Immunology & Inflammation

w w w . i m g e n e x . c o m 

Immunology & Inflammation 

R E S E A R C H T O O L S 

Tools, Ligands, Antibodies 

and Reagents for Innate & 

Adaptive Immunity 

TLRs & Associated Proteins 

TLR Agonists 

T Cells 

Inflammation 

NF-κB Pathways 

Stable Cell Lines 

Screening Services 

for Inflammation 

& Immune Signaling 

Pathways 

w w w . i m g e n e x . c o m

IMGENEX TLRSystem - Tools, Ligands, Antibodies and 

Reagents: A Complete System portfolio for in depth 

understanding and analysis of cell networks, signaling 

pathway molecules, markers and mediators all of which 

comprise Innate and Adaptive Immune Responses. 

The IMGENEX TLRSystem portfolio includes antibodies, kits and reagents to 

study Toll-like Receptors (TLRs), MyD88 and other TLR adapter molecules, Peptide 

Inhibitors (MyD88, NF-kB and TLR), Pro-Inflammatory Cytokines and CD 

Markers. The IMGENEX TLRSystem is an enabling portfolio for in depth understanding 

and analysis of cell networks, signaling pathway molecules, markers 

and mediators all of which comprise Innate and Adaptive Immune Responses. 

TLRSystem products are optimized for applications and platforms including 

Flow Cytometry, Functional Assays, Immunohistochemistry or Western Blotting 

technologies. Featured products include: 

• Fluorochrome conjugates for TLRs & CD Phenotyping 

• Markers for Dendritic Cells (DCs), Antigen-Presenting Cells (APCs) 

• T Cell and T Cell subset phenotyping markers 

• NF-kB SEAPorter Assay Kits, Cell lines & Reagents for fast, 

flexible screening of NF-kB Activation 

• Peptide Inhibitors of NF-kB Signaling Pathway molecules 

• ActivELISA Kits for Cytokines, Chemokines & Pro-Inflammatory 

Mediators- IkBa, IL-1b, NF-kB, PGE 2 

, TNFa 

• Cell and Tissue Lysates, and ready-to-use INSTA-Blots for 

Western Blots or proteomic analysis 

Application Key FA-A - Functional Assay (Activation) FA-Neut - Functional Assay (Neutralization) Flow-CS+Intra - Flow (Cell Surface) and Flow (Intracellular) 

IF/ICC - Immunofluorescence/Immunocytochemistry CM - Confocal Microscopy Flow-CS - Flow (Cell Surface) Flow-Intra - Flow (Intracellular) 

IHC-Fr - Immunohistochemistry (Frozen) IP - Immunoprecipitation IHC-P - Immunohistochemistry (Paraffin) WB - Western Blot PAP Peptide Affinity Purified 

TLRSystem TM 1

P 

S 

4 

F6 

TRIF 

TLR4 

MD-2 

TRAM 

TLR4 

MyD88 

LPS 

TIRAP 

Bacteria 

BTK 

Viral 

dsRNA 

PΙ3K 

RIP2 

RAC TLR1 

TLR2 

TLR2 

TLR2 

MyD88 

TIRAP 

Yeast 

Zymosan 

PΙ3K 

IRAK4 

IRAK1 

RIP2 

RAC 

MyD88 

TIRAP 

TAB1 

TAB2 

TAK1 

CD14 

PΙ3K 

LAM 

LTA 

Bacteria BLP 

PGN 

TLR2 

TLR6 

RIP2 

RAC 

MyD88 

TIRAP 

Viral 

Bacteria 

TLR10 

RIP1 

TRIF 

TLR3 

TRAF6 

MKK6 

MKK3 

IκB 

p50 p65 

IKKα IKKβ 

IKKγ 

JNK 

K1 

IKKα 

IKKγ 

IKKβ 

TBK1 

IKKε 

IκB 

p50 p65 

TANK 

IRF3 

p38 

IFN-β 

IRF3 

p50 p65 

CREB 

TNF, COX2, 

IL-18 

Slam, CD80, CD83 

ATF2 

c-Jun 

IFN-α 

IRF 

IFN 

Res 

Gen 

2 

T 8 8 8 - 7 2 3 - 4 3 6 3 F 8 5 8 - 6 4 2 - 0 9 3 7 E i n f o @ i m g e n e x . c o m

Table of Contents 

Antibodies. . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 

TLR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 

TLR Ligands. . . . . . . . . . . . . . . . . . . . . . . .7 

TLR Related Proteins . . . . . . . . . . . . . . . . . 8 

Infl ammation . . . . . . . . . . . . . . . . . . . . . . . 11 

CD Markers. . . . . . . . . . . . . . . . . . . . . . . . 12 

and 

l CpG 

Flagellin 

Uropathogenic 

Bacteria 

Regulatory T Cells . . . . . . . . . . . . . . . . . . 17 

NF-kB . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 

Cytokines & Chemokines . . . . . . . . . . . . . 24 

MALP-2 

TLR5 

TLR11 

TLR12 

TLR13 

ActivELISA and ActivAssay Kits. . . . . . . . . 27 

NF-kB Pathway 

Inhibitory Peptides . . . . . . . . . . . . . . . . . . . . 28 

CD36 

MyD88 

Stable Cell Lines. . . . . . . . . . . . . . . . . . . . . . 29 

? 

MyD88 

Screening Services . . . . . . . . . . . . . . . . . . . 30 

8 

MyD88 

BTK 

TLR7/8/9 

- 

ponsible 

e 

IRF7 

MyD88 

TRAF6 

IRF7 




TLRSystem TM 3

antibodies 

Toll-like Receptors 

Description Cat No Format Clone Host Species Application 

TLR1/CD281 IMG-5012 Purified N/A Rabbit H, M, R Flow-CS+Intra, WB 

TLR3/CD283 

(IMG-315A) 

IHC analysis of TLR3 in (A) 

human gut lumen (longitudinal 

section, transverse 

region) using IMG-315A at 

10 ug/ml (Data courtesy Dr. 

Elizabeth Furrie, University 

of Dundee) and mouse 

spleen tissue using isotype 

control (B) and IMG-315A 

(C) at 5 mg/ml. 

NEW 

NEW 

IMG-5012AF488 Alexa Fluor® 488 N/A Rabbit H, M, R Flow-CS+Intra 


TLR1/CD281 IMG-5629 Purified N/A Rabbit H, M WB 

TLR2/CD282 IMG-319 Ascites 1030A5.138 Mouse H Flow-CS+Intra, IHC-P, WB 

TLR2/CD282 IMG-410A Purified N/A Rabbit H, M IHC-P, WB 

IMG-410E Azide-Free N/A Rabbit H, M WB 

TLR2/CD282 IMG-416A Purified TL2.1 Mouse Dog, H Flow-CS+Intra, IF/ICC, IHC-P, 

IP, WB 

IMG-416B Biotin TL2.1 Mouse Dog, H Flow-CS+Intra, IF/ICC, IP 

IMG-416AF488 Alexa Fluor® 488 TL2.1 Mouse Dog, H Flow-CS+Intra, IF/ICC 

IMG-416AF647 Alexa Fluor® 647 TL2.1 Mouse Dog, H Flow-CS+Intra, IF/ICC 

IMG-416C FITC TL2.1 Mouse Dog, H Flow-CS+Intra, IF/ICC 

IMG-416D PE TL2.1 Mouse Dog, H Flow-CS+Intra, IF/ICC 

IMG-416E Azide-Free TL2.1 Mouse Dog, H FA-Neut, Flow-CS+Intra, IF/ICC, 

IP 

TLR2/CD282 IMG-526 Purified N/A Rabbit H, M WB 

TLR2/CD282 IMG-545 Purified Rabbit Chimp, H, M, R WB 

TLR2/CD282 IMG-5651 Purified N/A Rabbit H, M IHC-P, WB 

TLR2/CD282 IMG-6320A Purified T2.5 Mouse H, M FA-Neut, Flow-CS, IHC-Fr, IP 

IMG-6320C FITC T2.5 Mouse H, M FA-Neut, Flow-CS, IHC-Fr, IP 

TLR2/CD282 IMG-662 Purified N/A Rabbit M WB 

TLR2/CD282 IMG-545E Azide-Free N/A Rabbit Multi-species WB 

TLR3/CD283 IMG-315A Purified 40C1285.6 Mouse Dog, H Flow-CS+Intra, IF/ICC, IHC-P, 

