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Annual Congress of <strong>Malaysian</strong> <strong>Thoracic</strong> <strong>Society</strong><br />
PP 21<br />
Role of PET/CT in the management of Lung Cancer<br />
A M Razak 1 , V Shanty 2 , S M Leong 3 , H Fadzilah 4<br />
1<br />
Institut Perubatan Respiratory, Kuala Lumpur, Malaysia<br />
2<br />
Oncology Department, Hospital Pulau Pinang, Penang, Malaysia<br />
3<br />
Oncology Department, University Malaya Medical Centre, Kuala Lumpur, Malaysia<br />
4<br />
Nuclear Medicine Department, Hospital Pulau Pinang, Penang, Malaysia<br />
Abstract<br />
Positron emission tomography (PET) is a unique imaging technique that provides details of functional processes<br />
in the body. Through the integration of CT and PET, form and function are merged to create a better imaging<br />
tool, particularly in the staging and diagnosis of lung cancer. This is a retrospective evaluation of the use of<br />
this PET/CT scanning for lung cancer at Penang Hospital, done for the year 2008 to 2010.<br />
Method<br />
All patients referred from the Respiratory Department, Penang Hospital to the Nuclear Medicine Department,<br />
Penang Hospital for the 3 years were evaluated by the physicians from both these departments.<br />
Results<br />
A total of 74 cases were evaluated. The racial distributions were Chinese 44, Malay 18, Indian 8 and others 4.<br />
More than half, (53%), were 60 years of age and above. Patients referred for staging were, 21, re-staging 19,<br />
treatment response 16, diagnosis 9 and recurrence 9. For those referred for staging, 57% were upgraded and<br />
29% were downgraded. About 33% were diagnosed as malignant, for cases sent for diagnostic evaluation,<br />
and these were confirmed by biopsy.<br />
Conclusion<br />
PET/CT is the preferred noninvasive method for staging lung cancer. PET/CT is more accurate in detecting<br />
lymph node metastases compared with CT alone. By fusing the two datasets together, PET/CT provides an<br />
improved method to accurately evaluate for local and distant metastatic disease. In this study, 57% of the<br />
cases were upgraded, thus altering the line of management and its use in diagnosing lung nodules is proven<br />
by a positive tissue diagnosis post PET/CT in 33% of cases. Furthermore, a number of distant metastases were<br />
detected, which alters the plan for management, especially surgical intervention.<br />
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