, PC, ME, G, C Excellent impact resistant, 30 minute worklife X X 30673 50 ml dual 30674 † 200 ml dual M-31CL <br />
M-121HP amber/beige N RT 11,000 (mixed) -65 to 300 85 (D) 216,000 >0.50 TSP, PC,PVC,ME,G,C Excellent thermal shock resistance, ultra strength, 120 minute worklife X X 30680 50 ml dual N/A M-121HP <br />
URETHANES & UV SILICONES<br />
M-11FL water white clear N RT 3,800 (mixed) -65 to 250 45 (D) 1,860 >0.50 TP, TSP, PC, E, ME, G, C Urethane offering highly flexible bondlines, 10 minute worklife X 30678 50 ml dual N/A M-11FL <br />
5248 straw N UV, M 65,000 -65 to 400 25 (A) 110 at 100% elongation Max 0.25 E, ME,G UV silicone for bonding and sealing extruded and moldable silicones X X 19987 300 ml N/A 5248 <br />
CYANOACRYLATE ACCELERATORS & PRIMERS<br />
713 transparent/light amber N/A N/A 1 N/A N/A N/A N/A N/A Speeds fixture time for cyanoacrylates, may be pre or post applied X X X X 19889 1.75 fl. oz. N/A 713 <br />
7701 clear/colorless N/A N/A 3 N/A N/A N/A N/A TP, E Adhesion promotor for cyanoacrylates, for use on low energy plastics X X X X 19886 1.75 fl. oz. 19887 16 fl. oz. 7701 <br />
SI = Surface Insensitive<br />
LO = Low Odor/Low Bloom<br />
TR = Thermally Resistant<br />
H = Heat Cure<br />
M = Moisture<br />
RT = Room Temp.<br />
UV = Ultraviolet<br />
V = Visible<br />
KEY PRODUCT ATTRIBUTES TYPICAL ADHESIVE SELECTION PRODUCT ORDERING<br />
* Estimated<br />
** Light Cure products<br />
cured at 100 mW/cm 2<br />
for 10 seconds using a<br />
“D” bulb.<br />
C = Ceramics<br />
E = Elastomers<br />
G = Glass<br />
ME = Metal<br />
PC = Polycarbonate<br />
PVC = Polyvinylchloride<br />
TP = Thermoplastics<br />
TSP = Thermoset Plastics<br />
† Made to order items.
Henkel Resources Guide<br />
Visit us on the web at www.loctite.com/medical<br />
or call 1-800-LOCTITE (562-8483)<br />
BIOCOMPATIBILITY TESTING & CERTIFICATES OF COMPLIANCE:<br />
<strong>Loctite</strong> ® Medical Device Adhesives meet ISO-10993 Biocompatibility standards.<br />
All ISO-10993 Certificates of Compliance are available on the <strong>Loctite</strong> ® website and include the<br />
following tests:<br />
▲ Intracutaneous Injection<br />
▲ Systemic Injection<br />
▲ Muscle Implantation<br />
▲ Cytotoxicity (MEM Elution)<br />
▲ Hemocompatibility<br />
▲ Physicochemical<br />
Although Henkel has no specific regulatory requirement regarding the<br />
biocompatibility testing and revalidation of our medical device adhesives, as the industry<br />
leader we believe our triennial revalidation program is an important service to our customers in<br />
assuring continuity of compliance.<br />
TECHNICAL AND MATERIAL SAFETY DATA SHEETS:<br />
USA<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, call:<br />
1.800.323.5106<br />
For your nearest authorized <strong>Loctite</strong> ® brand<br />
distributor, to arrange an in-plant seminar or<br />
for technical product assistance, call:<br />
1.800.LOCTITE (1.800.562.8483)<br />
To place an order, call:<br />
1.800.243.4874<br />
Henkel Corporation<br />
1001 Trout Brook Crossing<br />
Rocky Hill, Connecticut 06067<br />
860.571.5100<br />
Fax: 860.571.5465<br />
Canada<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, for your nearest authorized<br />
<strong>Loctite</strong> ® brand distributor, to arrange an<br />
in-plant seminar, for technical product assistance<br />
or to place an order, call:<br />
1.800.263.5043 (within Canada)<br />
Henkel Canada Corporation<br />