IP, WB 

IMG-315AF488 Alexa Fluor® 488 40C1285.6 Mouse Dog, H, M Flow-CS+Intra, IF/ICC 


IMG-315B Biotin 40C1285.6 Mouse Dog, H, M ELISA 

IMG-315C FITC 40C1285.6 Mouse Dog, H, M Flow-CS+Intra, IF/ICC 

IMG-315D PE 40C1285.6 Mouse Dog, H, M Flow-CS+Intra, IF/ICC 

TLR3/CD283 IMG-516 Purified N/A Rabbit M Flow-CS+Intra, IHC-Fr, IHC-P, WB 

IMG-516C FITC N/A Rabbit M Flow-CS+Intra 

TLR3/CD283 (CT) IMG-5631-1 Purified N/A Rabbit H, M WB 

TLR3/CD283 (Tyr759) IMG-5348A PAP N/A Rabbit H IF/ICC, IHC-Fr, WB 

TLR3/CD283 IMG-6315A PAP N/A Rabbit Multi-species IHC-P, WB 

TLR4/CD284 IMG-6285A PAP N/A Rabbit Multi-species WB 

TLR4/CD284 IMG-6307A PAP N/A Rabbit Multi-species WB 

TLR4/CD284 IMG-417A Purified HTA125 Mouse Dog, H CM, FA-Neut, Flow-CS+Intra, 

IF/ICC, IP 

IMG-417AF647 Alexa Fluor® 647 HTA125 Mouse Dog, H CM, Flow-CS, Flow-Intra 

IMG-417B Biotin HTA125 Mouse Dog, H CM, ELISA, FA-Neut, 

Flow-CS+Intra, IF/ICC, IP 

IMG-417C FITC HTA125 Mouse Dog, H Flow-CS+Intra 

IMG-417D PE HTA125 Mouse Dog, H CM, Flow-CS+Intra 

IMG-417E Azide-Free HTA125 Mouse Dog, H CM, FA-Neut, Flow-CS+Intra, 

IF/ICC, IP 

4 



TLR4/CD284 IMG-428A Purified MTS510 Rat M Flow-CS, IP 

NEW 

IMG-428AF647 Alexa Fluor® 647 MTS510 Rat M Flow-CS 

IMG-428C FITC MTS510 Rat M Flow-CS 

IMG-428D PE MTS510 Rat M Flow-CS 

IMG-428E Azide-Free MTS510 Rat M FA-Neut, Flow-CS, IP 

TLR4/CD284 IMG-5031A Purified 76B357.1 Mouse H, M, R Flow-CS+Intra, IHC-P, WB 

IMG-5031AF647 Alexa Fluor® 647 76B357.1 Mouse H, M, R Flow-CS+Intra 

IMG-5031C FITC 76B357.1 Mouse H, M, R Flow-CS+Intra 

IMG-5031D PE 76B357.1 Mouse H, M, R Flow-CS+Intra 

TLR4/CD284 IMG-577 Purified N/A Rabbit H, M IP, WB 

TLR4/CD284 IMG-578A Purified N/A Rabbit H, M WB 

TLR4/CD284 IMG-579A Purified N/A Rabbit H, M Flow-CS, IHC-Fr, IHC-P, WB 

TLR4/CD284 (Tyr674) IMG-6276A PAP N/A Rabbit H, M, R WB 

TLR5 IMG-580 Purified N/A Rabbit H, M, R Flow-Intra, IHC-P, WB 

TLR5 IMG-663A Purified 85B152.5 Mouse Dog, H, M Flow-CS+Intra, WB 

IMG-663C FITC 85B152.5 Mouse Dog, H, M Flow-CS+Intra 

IMG-663D PE 85B152.5 Mouse Dog, H, M Flow-CS+Intra 

TLR5 IMG-664A Purified 19D759.2 Mouse Dog, H, M Flow-CS+Intra, IHC-Fr, IHC-P, WB 

IMG-664AF488 Alexa Fluor® 488 19D759.2 Mouse Dog, H, M Flow-CS+Intra 

IMG-664AF647 Alexa Fluor® 647 19D759.2 Mouse Dog, H, M Flow-CS+Intra 

IMG-664C FITC 19D759.2 Mouse Dog, H, M Flow-CS+Intra 

IMG-664D PE 19D759.2 Mouse Dog, H, M Flow-CS+Intra 

TLR5 IMX-5131 Sera N/A Rabbit H ELISA 

TLR6/CD286 IMG-304A Purified 86B1153.2 Mouse H Flow-CS, IHC-P 

IMG-304AF488 Alexa Fluor® 488 86B1153.2 Mouse H Flow-CS+Intra 


IMG-304B Biotin 86B1153.2 Mouse H ELISA 

IMG-304C FITC 86B1153.2 Mouse H Flow-CS+Intra 

IMG-304D PE 86B1153.2 Mouse H Flow-CS+Intra 

TLR6/CD286 IMG-5239 Sera N/A Rabbit H IHC-P 

TLR6/CD286 IMG-527 Purified N/A Rabbit H, M Flow-Intra, WB 

TLR6/CD286 IMX-5260 Sera N/A Rabbit H ELISA 

TLR7 IMG-540 Purified N/A Rabbit H, M WB 

TLR7 IMG-5632 Purified N/A Rabbit H, M WB 

TLR7 IMG-581A Purified N/A Rabbit H, M Flow-CS, IF/ICC, IHC-Fr, IHC-P, 

IP, WB 

IMG-581C FITC N/A Rabbit H, M Flow-CS+Intra 

IMG-581E Azide-Free N/A Rabbit H, M Flow-CS, IF/ICC, IHC-Fr, IHC-P, 

IP, WB 

TLR7 IMG-6070A Purified N/A Rabbit Multi-species Flow-Intra, WB 

TLR7 IMG-665A Purified N/A Rabbit H, M Flow-CS+Intra, IHC-Fr, WB 

IMG-665C FITC N/A Rabbit H, M Flow-CS+Intra 

IMG-665D PE N/A Rabbit H, M Flow-CS+Intra 

Toll-like Receptors antibodies 




TLRSystem TM 5

antibodies 

Toll-like Receptors 


TLR9/CD289 

(IMG-305A) 

IHC analysis of TLR9 in 

Adenocarcinoma of the 

lung (A), A549 cells (C), 

and malignant lung tissues 

(F) at 1:100 dilution, (600 × 

magnification). 

TLR8/CD288 IMG-321A Purified 44C143 Mouse H, M Flow-CS+Intra, IHC-P, WB 

IMG-321AF488 Alexa Fluor® 488 44C143 Mouse H, M Flow-CS+Intra 


IMG-321B Biotin 44C143 Mouse H, M ELISA 

IMG-321C FITC 44C143 Mouse H, M Flow-CS+Intra 

IMG-321D PE 44C143 Mouse H, M Flow-CS+Intra 

TLR8/CD288 IMG-5653-1 Purified N/A Rabbit H, M IF/ICC, WB 

TLR9/CD289 IMG-305A Purified 26C593.2 Mouse Multi-species CM, Flow-CS+Intra, IF/ICC, 

IHC-Fr, IHC-P, WB 

IMG-305AF488 Alexa Fluor® 488 26C593.2 Mouse Multi-species CM, Flow-CS+Intra, IF/ICC 


IMG-305B Biotin 26C593.2 Mouse Multi-species ELISA 

IMG-305C FITC 26C593.2 Mouse Multi-species CM, Flow-CS+Intra, IF/ICC, 


IMG-305D PE 26C593.2 Mouse Multi-species CM, Flow-CS+Intra, IHC-Fr, 

IHC-P 

IMG-305E Azide-Free 26C593.2 Mouse Multi-species CM, Flow-CS+Intra, IF/ICC, 


TLR9/CD289 IMG-431 Purified N/A Rabbit H, M Flow-CS+Intra, IF/ICC, IHC-Fr, 

IHC-P, WB 

TLR10/CD290 IMG-386A Purified 158C1114 Mouse H Flow-CS+Intra, WB 

IMG-386C FITC 158C1114 Mouse H Flow-CS+Intra 

IMG-386D PE 158C1114 Mouse H Flow-CS+Intra 

TLR10/CD290 IMG-5255A Purified N/A Rabbit M, R ELISA, WB 

TLR10/CD290 (IN) IMG-5630 Purified N/A Rabbit H WB 

TLR11 IMG-5104A Purified N/A Rabbit M, R Flow-Intra, WB 

IMG-5104C FITC N/A Rabbit M, R Flow-Intra 

TLR11 (IN) IMG-5650 Purified N/A Rabbit M IF/ICC, WB 

TLR12 IMG-5034 Purified N/A Rabbit M Flow-Intra, WB 

IMG-5034C FITC N/A Rabbit M Flow-Intra 

TLR12 IMG-5037 Ascites 15F1215 Mouse M WB 

TLR13 IMX-5167 Sera N/A Rabbit M, R ELISA 




6 


Toll-like Receptor Agonists! 

Toll-like Receptors antibodies 

Stimulate Your Research with IMGENEX 

Toll-like Receptor (TLR) agonists are key research tools for elucidating downstream 

signaling events associated with pathogen identification and subsequent immunomodulatory 

activity. IMGENEX offers a growing suite of Toll-like Receptor ligands to 

complement its portfolio of validated antibodies, peptide inhibitors, and tissue lysates. 

Pair with one of our peptide inhibitors, or NF-kB p65 ActivELISA Assay to measure 

activation! 

Toll-like Receptor Ligands 

Description Cat No Quantity 

Pam3CSK4, TLR1 and TLR2 Ligand IMG-2201 0.025 mg 

Poly(I).Poly(C), TLR3 Ligand IMG-2203 1.0 mg 

LPS from E. Coli, TLR4 Ligand IMG-2204 0.05 mg 

Flagellin, Recombinant, TLR5 Ligand IMG-2205 0.01 mg 

MALP-2, TLR6/TLR2 Ligand IMG-2206 2.0 µg 

Imiquimod, TLR7 Ligand IMG-2207 125 µg 

Imidazoquinoline Resiquimod (R-848), TLR8 Ligand IMG-2208 500 µg 

CpG ODN (1668) with negative control oligo, TLR9 Ligand mouse IMG-2209M 0.1 mg 

CpG ODN (2006) with negative control oligo, TLR9 Ligand human IMG-2209H 0.1 mg 




TLRSystem TM 7

antibodies 

Toll-like Receptors Related Proteins 


NOD2 

(IMG-5738) 

A 

Formalin-fixed, paraffinembedded 

normal human 

colon stained for NOD2 

expression using IMG-5738 

at 1:2000. A, tissue core 

from a colon tissue microarray. 

A1, high magnification 

of A. Hematoxylineosin 

counterstain. 

A20 IMG-161A Purified 59A426 Mouse H IP, WB 

ABIN-2 IMG-434 Purified N/A Rabbit H, M, R WB 

ACAP2 IMG-6355A PAP N/A Rabbit Multi-species WB 

ACT IMG-4043 Purified N/A Rabbit H WB 

ARAP1 IMX-6347 Sera N/A Rabbit Multi-species ELISA 

BMI1 IMX-6345 Sera N/A Rabbit Multi-species ELISA 

BTK (NT) IMG-5431 PAP N/A Rabbit H, M WB 

CD11b IMG-6292C FITC 5C6 Rat M Flow-CS 

IMG-6292D PE 5C6 Rat M Flow-CS 

IMG-6292G APC 5C6 Rat M Flow-CS 

CD14 IMG-3991 PAP N/A Goat H WB 

CD19 IMG-6294A Purified 1D3 Rat M Flow-CS 

IMG-6294C FITC 1D3 Rat M Flow-CS 

IMG-6294D PE 1D3 Rat M Flow-CS 

IMG-6294G APC 1D3 Rat M Flow-CS 

CD19 IMG-6321A Purified CB19 Mouse H Flow-CS, IF/ICC, IHC-Fr 

IMG-6321AF647 Alexa Fluor® 647 CB19 Mouse H Flow-CS, IF/ICC, IHC-Fr 

IMG-6321C FITC CB19 Mouse H Flow-CS 

IMG-6321D PE CB19 Mouse H Flow-CS, IF/ICC, IHC-Fr 

COX2 IMG-3130 PAP N/A Goat H WB 

COX2 IMG-80306 T.C. Sup. 4H12 Mouse H IHC-P 

COX2 IMG-80444 Purified N/A Rabbit H, M, R IHC-P 

Defensin-3 (bD-3) IMG-4090 Purified N/A Rabbit H WB 

ECSIT (CT) IMG-5618 Purified N/A Rabbit H, M WB 

GARP/LRRC32 IMG-6354A Purified N/A Rabbit Multi-species WB 

IFN-a IMG-209A Purified 144BS Mouse H ELISA, Flow-CS, IP 

IL-18BP IMG-4015 Purified N/A Rabbit H WB 

IRAK IMG-179 Purified N/A Rabbit H, M IP, WB 

IRAK (CT) IMG-5603 Purified N/A Rabbit H, M, R IP, WB 

IRAK-2 IMG-574 Purified N/A Rabbit H, M WB 

IRAK-2 (C2) IMG-5495 PAP N/A Rabbit M WB 

IRAK-2 (C2) IMG-5575 PAP N/A Rabbit H IF/ICC, WB 

IRAK-4 IMG-441 Purified N/A Rabbit H, M IP, WB 

IRAK-M IMG-5576 PAP N/A Rabbit H, M, R IHC-P, WB 

IRF3 (IN) IMG-5489 PAP N/A Rabbit H WB 

LPS Binding Protein IMX-5249 Sera N/A Rabbit H ELISA 

MD-1 IMG-357 Purified N/A Rabbit H, M IP, WB 

MD-2 IMG-5984A Purified N/A Rabbit H, M, R IHC-P, WB 

MD-2 (IN) IMG-5645 Purified N/A Rabbit H, M, R IHC-P, WB 

MEKK2 IMG-6017A Purified N/A Rabbit H IHC-P, WB 

MyD88 IMG-178 Purified N/A Rabbit H, M, R WB 

MyD88 IMG-3796 PAP N/A Goat H ELISA, IHC-P, WB 

MyD88 (CT) IMG-5499 PAP N/A Rabbit H, M, R WB 

MyD88 (IN) IMG-5579 PAP N/A Rabbit H IHC-P, WB 

8 



NALP2 IMG-6370A Purifi ed N/A Rabbit H IHC-P 

NALP5 IMX-6336 Sera N/A Rabbit H ELISA 

NALP7 IMG-6357A PAP N/A Rabbit Multi-species WB 


NOD1/CARD4 IMG-5224A Sera N/A Rabbit H WB 

NOD1/CARD4 IMG-5739 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

NOD2/CARD15 IMG-30161 PAP N/A Goat H WB 


NOD2/CARD15 IMG-5830 Purifi ed N/A Rabbit H WB 

NOD2/CARD15 IMG-5831 Purifi ed N/A Rabbit H WB 

Pellino 1 IMG-685 Sera N/A Rabbit H, M WB 

PGRP-1a IMG-391 Ascites 187C434 Mouse H Flow-CS, IF/ICC, WB 

PGRP-1b IMG-414 Purifi ed 186C426 Mouse H WB 

PGRP-S IMG-393 Purifi ed 188C424 Mouse H, M IF/ICC, WB 

PRAT4A IMG-6304A Sera N/A Rabbit H, M, R IHC-P 

RICK/RIP2 IMG-175 PAP N/A Rabbit H, M, R WB 

Toll-like Receptors Related antibodies 

• Detailed Protocols for 

TLR Immunobiology 

Studies 

• Overview of TLR Related 

Scientific & Market 

Sectors 

• Concepts of Host 

Immunity Against 

Pathogens 

• Milestones in the 

TLR Field 

IMGENEX & Innate Immunity: 

The Story Toll’d 

GET 

YOUR COPY 

NOW! 

