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Annual Congress of Malaysian Thoracic Society
PP 8
Pathogen and Sensitivity Pattern in a Hospital
Treating Pulmonary Diseases
Nurhayati M M, Izayu N, Liza A F, Muventhiran, Jasminder K, Dora A A,
Aziah A M, Abdul Razak M
Institut Perubatan Respiratori, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
Background
Most guidelines on community acquired pneumonia still name Streptococcus pneumoniae as the main
pathogen, but as a centre treating respiratory diseases, organisms isolated would be mostly gram-negative
as we are dealing with damaged and diseased lungs. It is also alarming that the resistance of these gramnegative
organisms to wide spectrum antibiotics is increasing.
Method
A surveillance study was carried out from 1 January 2009 until 31 December 2010. All sputum, tracheal
aspirate, bronchial washing and pleural fluid specimens that were sent for cultures from outpatient and
inpatient department, were included in the study. The specimens were investigated according to standard
microbiological test and subjected to antibiotic susceptibility testing.
Results
Throughout the period, there were 1716 positive cultures. Klebsiella species was the most common pathogen,
627 (36.54%); followed by Haemophilus parainfluenza 296 (17.25%) and Pseudomonas aeruginosa 208 (12.12%).
Only 33 (1.92%) cultures grew Streptococcus pneumonia. In 5.71% of the cultures, extended spectrum
beta-lactamase was detected. Methicillin-resistant Staphylococcus aureus accounted for 20.37% of the
Staphylococcus aureus growth.
Conclusion
Gram-negative organisms are the most common organism in hospitals dealing with respiratory diseases and
there is an increasing percentage of resistant organisms.
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