2225 Meadowpine Blvd.<br />
Mississauga, Ontario L5N 7P2<br />
Tel: 905.814.6511<br />
Fax: 905.814.5391<br />
1.800.263.5043 (within Canada)<br />
Mexico<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, for your nearest authorized<br />
<strong>Loctite</strong> ® brand distributor, to arrange an<br />
in-plant seminar or for technical product<br />
assistance, call:<br />
01.800.90.181.00 (within Mexico)<br />
To place an order, call:<br />
01.800.84.994.12 (within Mexico)<br />
Henkel Capital, S.A. de C.V.<br />
Calzada de la Viga s/n Fracc. Los Laureles<br />
Loc. Tulpetlac, C.P. 55090<br />
Ecatepec de Morelos, Edo. de México<br />
Tel: 011.52.55.5836.1300<br />
Fax: 011.52.55.5787.9004<br />
Central America<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, for your nearest authorized<br />
<strong>Loctite</strong> ® brand distributor, to arrange an<br />
in-plant seminar, for technical product assistance<br />
or to place an order, call:<br />
506.277.4868<br />
Henkel Costa Rica Ltda.<br />
San Joaquin de Flores<br />
Heredía, Costa Rica<br />
Tel: 506.277.4800<br />
Fax: 506.277.4883<br />
South America<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, for your nearest authorized<br />
<strong>Loctite</strong> ® brand distributor, to arrange an in-plant<br />
seminar, for technical product assistance or to<br />
place an order, contact:<br />
Henkel Ltda.<br />
Rua Karl Huller, 136 – Jd.<br />
Canhema 09941-410<br />
Diadema/SP, Brazil<br />
Tel: 55.11.4075.8955<br />
Fax: 55.11.4075.8887<br />
0800.12.23.34 (within Brazil)<br />
Henkel Argentina S.A.<br />
Tte. Cnel. Magán 1990 – Sarandi<br />
(B1872HRN) Avellanda, Buenos Aires, Argentina<br />
Tel: 54.11.4001.0100<br />
Fax: 54.11.4205.3442<br />
0800.33.30213 (within Argentina)<br />
Henkel Chile Ltda.<br />
Av. Apoquindo 3355,<br />
Oficina 8 – 1º Piso<br />
Las Condes, Santiago, Chile<br />
Tel: 56.2.2333606<br />
Fax: 56.2.2341448<br />
800.212002 (within Chile)<br />
Henkel Colombiana S.A.<br />
Calle 17 No. 68-B-73,<br />
Bogotá D.C., Colombia<br />
Tel: 571.423.9000<br />
Fax: 571.425.1331<br />
01.800.01.14173 (within Colombia)<br />
INSTANT access to comprehensive technical and material safety data sheets is available on the<br />
<strong>Loctite</strong> ® website. Most are available in various languages. Technical data sheets are integrated<br />
with our material specifications and all products are tested on a batch to batch basis. Locate any<br />
<strong>Loctite</strong> ® technical data sheet using a product or item number, and safety data sheets using an<br />
item number.<br />
Henkel Venezolana S.A.<br />
Zona Industrial Pruinca<br />
Calle 2 Parcela 31 y 32<br />
Guacara – Edo Carabobo, Venezuela<br />
Tel: 5824.5560.2611<br />
Fax: 5824.5560.2660<br />
0800.436.5300 (within Venezuela)<br />
Henkel Corporation<br />
Engineering, Assembly & Maintenance Technologies<br />
1001 Trout Brook Crossing • Rocky Hill, CT 06067 U.S.A. • 800-562-8483 • www.henkel.us • www.loctite.com<br />
All trademarks listed in this selector guide are trademarks of Henkel Corporation, U.S.A.<br />
© Copyright 2004. Henkel Corporation. All rights reserved. 2196/LT-864H 11/04
USA<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, call:<br />
1.800.323.5106<br />
For your nearest authorized <strong>Loctite</strong> ® brand<br />
distributor, to arrange an in-plant seminar or<br />
for technical product assistance, call:<br />
1.800.LOCTITE (1.800.562.8483)<br />