For more details please call 

(888) 723-4363 or email 

info@imgenex.com 

• Mammalian TLRs 

• TLRs: Structure, Ligands, 

& Expression 

• TLRs as Immune Sentinels 

• TLRs as Bridges Between 

Innate & Adaptive Immunity 

• TLR Signaling Pathways 

• MyD88 Signaling 

• TLR Expression on Tregs 

• TLRs in Cell Survival & 

Death Pathways 

• TLRs and Immune Tolerane 

• Concepts of TLRs in 

Disease 

• TLRs in Stem Cells 

• TLRs in Therapeutics 

& Vaccines 




TLRSystem TM 9

antibodies 

Toll-like Receptors Related Proteins 


RIP1 

(IMG-6072A) 

Western blot analysis of 

human RIP1 in ramos cell 

lysate in the 1) absence and 

2) presence of immunizing 

peptide using IMG-6072A 

at 2 ug/ml. 

RIP1 IMG-6072A Purified N/A Rabbit H WB 

RIP3 IMG-5846A PAP Rabbit Chimp, H IHC-P, WB 

SARM (CT) IMG-5646 Purified N/A Rabbit H, M IF/ICC, WB 

SIGIRR IMG-517 Sera N/A Rabbit H WB 

SIGIRR (CT) IMG-5583 PAP N/A Rabbit H, M IF/ICC, WB 

ST2 (NT) IMG-5525 PAP N/A Rabbit M WB 

ST2/IL1RL1 IMG-6371A Purified N/A Rabbit Chimp, H IHC-P, WB 

ST2V IMG-6131A Purified N/A Rabbit H, M WB 

TAB1 IMG-5527 PAP N/A Rabbit H, M WB 

TAB182 IMX-3273 PAP N/A Goat ELISA 

TAK1 IMG-30071 PAP N/A Goat H WB 

TAK-1 IMG-424 Purified Rabbit H, M WB 

TAK-1 (NT) IMG-5528-1 PAP N/A Rabbit H, M, R WB 

TAK-1 (NT) IMG-5528-2 PAP N/A Rabbit H, M, R WB 

TBK1 (Phospho-S172) IMX-5194 Sera N/A Rabbit H ELISA 

TBK1/NAK IMG-139A Purified 108A429 Mouse Multi-species WB 

TBK1/NAK (CT) IMG-5501 PAP N/A Rabbit H, M WB 

TIR8 IMG-5086 Purified N/A Rabbit H, M WB 

TIRAP/Mal IMG-30013 PAP N/A Goat H WB 

TIRAP/Mal IMG-440 Ascites 20D1960.2.1 Mouse H WB 

TIRAP/Mal IMG-3326 PAP N/A Goat H WB 

TIRAP/Mal (CT) IMG-5647 Purified N/A Rabbit H, M, R IHC-P, WB 

TIRP (C2) IMG-5648 Purified N/A Rabbit H, M, R IHC-P, WB 

TNF-a IMG-224A Purified MP6-XT3 Rat M ELISA, ELISPOT, FA-Neut, WB 

TNF-a IMG-225A Purified MP6-XT22 Rat M ELISA, ELISPOT, WB 

IMG-225E Azide-Free MP6-XT22 Rat M ELISA, ELISPOT, Flow-Intra, WB 

TRAF6 IMG-536 PAP N/A Rabbit H, M WB 

TRAF6 IMG-5766 Sera N/A Rabbit Cow, H, M, R IHC-Fr, IHC-P, IP, WB 

TRAF6BP IMX-5056 Sera N/A Rabbit H, M ELISA 

TRAF6BP/TAX1BP IMG-5035 Purified N/A Rabbit H WB 

Tram IMX-5029 Sera N/A Rabbit H, M ELISA 

Tram IMX-5272 Purified N/A Rabbit H ELISA 

TRIAD3A IMG-5089A Purified N/A Rabbit H WB 

TRIAD3A IMG-5633 Purified N/A Rabbit M WB 

TRIF/TICAM1 IMG-5655 Purified N/A Rabbit H IHC-P, WB 

TRIF/TICAM1 IMG-661 Sera N/A Rabbit M WB 

TRIF/TICAM1 IMX-3075 PAP N/A Goat H ELISA 

TYRO3 IMG-6244A PAP N/A Rabbit H, M, R WB 

UBC13 IMG-5634 Purified N/A Rabbit H, M, R WB 

UEV1A IMG-5656 Purified N/A Rabbit H, M, R WB 

UNC93B IMG-6106A Purified N/A Rabbit H, M, R WB 

UNC93B IMX-6092 Sera N/A Rabbit M ELISA 

USP7 IMG-6391A Purified N/A Rabbit Multi-species WB 

USP7 IMG-6392A Purified N/A Rabbit Multi-species IHC-P, WB 

10 


antibodies 

Inflammation 


ACAP2 IMG-6355A PAP N/A Rabbit Multi-species WB 

AGAP2 IMG-6377A PAP N/A Rabbit Multi-species IHC-P, WB 

ARAP2 IMG-6381A Purified N/A Rabbit H IHC-P, WB 

Defensin-3 (bD-3) IMG-4090 Purified N/A Rabbit H WB 

FLAP (CT) IMG-3160 PAP N/A Goat H, M ELISA, IF/ICC 

LST1 IMX-6348 Sera N/A Rabbit H ELISA 

NALP1 IMX-6337 Sera N/A Rabbit Chimp, H ELISA 

NALP1 IMX-6338 Sera N/A Rabbit Multi-species ELISA 

NALP1 IMG-5734 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

NALP1 IMG-5735 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

NALP2/PAN1 IMG-6326A PAP N/A Rabbit H IHC-P, WB 

NALP2/PAN1 IMG-6370A Purified N/A Rabbit H IHC-P 

NALP2/PAN1 IMG-5741 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

NALP2/PAN1 IMG-5742 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

NALP2/PAN1 IMG-5832 Purified N/A Rabbit H, M, R WB 


NALP4/PAN2 IMX-6407 Sera N/A Rabbit Multi-species ELISA 

NALP4/PAN2 IMG-5743 Sera N/A Rabbit H, M IHC-Fr, IHC-P, IP, WB 




NALP7 IMX-6342 Sera N/A Multi-species ELISA 



NALP9 IMG-6375A Purified N/A Rabbit H WB 


NALP10 IMG-6366A Purified N/A Rabbit H WB 


NALP11 IMG-6443A Purified N/A Rabbit H IHC-P 



NALP12/PYPAF7 IMG-5744 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

NALP12/PYPAF7 IMX-6434 Sera N/A Rabbit H ELISA 

OPG IMG-103A Purified 98A1071 Mouse H IHC-P, WB 

Inflammation antibodies 

Spotlight on NALP1 (IMG-5735) 

A B C D 

Formalin-fixed, paraffin-embedded normal human tissue sections stained for NALP1 (CARD7/NAC) using IMG-5735 at 1:2000. A, epidermis. B, esophagus. 

C, uterine cervix. D, thymus. Hematoxylin-eosin counterstain. In A-C, NALP1 expression is associated with differentiation in stratified epithelial of the skin, 

esophagus, and cervix. 




TLRSystem TM 11

antibodies 

CD Markers 


CD14 

(IMG-6350H) 

Cell surface flow cytometric 

analysis of CD14 in 10^6 

human monocytes using 

10 ul of IMG-6350H. Green 

represents PerCP-Cy5.5 

conjugated isotype control 

(IMGENEX, 20109H); 

red represents anti-CD14 

antibody. IMGENEX’s cell 

surface flow kit (10084K) 

was used for this test. 

