download - Malaysian Thoracic Society
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Annual Congress of <strong>Malaysian</strong> <strong>Thoracic</strong> <strong>Society</strong><br />
OP 3<br />
Survival of Lung Cancer in Alor Setar Kedah:<br />
A Retrospective Cohort Study 2004-2010<br />
Razul Kassim 1 , Mustafa Kamal 1 , Aniza A A 2<br />
1<br />
Department of Respiratory Medicine , Hospital Sultanah Bahiyah, Alor Setar, Kedah, Malaysia<br />
2<br />
Unit of Biostatistics & Research Methodology, School of Medical Sciences, Universiti Sains Malaysia,<br />
Kubang Kerian, Kelantan, Malaysia<br />
Objective<br />
The aim of the study was to evaluate the survival of lung cancer patients in Alor Setar, Kedah from year 2004<br />
to 2010.<br />
Materials & Methods<br />
A retrospective cohort study was conducted involving 103 lung cancer patients treated in Hospital Sultanah<br />
Bahiyah, Alor Setar, Kedah from January 2004 until December 2010. Patients’ information was obtained<br />
from their medical records and telephone calls. Kaplan Meier product-limit (PL) estimates was applied and<br />
expressed as percentages with 95% confidence intervals. The comparison of survival distributions in variable<br />
groups were evaluated using the Log-rank test.<br />
Results<br />
The overall cumulative survival for lung cancer in Kedah was 83.5 (95% confidence interval (CI): 81.5, 85.5),<br />
73.8 (95% CI: 65.4, 82.2), 62.1 (95% CI: 52.6, 71.5) and 33.0 (95% CI: 32.9, 51.2) percent for 1 month, 3 months,<br />
6 months and 1 year respectively. There were significant higher one year survival probabilities of those<br />
receiving first line (Yes, 38% vs No, 15%), receiving second line (Yes, 65% vs No, 28%), greater frequency of<br />
chemotherapy cycle (6 cycle, 48 % vs stop chemotherapy, 10%), better score before chemotherapy (1, 45%<br />
vs 3, 8%), lower than stage 4 (non stage 4, 56 % vs Stage 4, 20%), complete 3 months remission (complete<br />
remission, 35% vs stop chemotherapy, 18%) and complete 6 months remission (complete remission, 58% vs<br />
no chemotherapy, 15 %).<br />
Conclusion<br />
The survival of lung cancer patients treated in Alor Setar was comparable with other developed countries.<br />
Keyword<br />
Survival, cumulative survival, lung cancer<br />
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