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Annual Congress of <strong>Malaysian</strong> <strong>Thoracic</strong> <strong>Society</strong><br />

PP 21<br />

Role of PET/CT in the management of Lung Cancer<br />

A M Razak 1 , V Shanty 2 , S M Leong 3 , H Fadzilah 4<br />

1<br />

Institut Perubatan Respiratory, Kuala Lumpur, Malaysia<br />

2<br />

Oncology Department, Hospital Pulau Pinang, Penang, Malaysia<br />

3<br />

Oncology Department, University Malaya Medical Centre, Kuala Lumpur, Malaysia<br />

4<br />

Nuclear Medicine Department, Hospital Pulau Pinang, Penang, Malaysia<br />

Abstract<br />

Positron emission tomography (PET) is a unique imaging technique that provides details of functional processes<br />

in the body. Through the integration of CT and PET, form and function are merged to create a better imaging<br />

tool, particularly in the staging and diagnosis of lung cancer. This is a retrospective evaluation of the use of<br />

this PET/CT scanning for lung cancer at Penang Hospital, done for the year 2008 to 2010.<br />

Method<br />

All patients referred from the Respiratory Department, Penang Hospital to the Nuclear Medicine Department,<br />

Penang Hospital for the 3 years were evaluated by the physicians from both these departments.<br />

Results<br />

A total of 74 cases were evaluated. The racial distributions were Chinese 44, Malay 18, Indian 8 and others 4.<br />

More than half, (53%), were 60 years of age and above. Patients referred for staging were, 21, re-staging 19,<br />

treatment response 16, diagnosis 9 and recurrence 9. For those referred for staging, 57% were upgraded and<br />

29% were downgraded. About 33% were diagnosed as malignant, for cases sent for diagnostic evaluation,<br />

and these were confirmed by biopsy.<br />

Conclusion<br />

PET/CT is the preferred noninvasive method for staging lung cancer. PET/CT is more accurate in detecting<br />

lymph node metastases compared with CT alone. By fusing the two datasets together, PET/CT provides an<br />

improved method to accurately evaluate for local and distant metastatic disease. In this study, 57% of the<br />

cases were upgraded, thus altering the line of management and its use in diagnosing lung nodules is proven<br />

by a positive tissue diagnosis post PET/CT in 33% of cases. Furthermore, a number of distant metastases were<br />

detected, which alters the plan for management, especially surgical intervention.<br />

83

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