CCR1/CD191 IMG-329 Purified Rabbit H, M Flow-Intra, WB 

CCR1/CD191 IMG-332 Purified N/A Rabbit H, M, R WB 

CCR1/CD191 IMG-71206 PAP N/A Rabbit H IHC-P 

CD1a IMG-80264 T.C. Sup. O10 Mouse H IHC-P 

CD2 IMG-6296A Purified RPA-2.10 Mouse H FA-Neut, Flow-CS, IHC-Fr, WB 

CD2 IMG-6296AF488 Alexa Fluor® 488 RPA-2.10 Mouse H FA-Neut, Flow-CS, IHC-Fr, WB 

IMG-6296AF647 Alexa Fluor® 647 RPA-2.10 Mouse H FA-Neut, Flow-CS, IHC-Fr, WB 

CD3 IMG-5923A Purified 145-2C11 Hamster M Flow-CS 

IMG-5923C FITC 145-2C11 Hamster M Flow-CS 

IMG-5923D PE 145-2C11 Hamster M Flow-CS 

NEW 

IMG-5923E Azide Free 145-2C11 Hamster M Flow-CS 

IMG-5923G APC 145-2C11 Hamster M Flow-CS 

CD3 IMG-80081 T.C. Sup. PS1 Mouse H IHC-P 

CD3 IMG-80337 T.C. Sup. SP7 Rabbit Multi-species IHC-P, WB 

CD3 IMG-80354 Purified N/A Rabbit H IHC-P 

CD4 IMG-5922A Purified GK1.5 Rat M Flow-CS 

IMG-5922C FITC GK1.5 Rat M Flow-CS 

IMG-5922D PE GK1.5 Rat M Flow-CS 

NEW 

IMG-5922E Azide Free GK1.5 Rat M Flow-CS 

IMG-5922G APC GK1.5 Rat M Flow-CS 

CD4 (L3T4) IMG-5916A Purified RPA-T4 Mouse H FA-Neut, Flow-CS, IHC 

IMG-5916C FITC RPA-T4 Mouse H Flow-CS 

IMG-5916D PE RPA-T4 Mouse H Flow-CS 

NEW 

IMG-5916E Azide Free RPA-T4 Mouse H FA-Neut, Flow-CS, IHC 

IMG-5916G APC RPA-T4 Mouse H Flow-CS 

CD5 IMG-80086 T.C. Sup. 54/B4 Mouse H IHC-P 

CD5 IMG-80097 T.C. Sup. 4C7 Mouse H IHC-Fr, IHC-P 

CD5 IMG-80343 T.C. Sup. SP19 Rabbit H IHC-P 


CD8 IMG-5917A Purified RPA-T8 Mouse H Flow-CS 






CD11b IMG-6292A Purified 5C6 Rat M Flow-CS 

IMG-6292C FITC 5C6 Rat M Flow-CS 

IMG-6292D PE 5C6 Rat M Flow-CS 

IMG-6292G APC 5C6 Rat M Flow-CS 

CD11b IMG-6328A Purified 44aacb Mouse H Flow-CS 

IMG-6328AF647 Alexa Fluor® 647 44aacb Mouse H Flow-CS 

IMG-6328C FITC 44aacb Mouse H Flow-CS 

IMG-6328D PE 44aacb Mouse H Flow-CS 

12 



CD11c IMG-6293AF647 Alexa Fluor® 647 N418 Hamster M Flow-CS 

IMG-6293C FITC N418 Hamster M Flow-CS 

IMG-6293D PE N418 Hamster M Flow-CS 

CD14 IMG-3991 PAP N/A Goat H WB 

CD14 IMG-6350A Purified RPA-M1 Mouse H Flow-CS 

IMG-6350AF647 Alexa Fluor® 647 RPA-M1 Mouse H Flow-CS 

IMG-6350C FITC RPA-M1 Mouse H Flow-CS 

IMG-6350E Azide-Free RPA-M1 Mouse H Flow-CS 

NEW 

IMG-6350H PerCP-Cy5.5 RPA-M1 Mouse H Flow-CS 

CD16/32 IMG-6297A Purified 2.4G2 Rat M Flow-CS, Flow-Intra 

CD19 IMG-6294A Purified 1D3 Rat M Flow-CS 

IMG-6294C FITC 1D3 Rat M Flow-CS 

IMG-6294D PE 1D3 Rat M Flow-CS 

IMG-6294G APC 1D3 Rat M Flow-CS 

CD19 IMG-6321A Purified CB19 Mouse H Flow-CS, IF/ICC, IHC-Fr 

IMG-6321AF647 Alexa Fluor® 647 CB19 Mouse H Flow-CS, IF/ICC, IHC-Fr 

IMG-6321C FITC CB19 Mouse H Flow-CS 

IMG-6321D PE CB19 Mouse H Flow-CS, IF/ICC, IHC-Fr 

CD20 IMG-80017 T.C. Sup. L26 Mouse H IHC-Fr, IHC-P, WB 


CD23 IMG-80104 T.C. Sup. MHM6 Mouse H IHC-P 

CD23 IMG-80203 T.C. Sup. 1B12 Mouse H IHC-P 



CD25 IMG-5918A Purified 7G7B6 Mouse H Flow-CS 

IMG-5918C FITC 7G7B6 Mouse H Flow-CS 

IMG-5918D PE 7G7B6 Mouse H Flow-CS 

IMG-5918G APC 7G7B6 Mouse H Flow-CS 

IMG-5918H PerCP-Cy5.5 7G7B6 Mouse H Flow-CS 

CD25 IMG-5924A Azide-Free PC61 Rat M Flow-CS 

IMG-5924C FITC PC61 Rat M Flow-CS 

IMG-5924G APC PC61 Rat M Flow-CS 

CD25 IMG-80169 Purified IL2R.1 Mouse H IHC-Fr, IHC-P 

CD27 IMG-6542A Purified 203.6 Mouse H Flow-CS, IF/ICC, IHC-Fr 

NEW 

CD28 IMG-4038 Purified N/A Rabbit H WB 

CD34 IMG-80073 Purified QBEND/10 Mouse Multi-species IF/ICC, IHC-Fr, IHC-P, WB 

CD34 IMG-6540C FITC ICO-115 Mouse H Flow-CS, IF/ICC 

NEW 

CD35 IMG-80106 T.C. Sup. Ber-MAC-DRC Mouse H IHC-P 

CD40 IMG-5714 Sera N/A Rabbit Multi-species IHC-Fr, IHC-P, IP, WB 

CD43 IMG-80025 Purified DF-T1 Mouse H IHC-Fr, IHC-P 

CD44 IMG-80171 Purified 156-3C11 Mouse H IHC-P 

CD45 IMG-80026 T.C. Sup. 2B11&PD7/26 Mouse H IHC-Fr, IHC-P 

CD47 

(IMG-6581E) 

Cell surface flow cytometric 

analysis of CD47 on human 

peripheral blood lymphocytes 

using 0.5 ug/0.5x10^6 

cells of IMG-6581E. Green 

histogram represents isotype 

control (20109); red represents 

CD47 antibody. 

CD Markers antibodies 




TLRSystem TM 13

antibodies 

CD Markers 


CD207/Langerin 

(DDX0361PE) 

Intracellular flow analysis of 

Langerin in stably transfected 

CHO cells (A) or DC-SIGN 

in stably transfected HeLa 

cells (negative control) (B) 

using DDX0361PE at 1ug/ml. 

Blue histogram in both panels 

represents isotype control, red 

histogram is anti-Langerin. 

Total viable cells were used 

for analysis. 

CD45RA IMG-80027 T.C. Sup. 4KB5 Mouse H IHC-Fr, IHC-P 

CD45RO IMG-80029 Purified UCHL-1 Mouse H Flow-CS, IHC-Fr, IHC-P, IP, WB 

CD47 IMG-6581E Azide Free B6H12.2 Mouse H FA-Neut, Flow-CS, IP, WB 

NEW 

CD57/HNK-1 IMG-80109 Purified NK-1 Mouse H IHC-Fr, IHC-P, IP 

CD61 IMG-80110 T.C. Sup. Y2/51 Mouse H IHC-P 

CD68 IMG-80071 T.C. Sup. Pg-M1 Mouse H IHC-P 

CD68 IMG-80112 T.C. Sup. KP1 Mouse Multi-species IHC-Fr, IHC-P 



CD74 IMG-80113 Purified LN2 Mouse H IHC-Fr, IHC-P, IP, WB 

CD75 IMG-80114 Purified LN1 Mouse H IHC-Fr, IHC-P 

NEW 

CD79a IMG-80082 Purified HM57 Mouse H, Pig IHC-Fr, IHC-P 

NEW 

CD79a IMG-80161 Purified HM47/A9 Mouse Multi-species IF/ICC, IHC-P, IP, WB 

NEW 

CD79a IMG-80332 T.C. Sup. SP18 Rabbit Multi-species IHC-P 

CD86/B7-2 IMG-6582AF488 Alexa Fluor® 488 GL1 Rat M Flow-CS 

IMG-6582AF647 Alexa Fluor® 647 GL1 Rat M Flow-CS 

IMG-6582E Azide Free GL1 Rat M FA-Neut, Flow-CS, IF/ICC, 

IHC-Fr, IP 

CD100 IMG-6295A Purified A8 Mouse H Flow-CS, IP 

IMG-6295AF488 Alexa Fluor® 488 A8 Mouse H Flow-CS 

IMG-6295AF647 Alexa Fluor® 647 A8 Mouse H Flow-CS 

CD100/SEMA-4D IMG-4078 Purified N/A Rabbit H WB 

CD100/SEMA-4D IMG-4079 Purified N/A Rabbit H WB 

CD150 IMG-6541A Purified IPO-3 Rabbit H Flow-CS, IF/ICC, IHC-Fr, IP 

NEW 

CD207/Langerin IMG-5102A Purified N/A Rabbit M CM, IHC-Fr, WB 

CD207/Langerin DDX0361APC APC 310F7.02/HD26 Mouse H, M, R Flow-Intra, IHC-P 

DDX0361PE PE 310F7.02/HD26 Mouse H, M, R Flow-Intra, IHC-P 

CD274/B7-H1 IMG-3791 PAP N/A Goat H WB 

CD281/TLR1 IMG-5012 Purified N/A Rabbit H, M, R Flow-CS, Flow-Intra, WB 

NEW 

NEW 



CD281/TLR1 IMG-5629 Purified N/A Rabbit H, M WB 

CD282/TLR2 IMG-319 Ascites 1030A5.138 Mouse H Flow-CS, Flow-Intra, IHC-P, WB 

CD282/TLR2 IMG-410A Purified N/A Rabbit H, M IHC-P, WB 

IMG-410E Azide-Free N/A Rabbit H, M WB 

CD282/TLR2 IMG-416A Purified TL2.1 Mouse Dog, H Flow-CS+Intra, IF/ICC, IHC-P, 

IP, WB 

IMG-416AF488 Alexa Fluor® 488 TL2.1 Mouse Dog, H Flow-CS, Flow-Intra, IF/ICC 

IMG-416B Biotin TL2.1 Mouse Dog, H Flow-CS, Flow-Intra, IF/ICC, IP 

IMG-416C FITC TL2.1 Mouse Dog, H Flow-CS, Flow-Intra, IF/ICC 

IMG-416D PE TL2.1 Mouse Dog, H Flow-CS, Flow-Intra, IF/ICC 

IMG-416E Azide-Free TL2.1 Mouse Dog, H FA-Neut, Flow-CS, Flow-Intra, 

IF/ICC, IP 

CD282/TLR2 IMG-526 Purified N/A Rabbit H, M WB 

CD282/TLR2 IMG-545 Purified N/A Rabbit Multi-species WB 

IMG-545E Azide-Free N/A Rabbit Multi-species WB 

14 



CD282/TLR2 IMG-5651 Purified N/A Rabbit H, M IHC-P, WB 

CD282/TLR2 IMG-6320A Purified T2.5 Mouse H, M FA-Neut, Flow-CS, IHC-Fr, IP 

CD282/TLR2 IMG-662 Purified N/A Rabbit M WB 

CD283/TLR3 IMG-315A Purified 40C1285.6 Mouse Dog, H Flow-CS+Intra, IF/ICC, IHC-P, IP, WB 



IMG-315B Biotin 40C1285.6 Mouse Dog, H ELISA 

IMG-315C FITC 40C1285.6 Mouse Dog, H Flow-CS, Flow-Intra, IF/ICC 

IMG-315D PE 40C1285.6 Mouse Dog, H Flow-CS, Flow-Intra, IF/ICC 

CD283/TLR3 IMG-516 Purified N/A Rabbit M Flow-CS+Intra, IHC-Fr, IHC-P, WB 

IMG-516C FITC N/A Rabbit M Flow-CS, Flow-Intra 

CD283/TLR3 (CT) IMG-5631 Purified N/A Rabbit H, M WB 

CD283/TLR3 (Tyr759) IMG-5348A PAP N/A Rabbit H IF/ICC, IHC-Fr, WB 

CD284/TLR4 IMG-417A Purified HTA125 Mouse Dog, H CM, FA-Neut, Flow-CS+Intra, 

IF/ICC, IP 



IMG-417B Biotin HTA125 Mouse Dog, H CM, ELISA, FA-Neut, 

Flow-CS+Intra, IF/ICC, IP 

IMG-417C FITC HTA125 Mouse Dog, H Flow-CS, Flow-Intra 

IMG-417D PE HTA125 Mouse Dog, H CM, Flow-CS, Flow-Intra 

IMG-417E Azide-Free HTA125 Mouse Dog, H CM, FA-Neut, Flow-CS+Intra, 

IF/ICC, IP 

CD284/TLR4 IMG-428A Purified MTS510 Rat M Flow-CS, IP 

NEW 

IMG-428AF647 Alexa Fluor® 647 MTS510 Rat M Flow-CS 

IMG-428C FITC MTS510 Rat M Flow-CS 

IMG-428D PE MTS510 Rat M Flow-CS 

IMG-428E Azide-Free MTS510 Rat M FA-Neut, Flow-CS, IP 

CD284/TLR4 IMG-5031A Purified 76B357.1 Mouse H, M, R Flow-CS+Intra, IHC-P, WB 

IMG-5031AF488 Alexa Fluor® 488 76B357.1 Mouse H, M, R Flow-CS+Intra 

IMG-5031C FITC 76B357.1 Mouse H, M, R Flow-CS+Intra 

IMG-5031D PE 76B357.1 Mouse H, M, R Flow-CS+Intra 

CD284/TLR4 IMG-577 Purified N/A Rabbit H, M IP, WB 

CD284/TLR4 IMG-578A Purified N/A Rabbit H, M WB 

CD284/TLR4 IMG-579A Purified Rabbit H, M Flow-CS, IHC-Fr, IHC-P, WB 

CD284/TLR4 (Tyr674) IMG-6276A PAP Rabbit H, M, R WB 

CD286/TLR6 IMG-304A Purified 86B1153.2 Mouse H Flow-CS, IHC-P 



IMG-304B Biotin 86B1153.2 Mouse H ELISA 

IMG-304C FITC 86B1153.2 Mouse H Flow-CS+Intra 

IMG-304D PE 86B1153.2 Mouse H Flow-CS+Intra 

CD286/TLR6 IMG-5239 Sera Rabbit H IHC-P 

CD286/TLR6 IMG-527 Purified N/A Rabbit H, M Flow-Intra, WB 

CD Markers antibodies 




TLRSystem TM 15

antibodies 

CD Markers 


CD344/Frizzled-4 

(IMG-71274) 

