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Annual Congress of <strong>Malaysian</strong> <strong>Thoracic</strong> <strong>Society</strong><br />

OP 3<br />

Survival of Lung Cancer in Alor Setar Kedah:<br />

A Retrospective Cohort Study 2004-2010<br />

Razul Kassim 1 , Mustafa Kamal 1 , Aniza A A 2<br />

1<br />

Department of Respiratory Medicine , Hospital Sultanah Bahiyah, Alor Setar, Kedah, Malaysia<br />

2<br />

Unit of Biostatistics & Research Methodology, School of Medical Sciences, Universiti Sains Malaysia,<br />

Kubang Kerian, Kelantan, Malaysia<br />

Objective<br />

The aim of the study was to evaluate the survival of lung cancer patients in Alor Setar, Kedah from year 2004<br />

to 2010.<br />

Materials & Methods<br />

A retrospective cohort study was conducted involving 103 lung cancer patients treated in Hospital Sultanah<br />

Bahiyah, Alor Setar, Kedah from January 2004 until December 2010. Patients’ information was obtained<br />

from their medical records and telephone calls. Kaplan Meier product-limit (PL) estimates was applied and<br />

expressed as percentages with 95% confidence intervals. The comparison of survival distributions in variable<br />

groups were evaluated using the Log-rank test.<br />

Results<br />

The overall cumulative survival for lung cancer in Kedah was 83.5 (95% confidence interval (CI): 81.5, 85.5),<br />

73.8 (95% CI: 65.4, 82.2), 62.1 (95% CI: 52.6, 71.5) and 33.0 (95% CI: 32.9, 51.2) percent for 1 month, 3 months,<br />

6 months and 1 year respectively. There were significant higher one year survival probabilities of those<br />

receiving first line (Yes, 38% vs No, 15%), receiving second line (Yes, 65% vs No, 28%), greater frequency of<br />

chemotherapy cycle (6 cycle, 48 % vs stop chemotherapy, 10%), better score before chemotherapy (1, 45%<br />

vs 3, 8%), lower than stage 4 (non stage 4, 56 % vs Stage 4, 20%), complete 3 months remission (complete<br />

remission, 35% vs stop chemotherapy, 18%) and complete 6 months remission (complete remission, 58% vs<br />

no chemotherapy, 15 %).<br />

Conclusion<br />

The survival of lung cancer patients treated in Alor Setar was comparable with other developed countries.<br />

Keyword<br />

Survival, cumulative survival, lung cancer<br />

50

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