To place an order, call:<br />
1.800.243.4874<br />
Henkel Corporation<br />
1001 Trout Brook Crossing<br />
Rocky Hill, Connecticut 06067<br />
860.571.5100<br />
Fax: 860.571.5465<br />
Canada<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, for your nearest authorized<br />
<strong>Loctite</strong> ® brand distributor, to arrange an<br />
in-plant seminar, for technical product assistance<br />
or to place an order, call:<br />
1.800.263.5043 (within Canada)<br />
Henkel Canada Corporation<br />
2225 Meadowpine Blvd.<br />
Mississauga, Ontario L5N 7P2<br />
Tel: 905.814.6511<br />
Fax: 905.814.5391<br />
1.800.263.5043 (within Canada)<br />
Mexico<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, for your nearest authorized<br />
<strong>Loctite</strong> ® brand distributor, to arrange an<br />
in-plant seminar or for technical product<br />
assistance, call:<br />
01.800.90.181.00 (within Mexico)<br />
To place an order, call:<br />
01.800.84.994.12 (within Mexico)<br />
Henkel Capital, S.A. de C.V.<br />
Calzada de la Viga s/n Fracc. Los Laureles<br />
Loc. Tulpetlac, C.P. 55090<br />
Ecatepec de Morelos, Edo. de México<br />
Tel: 011.52.55.5836.1300<br />
Fax: 011.52.55.5787.9004<br />
Central America<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, for your nearest authorized<br />
<strong>Loctite</strong> ® brand distributor, to arrange an<br />
in-plant seminar, for technical product assistance<br />
or to place an order, call:<br />
506.277.4868<br />
Henkel Costa Rica Ltda.<br />
San Joaquin de Flores<br />
Heredía, Costa Rica<br />
Tel: 506.277.4800<br />
Fax: 506.277.4883<br />
South America<br />
For your local <strong>Loctite</strong> ® brand Adhesives and<br />
Sealants Specialist, for your nearest authorized<br />
<strong>Loctite</strong> ® brand distributor, to arrange an in-plant<br />
seminar, for technical product assistance or to<br />
place an order, contact:<br />
Henkel Ltda.<br />
Rua Karl Huller, 136 – Jd.<br />
Canhema 09941-410<br />
Diadema/SP, Brazil<br />
Tel: 55.11.4075.8955<br />
Fax: 55.11.4075.8887<br />
0800.12.23.34 (within Brazil)<br />
Henkel Argentina S.A.<br />
Tte. Cnel. Magán 1990 – Sarandi<br />
(B1872HRN) Avellanda, Buenos Aires, Argentina<br />
Tel: 54.11.4001.0100<br />
Fax: 54.11.4205.3442<br />
0800.33.30213 (within Argentina)<br />
Henkel Chile Ltda.<br />
Av. Apoquindo 3355,<br />
Oficina 8 – 1º Piso<br />
Las Condes, Santiago, Chile<br />
Tel: 56.2.2333606<br />
Fax: 56.2.2341448<br />
800.212002 (within Chile)<br />
Henkel Colombiana S.A.<br />
Calle 17 No. 68-B-73,<br />
Bogotá D.C., Colombia<br />
Tel: 571.423.9000<br />
Fax: 571.425.1331<br />
01.800.01.14173 (within Colombia)<br />
Henkel Venezolana S.A.<br />
Zona Industrial Pruinca<br />
Calle 2 Parcela 31 y 32<br />
Guacara – Edo Carabobo, Venezuela<br />
Tel: 5824.5560.2611<br />
Fax: 5824.5560.2660<br />
0800.436.5300 (within Venezuela)<br />
Henkel Corporation<br />
Engineering, Assembly & Maintenance Technologies<br />
1001 Trout Brook Crossing • Rocky Hill, CT 06067 U.S.A. • 800-562-8483 • www.henkel.us • www.loctite.com<br />
All trademarks in this brochure, except where noted, are trademarks of Henkel Corporation, U.S.A. K-Resin is a reistered<br />
trademark of Chevron Phillips Chemical, Snap Swab is a reistered trademark of Medical Packaging Corporation, Dacron<br />
is a reistered trademark of DAK America. © Copyright 2004. Henkel Corporation. All rights reserved. 2196/LT-2399 6/04