CD286/TLR6 IMX-5260 Sera NA Rabbit H ELISA 

CD288/TLR8 IMG-321A Purified 44C143 Mouse H, M Flow-CS+Intra, IHC-P, WB 



CD288/TLR8 IMG-321B Biotin 44C143 Mouse H, M ELISA 

IMG-321C FITC 44C143 Mouse H, M Flow-CS+Intra 

IMG-321D PE 44C143 Mouse H, M Flow-CS+Intra 

CD288/TLR8 IMG-5653 Purified N/A Rabbit H, M IF/ICC, WB 

CD289/TLR9 IMG-305A Purified 26C593.2 Mouse Multi-species CM, Flow-CS+Intra, IF/ICC, 




IMG-305B Biotin 26C593.2 Mouse Multi-species ELISA 

IMG-305C FITC 26C593.2 Mouse Multi-species CM, Flow-CS+Intra, IF/ICC, 


CD289/TLR9 IMG-305D PE 26C593.2 Mouse Multi-species CM, Flow-CS+Intra, IHC-Fr, 

IHC-P 

IMG-305E Azide-Free 26C593.2 Mouse Multi-species CM, Flow-CS+Intra, IF/ICC, 


CD289/TLR9 IMG-431 Purified Rabbit H, M Flow-CS+Intra, IF/ICC, IHC-Fr, 

IHC-P, WB 

CD290/TLR10 IMG-386A Purified 158C1114 Mouse H Flow-CS+Intra, WB 

IMG-386C FITC 158C1114 Mouse H Flow-CS+Intra 

IMG-386D PE 158C1114 Mouse H Flow-CS+Intra 

CD290/TLR10 IMG-5255A Purified N/A Rabbit M, R ELISA, WB 

CD290/TLR10 IMX-5093 Purified N/A Rabbit H ELISA 

CD290/TLR10 (IN) IMG-5630 Purified N/A Rabbit H WB 

CD344/Frizzled-4 IMG-71273 PAP N/A Rabbit H IHC-P 

CD344/Frizzled-4 IMG-71274 PAP N/A Rabbit R IHC-P 

CD349/Frizzled-9 IMG-71284 PAP N/A Rabbit H IHC-P 

E-Cadherin IMG-80129 Purified 67A4 Mouse H FA-Neut, Flow-CS, IHC-Fr, WB 

Fas (CD95) IMG-80403 Purified N/A Rabbit H IHC-P 

FLT3 IMG-71999 PAP N/A Rabbit H IHC-P 

GITR IMG-5920A Purified DTA-1 Rat M Flow-CS, IP 

Leukocyte CD97 IMG-71178 PAP N/A Rabbit H IF/ICC, IHC-P 

Leukocyte CD97 IMG-71179 PAP N/A Rabbit H IHC-P 

Leukocyte CD97 IMG-71180 PAP N/A Rabbit H IF/ICC, IHC-P 

Slc7a5 IMG-71988 PAP N/A Rabbit H IHC-P 


Slc7a11 IMG-30309 PAP N/A Goat H WB 


IHC analysis of Kidney using 

IMG-71274 at 25 ug/ ml. 

16 


antibodies 

T Regulatory Cells 


CD3 IMG-5923A Purified 145-2C11 Hamster M Flow-CS 

IMG-5923C FITC 145-2C11 Hamster M Flow-CS 

IMG-5923D PE 145-2C11 Hamster M Flow-CS 

IMG-5923E Azide-Free 145-2C11 Hamster M FA-A, FA-D, Flow-CS 

IMG-5923G APC 145-2C11 Hamster M Flow-CS 

CD3 IMG-80315 T.C. Sup F7.2.38 Mouse H IHC-P 

CD3 IMG-80337 T.C. Sup SP7 Rabbit Multi IHC-P, WB 

CD3 e IMG-80449 Purified N/A Rabbit Multi IHC-P 

CD3 zeta IMG-80450 Purified N/A Rabbit H, M, R IHC-P 

CD3, T Cell IMG-80081 T.C. Sup PS1 Mouse H IHC-P 

CD3, T Cell IMG-80354 Purified N/A Rabbit H IHC-P 

CD4 IMG-5808A Purified NA Rabbit Chimp, H WB 

CD4 IMG-5922A Purified GK1.5 Rat M Flow-CS 

IMG-5922C FITC GK1.5 Rat M Flow-CS 

IMG-5922D PE GK1.5 Rat M Flow-CS 

NEW 

IMG-5922E Azide Free GK1.5 Rat M Flow-CS 

IMG-5922G APC GK1.5 Rat M Flow-CS 

CD4 IMG-80083 T.C. Sup 1F6 Mouse H IHC-P, WB 

CD4 (L3T4) IMG-5916A Purified RPA-T4 Mouse H FA-Neut, Flow-CS, IHC 



IMG-5916E Azide Free RPA-T4 Mouse H FA-Neut, Flow-CS, IHC 


CD8 IMG-5917A Purified RPA-T8 Mouse H Flow-CS 




CD8, T Cell IMG-80331 T.C. Sup 144B Mouse H IHC-P 

CD8, T Cell IMG-80344 T.C. Sup SP16 Rabbit H IHC-P 

CD8, T Cell IMG-80436 Purified N/A Rabbit H IHC-P 

CD25 IMG-5918A Purified 7G7B6 Mouse H Flow-CS 

IMG-5918C FITC 7G7B6 Mouse H Flow-CS 

NEW 

IMG-5918D PE 7G7B6 Mouse H Flow-CS 

IMG-5918G APC 7G7B6 Mouse H Flow-CS 

IMG-5918H PerCP-Cy5.5 7G7B6 Mouse H Flow-CS 

CD25 IMG-5924A Azide-Free PC61 Rat M Flow-CS 

IMG-5924C FITC PC61 Rat M Flow-CS 

IMG-5925D PE PC61 Rat M Flow-CS 

IMG-5924G APC PC61 Rat M Flow-CS 

CD25, IL2 Receptor IMG-80105 T.C. Sup ACT-1 Mouse H Flow-CS, IHC-Fr 

CD25, IL2 Receptor IMG-80169 Purified IL2R.1 Mouse H IHC-Fr, IHC-P 

CD38 IMG-80205 T.C. Sup AT13/5 Mouse H IHC-P 

CD45, LCA IMG-80026 T.C. Sup 2B11&PD7/26 Mouse H IHC-Fr, IHC-P 

CD45RA, B Cell IMG-80027 T.C. Sup 4KB5 Mouse H IHC-Fr, IHC-P 

CD45RB IMG-80172 T.C. Sup Bra-11 Mouse H IHC-P 

CD25 

(IMG-5918G) 

Flow analysis of CD25 in 10^6 

human PBMCs with 38 hour 

ConA stimulation (5 ug/ml) using 

10 ul of IMG-5918G. 

T Regulatorry Cells antibodies 




TLRSystem TM 17

antibodies 

T Regulatory Cells 


CD45RB IMG-80173 T.C. Sup DF-B1 Mouse H IHC-P 

CD45RB, LCA IMG-80028 T.C. Sup PD7/26 Mouse H IHC-P 

CD45RO, T Cell IMG-80029 Purified UCHL-1 Mouse H Flow-CS, IHC-Fr, IHC-P, IP, WB 

CD54/ICAM-1 IMG-80108 Purified 15.2 Mouse H Flow, IHC-Fr, IHC-P, WB 

CD62E/ELAM-1 IMG-80111 Purified 1.2B6 Mouse H, Pig Flow-CS, IHC-Fr, IHC-P, IP, WB 

Fas (CD95) IMG-240 Purified DX2 Mouse H Flow 

Fas (CD95) IMG-80403 Purified N/A Rabbit H IHC-P 

Folate Receptor 4 IMG-6217A Purified TH6 Rat M Flow-CS 

IMG-6217C FITC TH6 Rat M Flow-CS 

IMG-6217D PE TH6 Rat M Flow-CS 

IMG-6217E Azide Free TH6 Rat M Flow-CS 

IMG-6217G APC TH6 Rat M Flow-CS 

Folate Receptor 4 IMG-6218A Purified 12A5 Rat M Flow-CS 

IMG-6218C FITC 12A5 Rat M Flow-CS 

IMG-6218D PE 12A5 Rat M Flow-CS 

IMG-6218E Azide Free 12A5 Rat M Flow-CS 

IMG-6218G APC 12A5 Rat M Flow-CS 

FOXP3 IMG-5802A Purified 3G3 Mouse H, M Flow-Intra, WB 

IMG-5802C FITC 3G3 Mouse H, M Flow-Intra 

IMG-5802D PE 3G3 Mouse H, M Flow-Intra 

IMG-5802G APC 3G3 Mouse H, M Flow-Intra 

FOXP3D2 IMG-6018A Purified 10D4G6 Mouse H WB 

IMG-6018E Azide Free 10D4G6 Mouse H WB 

GITR IMG-5920A Purified DTA-1 Rat M Flow-CS 

IMG-5920C FITC DTA-1 Rat M Flow-CS 

IMG-5920D PE DTA-1 Rat M Flow-CS 

IMG-5920G APC DTA-1 Rat M Flow-CS 

GITRL IMG-5474 P, AP N/A Rabbit H, M WB 

GPR18 IMG-71505 P, AP N/A Rabbit H IHC-P 

NEW 

GPR83 IMG-5864A P, AP NA Rabbit Multi IHC-P, IHC-Fr, WB 

GPR83 IMG-5913A P, AP N/A Rabbit Multi IHC-P, IHC-Fr, WB 

Spotlight on FOXP3/Scurfin (IMG-5802) 

Flow cytometric analysis of FOXP3 in human PBMCs stimulated with anti-hCD3 

and rhIL-2 (IMR-248) for 48 hours using isotype control (left) and IMG-5802C 

(right) at 0.5 ug/10^6 cells. 

Flow cytometric analysis of FOXP3 in human PBMCs stimulated with anti-hCD3 

and rhIL-2 (IMR-248) for 48 hours using isotype control (left) and IMG-5802D 

(right) at 0.1 ug/10^6 cells. 

18 





GPR83 IMG-71561 P, AP N/A Rabbit H, M Flow-CS, IHC-P 


GRAIL/RNF128 IMG-6058A P, AP N/A Rabbit Multi WB 

IL-10 IMG-222B Biotin JES5-16E3 Rat M ELISA, Flow-Intra, WB 

IL-10 IMG-223A Purified JES5-2A5 Rat M ELISA, ELISPOT, WB 

IMG-223B Biotin JES5-2A5 Rat M ELISA, ELISPOT, WB 

IL-10 IMG-317A Purified JES3-9D7 Rat H ELISA, FA-Neut, Flow-Intra, WB 

IMG-317E Azide Free JES3-9D7 Rat H ELISA, FA-Neut, Flow-Intra, WB 

IL-10 IMG-318A Purified JES3-12G8 Rat H ELISA, IHC-Fr 

IL-17A IMG-6545A Purified 4K5F6 Mouse H Flow-Intra, WB 

IMG-6545A647 Alexa Fluor® 647 4K5F6 Mouse H Flow-Intra 

IMG-6545B Biotin 4K5F6 Mouse H Flow-Intra, WB, ELISA 

IMG-6545D PE 4K5F6 Mouse H Flow-Intra 

IL-33/IL-1F11 IMG-6016A P, AP N/A Rabbit Chimp, H WB 

Integrin, Alpha X IMG-72062 P, AP N/A Rabbit H IHC-P 

Integrin, Alpha X IMG-72063 P, AP N/A Rabbit H IHC-P 

NFATc1 IMG-4073 Purified N/A Rabbit H WB 

NEW 


NEW 

NFATc1 IMG-5101A Purified N/A Rabbit H WB 


PTPRC IMG-72065 P, AP N/A Rabbit H IHC-P 

Qa-1b IMG-6223A Purified 6A8.6F10.1A6 Mouse M Flow-CS 

ROR Gamma IMG-6013A P, AP N/A Rabbit Chimp, H IHC-P 

ROR Gamma IMG-71896 P, AP N/A Rabbit H IHC-P 

TGFb3 IMG-80481 Purified N/A Rabbit M, R IHC-P 

TIM-3/ HAVCR2 IMG-5284A Purified N/A Rabbit M WB 

TIM-3 IMG-6543A Purified F38-2E2 Mouse H Flow-CS 

NEW 

NEW 

NEW 

IMG-6543D PE F38-2E2 Mouse H Flow-CS 

IMG-6543E Azide Free F38-2E2 Mouse H Flow-CS 

T Regulatorry Cells antibodies 

Spotlight on IL-17 (IMG-6545) 

Intracellular flow cytometric analysis of IL-17A in 

human lymphocytes stimulated with PMA (5 ng/ml), 

Ionomycin (1 mM), and Brefeldin A (1X) for 5 hrs. 

Intracellular flow cytometric analysis of IL-17A in 

human PBMCs (lymphocytes) stimulated with PMA 

(5 ng/ml), 

Intracellular flow cytometric analysis of IL-17A in human 

PBMCs (lymphocytes) stimulated with PMA (5 ng/ml), 

Ionomycin (1 mM), and Brefeldin A (1X) for 5 hrs 




TLRSystem TM 19

antibodies 

NF-kB 


Caspase-1 

(IMG-5025) 

Formalin-fixed, paraffin-embedded 

section of human reactive 

lymph node stained for Caspase-1 

expression (IMG-5025) 

using a DAB chromogen and 

Hematoxylin counterstain. 

A20 IMG-161A Purified 59A426 Mouse H IP, WB 

ABIN-2 IMG-434 Purified N/A Rabbit H, M, R WB 

ACT1 IMG-284 Purified N/A Rabbit H WB 

AKT1 IMG-487 Purified N/A Rabbit H WB 

AKT1 IMG-5411 PAP N/A Rabbit H, M, R IHC-P, WB 

AKT1 (Ser473) IMG-187A Purified 104A282 Mouse H, M IP, WB 

AKT2 IMG-351 Ascites 95C657.1.2 Mouse H WB 

AKT2/3 IMG-421 Purified N/A Rabbit H WB 

AKT3 IMG-326 Purified 66C1247.1 Mouse H, M, R WB 

AKT3 IMG-3389 PAP N/A Goat H WB 

AKT3 IMG-355 Purified N/A Rabbit H, M, R WB 

ARAP1 IMX-6347 Sera N/A Rabbit Multi-species ELISA 

ATM (Ser1981) IMG-90221-1 PAP N/A Rabbit H, M IHC-P 

Bcl-3 IMG-497 Purified N/A Rabbit H WB 

BLyS/BAFF IMG-247 Purified N/A Rabbit H, M WB 

BLyS/BAFF IMG-5610 Purified N/A Rabbit H, M, R WB 

BMI1 IMX-6345 Sera N/A Rabbit Multi-species ELISA 

CARMA1/ CARD11 IMX-5160 Sera N/A Rabbit H ELISA 

CARMA1/ CARD11 IMX-5161 Sera N/A Rabbit H ELISA 

Caspase-1 IMG-5025 Purified N/A Rabbit H IHC-P, WB 

Caspase-1 IMG-5028 Purified 14F468 Mouse H, M IHC-P, WB 

CIKS/Act1 IMG-563 Purified N/A Rabbit H, M, R WB 

CIKS/Act1 (NT) IMG-5447 PAP N/A Rabbit H WB 

CUEDC2 IMG-6279A Purified N/A Rabbit Multi-species WB 

CUEDC2 IMG-6299A Purified N/A Rabbit H IHC-P 

ECSIT (CT) IMG-5618 Purified N/A Rabbit H, M WB 

eIF2a (Ab-51) IMG-90565-2 PAP N/A Rabbit H, M, R IHC-P, WB 

eIF2a (Ser51) IMG-90331-1 PAP N/A Rabbit H, M, R IHC-P, WB 

GSK3a (Ser21) IMG-90124-1 PAP N/A Rabbit H, M, R IHC-P, WB 

GSK3b (Ab-216) IMG-90581-2 PAP N/A Rabbit H, M, R WB 

GSK3b (Tyr216) IMG-90343-1 PAP N/A Rabbit H, M, R IHC-P, WB 

HDAC2 (Ab-394) IMG-90468-2 PAP N/A Rabbit H, M, R IHC-P, WB 

HDAC-4 (Ser632) IMG-90275-1 PAP N/A Rabbit H, M, R WB 

HDAC5 (Ab-498) IMG-90470-2 PAP N/A Rabbit H, M, R IHC-P, WB 

HDAC5 (Ser498) IMG-90276-1 PAP N/A Rabbit H, M, R IHC-P, WB 

HDAC8 (Ab-39) IMG-90471-2 PAP N/A Rabbit H IHC-P, WB 

HDAC8 (Ser39) IMG-90227-1 PAP N/A Rabbit H, M, R IHC-P 

HNLF IMG-5112A Purified N/A Rabbit M, H, R WB 

IKAP IMG-4047 Purified N/A Rabbit H WB 

IkBa IMG-127A Purified 6A920 Mouse H, M Flow-Intra, IHC-P, IP, WB 

IkBa IMG-5016 Purified N/A Rabbit H WB 

IkBa IMG-5270A Purified N/A Rabbit H WB 

IkBa IMX-5142 Sera N/A Rabbit H ELISA 

IkBa IMG-127B Biotin 6A920 Mouse H, M ELISA 

IkBa (Ser32/Ser36) IMG-156A Purified 39A1413 Mouse Multi-species ELISA, IP, WB 

IMG-156B Biotin 39A1413 Mouse Multi-species ELISA 

IkBa (Tyr305) IMG-5783 PAP N/A Rabbit H, M, R WB 

IkBa (Tyr42) IMG-5782 PAP N/A Rabbit H, M, R IP, WB 

20 



IkBa (Tyr42) IMX-5097 Purified N/A Rabbit Multi-species ELISA 

IkBa (cleavage specific) IMG-394 Purified 5D1623 Mouse H WB 

IkBe (Ser22) IMG-90284-1 PAP N/A Rabbit H, M IHC-P, WB 

IkBz (zeta) IMG-5098A Purified N/A Rabbit M WB 

IKKa (Ab-23) IMG-90454-2 PAP N/A Rabbit H, M, R IHC-P, WB 

IKKa (Thr23) IMG-90228-1 PAP N/A Rabbit H, M, R IHC-P, WB 

IKKa/IKK1 IMG-136A Purified 14A231 Mouse Multi-species Flow-Intra, IHC-P, IP, WB 

IKKa/IKK1 IMG-136AF488 Alexa Fluor® 488 14A231 Mouse Multi-species Flow-Intra 

IKKa/IKK1 (C1) IMG-5477 PAP N/A Rabbit H WB 

IKKa/IKK1 (C2) IMG-5478 PAP N/A Rabbit H WB 

IKKb/IKK2 IMG-129A Purified 10AG2 Mouse H, M Flow-Intra, IP, WB 

IKKb/IKK2 IMG-129AF488 Alexa Fluor® 488 10AG2 Mouse H, M Flow-Intra 

IKKb/IKK2 IMG-159A Purified 10A9B6 Mouse H, M IP, Flow-Intra , WB 

IKKb/IKK2 IMG-159AF488 Alexa Fluor® 488 10A9B6 Mouse H, M Flow-Intra 

IKKb/IKK2 (C3) IMG-5570 PAP N/A Rabbit H IF/ICC, WB 

IKKe/IKKi IMG-309 Purified N/A Rabbit H WB 

IKKe/IKKi/TBK1 IMG-270A Purified 72B587 Mouse H, M, R Flow-Intra, WB 

IKKg/IKK3/NEMO IMG-287A Purified 46B844 Mouse H Flow-Intra, WB 

IKKg/IKK3/NEMO IMG-324A Purified 72C627 Mouse H, M WB 

IMG-324B Biotin 72C627 Mouse H, M ELISA 

IKKg/IKK3/NEMO IMG-4044 Purified N/A Rabbit H WB 

IKKg/IKK3/NEMO IMG-4045 Purified N/A Rabbit H WB 

IKKg/IKK3/NEMO IMG-5480 PAP N/A Rabbit H, M, R WB 

IRAK IMG-179 Purified N/A Rabbit H, M IP, WB 

IRAK-2 IMG-574 Purified N/A Rabbit H, M WB 

IRAK-2 (C2) IMG-5495 PAP N/A Rabbit M WB 

IRAK-4 IMG-441 Purified N/A Rabbit H, M IP, WB 

IRAK-4 IMG-5488 PAP N/A Rabbit H WB 

IRS-1 (Ser639) IMG-90300-1 PAP N/A Rabbit H, M, R IHC-P 

JNK2 IMG-586 Purified N/A Rabbit H WB 

kB-Ras1 IMG-390 Purified 184C278 Mouse H WB 

Lck (Tyr393) IMG-90240-1 PAP N/A Rabbit H, M, R WB 

LST1 IMX-6348 Sera N/A Rabbit H ELISA 

MALT1 IMG-5110A Purified N/A Rabbit H WB 

MALT1 IMG-5745 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

MSK1 (Ab-376) IMG-90510-2 PAP N/A Rabbit H, M, R WB 

MyD88 IMG-178 Purified N/A Rabbit H, M, R WB 

MyD88 IMG-3796 PAP N/A Goat H ELISA, IHC-P, WB 

MyD88 (CT) IMG-5499 PAP N/A Rabbit H, M, R WB 

MyD88 (IN) IMG-5579 PAP N/A Rabbit H IHC-P, WB 








NFATc1 IMG-5101A Purified N/A Rabbit H WB 

NALP11 

(IMG-6443A) 

Immunohistochemical analysis 

of NALP11 in formalin-fixed, 

paraffin-embedded human liver 

tissue using an isotype control 

(top) and IMG-6443A (bottom) 

at 5 ug/ml. 

NF-kB antibodies 




TLRSystem TM 21

antibodies 

NF-kB 


TRAF6 

(IMG-5766) 

Formalin-fixed, paraffinembedded 

tissue sections 

stained for TRAF6 using 

IMG-5766 at 1:2000. Hematoxylin-eosin 

counterstain. 

A, mouse lymph node. B, 

mouse bone marrow. 


NF-kB (p50) IMG-5845A Purified N/A Rabbit Multi-species WB 

NF-kB (p50) IMG-5812A Purified 2J10D7 Mouse H IHC-P, WB 

NF-kB (p65) IMG-150A Purified 112A1021 Mouse H, M, R Flow-Intra, IHC-P, WB 

IMG-150B Biotin 112A1021 Mouse H, M, R ELISA 

NF-kB (p65) IMG-512 Purified N/A Rabbit H, M, R WB 

NF-kB (p65) IMG-5915A Purified N/A Rabbit Multi-species WB 

NF-kB (p65) IMG-80460 Purified N/A Rabbit Multi-species IHC-P 

NF-kB p65-NLS IMG-6066A PAP N/A Rabbit Multi-species IF/ICC, WB 

NIBP IMX-5896 Sera N/A Rabbit Multi-species ELISA 

NIK IMG-443 Purified N/A Rabbit H WB 

NOD1/CARD4 IMG-5224A Sera N/A Rabbit H WB 


NOD2/CARD15 IMG-30161 PAP N/A Goat H WB 


NOD2/CARD15 IMX-5053 Sera N/A Rabbit Multi-species ELISA 

OPG IMG-103A Purified 98A1071 Mouse H IHC-P, WB 

P38 MAPK (Thr180) IMG-90315-1 PAP N/A Rabbit H, M, R IHC-P 

P38 MAPK (Tyr182) IMG-90316-1 PAP N/A Rabbit H, M, R IHC-P, WB 

p50 NLS IMX-6200 Sera N/A Rabbit Multi-species ELISA 

p62dok IMG-177 Purified N/A Rabbit H, M WB 

p65 (Ser276/281) IMX-5238 Sera N/A Rabbit H ELISA 

p65-cleaved IMX-5098 Purified N/A Rabbit H, M, R ELISA 

p90RSK (Ab-348) IMG-90464-2 PAP N/A Rabbit H, M, R WB 

p90RSK (Ab-352) IMG-90465-2 PAP N/A Rabbit H, M, R WB 

p90RSK (Thr348) IMG-90208-1 PAP N/A Rabbit H, M, R IHC-P, WB 

PKCb (Thr642) IMG-90260-1 PAP N/A Rabbit H, M, R IHC-P, WB 

PKCz (Ab-1427) IMG-90589-2 PAP N/A Rabbit H, M, R IHC-P 

PKCz (Thr410) IMG-90349-1 PAP N/A Rabbit H, M, R IHC-P 

PKR (Ab-446) IMG-90566-2 PAP N/A Rabbit H, M IHC-P, WB 

PKR (Ab-451) IMG-90571-2 PAP N/A Rabbit H, M IHC-P 

PKR (Thr446) IMG-90332-1 PAP N/A Rabbit H, M IHC-P, WB 

PKR (Thr451) IMG-90337-1 PAP N/A Rabbit H, M IHC-P 

PLCg2 (Ab-753) IMG-90500-2 PAP N/A Rabbit H, M, R WB 

PLCg2 (Tyr753) IMG-90263-1 PAP N/A Rabbit H, M, R WB 

PRKR IMG-5120A Purified N/A Rabbit H WB 

PRKR IMX-5200 Sera N/A Rabbit M ELISA 



RANK/TNF11aR IMG-128A Purified 9A725 Mouse H, M Flow-CS, IHC-P, WB 

IMG-128D PE 9A725 Mouse H, M Flow-CS+Intra 

RANK/TNF11aR IMG-325A Purified 64C1385.1 Mouse H, M IP, WB 

RANK/TNF11aR IMG-5116A Purified N/A Rabbit M, H WB 

Relaxin Receptor 1 IMG-6184A Sera N/A Rabbit H IHC-P 

Relaxin Receptor 1 IMX-6184 Sera N/A Rabbit H ELISA 

RelB (Ab-552) IMG-90546-2 PAP N/A Rabbit H, M, R WB 

22 



RelB (Ser552) IMG-90318-1 PAP N/A Rabbit H, M, R IHC-P, WB 

RIP IMG-5747 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

SINTBAD/TBKBP1 IMG-6172A PAP N/A Rabbit H, M, R IHC-P, WB 

SINTBAD/TBKBP1 IMX-6119 Sera N/A Rabbit Multi-species ELISA 

TAK1 binding protein 3 IMG-5900A Purified N/A Rabbit Dog, H, M WB 

TAK-1/MAP3K7 IMG-424 Purified N/A Rabbit H, M WB 

TAK-1/MAP3K7 (NT) IMG-5528 PAP N/A Rabbit H, M, R WB 

TBK1 (Ser172) IMX-5194 Sera N/A Rabbit H ELISA 

TBK1/NAK IMG-139A Purified 108A429 Mouse Multi-species WB 

TBK1/NAK (CT) IMG-5501 PAP N/A Rabbit H, M WB 

TRADD IMG-5756 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

TRAF1 IMG-5757 Sera N/A Rabbit H IHC-Fr, IHC-P, IP, WB 

TRAF1 IMG-5758 Sera N/A Rabbit M IHC-Fr, IHC-P, IP, WB 

TRAF2 IMG-162 Purified 33A1293 Mouse H WB 

TRAF2 IMG-5759 Sera N/A Rabbit H, M, R IHC-Fr, IHC-P, IP, WB 


TRAF2 IMG-5761 Sera N/A Rabbit M IHC-Fr, IHC-P, IP, WB 

TRAF2 and TNIK IMG-71937 PAP N/A Rabbit H IF/ICC, IHC-P 

TRAF2 and TNIK IMG-71938 PAP N/A Rabbit H IHC-P 

TRAF3 IMG-535 Purified N/A Rabbit H, M WB 


TRAF3 IMG-5763 Sera N/A Rabbit Multi-species IHC-Fr, IHC-P, IP, WB 


TRAF5 IMG-163A Purified 55A219 Mouse H WB 


TRAF6 IMG-536 PAP N/A Rabbit H, M WB 


TRAF6 (CT) IMG-5654 Purified N/A Rabbit H, M, R IF/ICC, WB 

TRAF6BP/TAX1BP IMG-5035 Purified N/A Rabbit H WB 

TRAM IMG-5272A Purified N/A Rabbit Chimp, H, R. Mk IHC-P, WB 

Trance/RANKL IMG-133A Purified 12A668 Mouse H, M IHC-P, WB 

IMG-133B Biotin 12A668 Mouse H, M ELISA 

IMG-133E Azide-Free 12A668 Mouse H, M IHC-P, WB 

Trance/RANKL IMG-185A Purified 12A380 Mouse H, M Flow-CS, IHC-Fr, WB 

IMG-185D PE 12A380 Mouse H, M Flow-CS, IHC-Fr, WB 

Trance/RANKL IMG-5090A Purified N/A Rabbit M WB 

Trance/RANKL IMG-5108A Purified N/A Rabbit M WB 

TRIB3/SKIP3/SINK IMG-5118A Purified N/A Rabbit H WB 

Ubiquitin IMG-5021 Ascites Ubi-1 Mouse Multi-species IF/ICC, IHC-P, WB 

Ubiquitin IMG-80150 T.C. Sup. FPM1 Mouse H IHC-P 

Ubiquitin IMG-80385 Purified N/A Rabbit Multi-species IHC-P 

Ubiquitin IMG-5020 Sera N/A Rabbit Multi-species IF/ICC, WB 

Zap-70 (Ab-319) IMG-90491-2 PAP N/A Rabbit H, M, R IHC-P, WB 

Zap-70 (Ab-493) IMG-90492-2 PAP N/A Rabbit H, M, R IHC-P 

Zap-70 (Tyr319) IMG-90252-1 PAP N/A Rabbit H, M, R WB 

Zap-70 (Tyr493) IMG-90253-1 PAP N/A Rabbit H, M, R IHC-P 

Trance/RANKL 

(IMG-133A) 

Immunohistochemical 

staining of Trance/RANKL/ 

OPGL/ODF in formalin-fixed, 

paraffin-embedded human 

lymph node using IMG-133A 

at 5 ug/ml. Hematoxylineosin 

counterstain. 

NF-kB antibodies 




TLRSystem TM 23

antibodies 

Cytokines & Chemokines 


GPR81/FKSG80 

(IMG-71232) 

IHC analysis of Pituitary, 

Anterior using IMG-71232 at 

3 ug/ ml. 

Asb-2 IMG-502 Sera N/A Rabbit H WB 

Asb-11 IMG-504 Purified N/A Rabbit H WB 

BAFF-R (CT) IMG-5553 PAP N/A Rabbit H, M, R IHC-P, WB 

Bonzo (CT) IMG-5591 Purified N/A Rabbit H WB 

Bonzo (NT2) IMG-5430 PAP N/A Rabbit H WB 

CAMK 1D-b IMG-5008 Purified N/A Rabbit H WB 

CCR5 IMG-333 Purified N/A Rabbit H WB 

CCR10 IMG-286 Purified N/A Rabbit H Flow-Intra, IHC-Fr, WB 

CTRP2 IMG-5454 PAP N/A Rabbit H, M, R WB 

CTRP7 IMG-5463 PAP N/A Rabbit H, M, R WB 

CTRP7 (CT) IMG-5461 PAP N/A Rabbit H, M, R WB 

CX3CR1 IMG-183 Purified N/A Rabbit H, M, R IHC-P, WB 

CX3CR1 (EL) IMG-5464 PAP N/A Rabbit H WB 

CXCR1/CD191 IMG-329 Purified N/A Rabbit H, M Flow-CS, WB 

CXCR1/IL-8R A IMG-334 Purified N/A Rabbit H WB 

CXCR3 IMX-6202 Sera N/A Rabbit H Peptide ELISA* 

CXCR3 IMG-331A Purified N/A Rabbit H, M, R WB 

IMG-331E Purified N/A Rabbit H, M, R WB 

CXCR3 (CCR3) IMG-72169 PAP N/A Rabbit H IHC-P 

CXCR4/CD194 IMG-332 Purified N/A Rabbit H, M, R WB 

CXCR4 IMG-126 Purified N/A Rabbit H, M WB 

CXCR4 IMG-537 Purified N/A Rabbit H, M, R IHC-P, WB 

CXCR4 (NT) IMG-125 Purified N/A Rabbit H, M IF/ICC, WB 

CXCR5 IMG-327 Purified N/A Rabbit H WB 

EBI3 IMG-6100A Purified N/A Rabbit Chimp, H WB 

NEW 

Eotaxin (CT) IMG-5594 Purified N/A Rabbit H WB 

FAM3C IMG-5989A PAP N/A Rabbit Multi-species IHC-P, WB 

GPR81/FKSG80 IMG-71232 PAP N/A Rabbit H, R IHC-P 

GPR81/FKSG80 IMG-72204 PAP N/A Rabbit H IHC-P 

GPR81/FKSG80 IMG-72205 PAP N/A Rabbit H IHC-P 

GITRL IMG-5474 PAP N/A Rabbit H, M WB 

GM-CSF IMG-226A Purified MP1-22E9 Rat M ELISPOT, FA-Neut, Flow-Intra, 

IHC (cryosections), WB 

IMG-226E Azide-Free MP1-22E9 Rat M ELISPOT, FA-Neut, Flow-Intra, 

IHC (cryosections), WB 

GM-CSF IMG-227A Purified MP1-31G6 Rat M ELISPOT, IHC (cryosections), 

IP, WB 

IFN-a IMG-209A Purified 144BS Mouse H ELISA, Flow-CS, IP 

IFN-g IMG-210A Purified 43-11 Mouse H CITA, CLIA, FA-Neut 

IMG-210E Azide-Free 43-11 Mouse H CITA, CLIA, FA-Neut 

IL-1 Ra IMG-203A Purified 1.384 Mouse H CLIA, FA-Neut, IHC-Fr 

IL-1b IMG-212A Purified 1400.24.17 Rat M FA-Neut 

IMG-212E Azide-Free 1400.24.17 Rat M FA-Neut 

24 



IL-1RAcP (C1) IMG-5481 PAP N/A Rabbit H WB 

IL-1RAcP (C2) IMG-5482 PAP N/A Rabbit H WB 

IL-2 IMG-204A Purified N7.48A Mouse H Flow-Intra, IF/ICC, 

IHC (cryosections) 

IMG-204C FITC N7.48A Mouse H Flow-Intra, IF/ICC, 

IHC (cryosections) 

IL-4 IMG-206A Purified 4D9 Mouse H FA-Neut, IF/ICC, WB 

IMG-206E Azide-Free 4D9 Mouse H FA-Neut, IF/ICC, WB 

IL-4 IMG-207A Purified 8F12 Mouse H Flow-Intra, IF/ICC, WB 

IMG-207E Azide-Free 8F12 Mouse H FA-Neut, Flow-Intra, IF/ICC, WB 

IL-6 IMG-220A Purified MP5-20F3 Rat M ELISPOT, IF/ICC, IP 

IMG-220D PE MP5-20F3 Rat M ELISPOT, Flow-Intra, IF/ICC, IP 

IMG-220E Azide-Free MP5-20F3 Rat M ELISPOT, IF/ICC, IP 

IL-6 IMG-221A Purified MP5-32C11 Rat M ELISPOT, IF/ICC, IP 

IMG-221B Biotin MP5-32C11 Rat M ELISPOT, IF/ICC, IP 

IL-10 IMG-222B Biotin JES5-16E3 Rat M Flow-Intra, WB 

IL-10 IMG-223A Purified JES5-2A5 Rat M ELISPOT, WB 

IL-10 IMG-317A Purified JES3-9D7 Rat H FA-Neut, Flow-Intra, WB 

IMG-317E Azide-Free JES3-9D7 Rat H FA-Neut, Flow-Intra, WB 

IL-10 IMG-318A Purified JES3-12G8 Rat H IHC-Fr 

IL-17A IMG-6545A Purified 4K5F6 Mouse H Flow-Intra, WB 

NEW 

NEW 

NEW 

NEW 

IMG-6545A647 Alexa Fluor® 647 4K5F6 Mouse H Flow-Intra 

IMG-6545B Biotin 4K5F6 Mouse H Flow-Intra, WB, ELISA 

IMG-6545D PE 4K5F6 Mouse H Flow-Intra 

IL-17B/E R IMG-345A Purified 97C691 Mouse H WB 

IL-17B/E R IMG-470A Purified N/A Rabbit H WB 

IL-17E IMG-323A Purified 68C1039.2 Mouse H, M WB 

IL-18RA/AcPL IMG-5353A Purified NA Rabbit H, M WB 

IL-19 IMX-5182 Sera N/A Rabbit H Peptide ELISA* 


IL-20RA IMG-5226A Purified N/A Rabbit H, M WB 

IL-20RA IMX-5179 Sera N/A Rabbit H Peptide ELISA* 


IL-21 (IN) IMG-5572 PAP N/A Rabbit H IF/ICC, WB 

IL-21R IMG-547 Purified N/A Rabbit H WB 

IL-21R (NT) IMG-5484 PAP N/A Rabbit H, M, R WB 




IL-22R (NT) IMG-5573 PAP N/A Rabbit H, R IF/ICC, WB 

IL-23R IMG-5092A Purified N/A Rabbit H, M IHC-P, WB 

IL-23R IMX-5938 Sera N/A Rabbit Chimp, H Peptide ELISA* 

IL-24/MDA-7 

(IMG-5223A) 

Cell-surface flow cytometry 

analysis of IL-24 in Jurkat cells 

using IMG-5223A at 5 ug/10^6 

cells. The shaded histogram 

represents cells only, green 

represents isotype control, and 

purple represents anti-IL-24 

antibody. 

Cytokines & Chemokines antibodies 




TLRSystem TM 25

antibodies 

Cytokines & Chemokines 


p35/IL-12A 

(IMG-6105A) 

Western blot analysis of IL-12A 

in human brain lysate in the 1) 

absence, 2) presence of immunizing 

peptide, 3) mouse and 

4) rat using IMG-6105A at 2 ug/ 

ml, 0.5 ug/ml and 4 ug/ml. 

IL-24/MDA-7 IMG-5247A Sera N/A Rabbit H Peptide ELISA*, WB 

IL-24/MDA-7 IMG-5223A Purified N/A Rabbit H WB 

IL-27 IMG-5096A Purified N/A Rabbit H, M WB 

IL-27 IMX-5937 Sera N/A Rabbit Chimp, Dog, H Peptide ELISA* 

IL-27 IMX-5936 Sera N/A Rabbit Chimp, H Peptide ELISA* 

IL-32 IMX-5871 Purified N/A Rabbit H Peptide ELISA* 


IRF3 (IN) IMG-5489 PAP N/A Rabbit H WB 

p35/IL-12A IMG-6105A Purified N/A Rabbit Multi-species WB 

NEW 

PHAPI2/APRIL IMG-5551 PAP N/A Rabbit H, M IHC-P, WB 

RAPTOR IMG-5322A Sera N/A Rabbit M, H WB 

RAPTOR IMX-5086 Sera N/A Rabbit M Peptide ELISA* 

RAPTOR IMX-5319 Sera N/A Rabbit Multi-species Peptide ELISA* 


RAPTOR IMX-5321 Sera N/A Rabbit H Peptide ELISA* 


Rictor IMG-5323A Purified NA Rabbit H WB 

Rictor IMX-5324 Sera NA Rabbit Multi-species Peptide ELISA* 

Rictor IMX-5325 Sera NA Rabbit Multi-species Peptide ELISA* 

Rictor IMX-5326 Sera NA Rabbit H Peptide ELISA* 

SDF-1 IMX-6118 Sera N/A Rabbit H Peptide ELISA* 

SMAD3 IMG-5848A Purified Rabbit Multi-species IHC-P, WB 

SOCS1 IMG-501 Sera N/A Rabbit H, M WB 

SOCS5 IMG-503 Purified N/A Rabbit M, H WB 

ST2/IL1RL1 IMG-6371A Purified N/A Rabbit Chimp, H IHC-P, WB 

STAT1a/b IMG-280 Purified N/A Rabbit Multi-species WB 

STAT2 IMG-291 Purified N/A Rabbit H WB 

STAT3 IMG-30136 PAP N/A Goat H WB 

STAT3 IMG-3095 PAP N/A Goat H IHC-P, WB 

STAT4 IMG-461 Purified N/A Rabbit M, R WB 

STAT5b IMG-292 Purified N/A Rabbit H WB 

STAT6 IMG-462 Purified N/A Rabbit H WB 

STAT6 IMG-6249A Purified N/A Rabbit H, M, R IF/ICC, WB 

STAT6 IMX-5057 Sera N/A Rabbit H, M, R Peptide ELISA* 

STAT6 (Tyr641) IMG-408A Purified 177C322 Mouse H, M IP, WB 

TIR8 (Toll/IL-1R8) IMG-5086 Purified N/A Rabbit H, M WB 

Tis7 IMG-6301A Purified N/A Rabbit Multi-species IHC-P, WB 

TNF-a IMG-224A Purified MP6-XT3 Rat M ELISPOT, FA-Neut, WB 

TNF-a IMG-225A Purified MP6-XT22 Rat M ELISPOT, WB 

IMG-225B Biotin MP6-XT22 Rat M ELISPOT, WB 

IMG-225E Azide-Free MP6-XT22 Rat M ELISPOT, Flow-Intra, WB 

26 


antibodies 

New Additions 


CLIM1/PDLIM1 IMG-5847A Purified, P AP N/A Rabbit H, R. Mk WB 

TRF2 IMG-124A Purified 4A794.15 Mouse Multi-species ChIP, Flow-Intra, IF/ICC, 

IHC-Fr, IP, WB 

IMG-124AF488 Alexa Fluor® 488 4A794.15 Mouse Multi-species Flow-Intra 

IMG-124AF647 Alexa Fluor® 647 4A794.15 Mouse Multi-species Flow-Intra 

SSEA-1 IMG-6522A Purified MC-480 Mouse H,M FC, IHC, IP, WB 

IMG-6522B Biotin MC-480 Mouse H,M FC, IHC, IP, WB 

IMG-6522AF488 Alexa Fluor® 488 MC-480 Mouse H,M ICC, FC 

IMG-6522AF647 Alexa Fluor® 647 MC-480 Mouse H,M ICC, FC 

SSEA-3 IMG-6523A Purified MC-631 Rat H,M FC, IHC, IP, WB 

IMG-6523B Biotin MC-631 Rat H,M FC, IHC, IP, WB 

IMG-6523AF488 Alexa Fluor® 488 MC-631 Rat H,M ICC, FC 

SSEA-4 IMG-6524A Purified MC-813 Mouse H FC, IHC, IP, WB 

IMG-6524B Biotin MC-813 Mouse H FC, IHC, IP, WB 

IMG-6524C FITC MC-813 Mouse H ICC, FC 

IMG-6524AF647 Alexa Fluor® 647 MC-813 Mouse H ICC, FC 

IMG-6524D PE MC-813 Mouse H ICC, FC 

Tra-1-60 IMG-6525A Purified TRA-1-60R Mouse H FC, IHC, IP, WB 

IMG-6525B Biotin TRA-1-60R Mouse H FC, IHC, IP, WB 

IMG-6525AF488 Alexa Fluor® 488 TRA-1-60R Mouse H ICC, FC 

IMG-6525AF647 Alexa Fluor® 647 TRA-1-60R Mouse H ICC, FC 

Tra-1-81 IMG-6526A Purified TRA-1-81 Mouse H FC, IHC, IP, WB 

IMG-6526B Biotin TRA-1-81 Mouse H FC, IHC, IP, WB 

IMG-6526AF488 Alexa Fluor® 488 TRA-1-81 Mouse H ICC, FC 

IMG-6526AF647 Alexa Fluor® 647 TRA-1-81 Mouse H ICC, FC 

ActivELISA and ActivAssay Kits 

Description 

Phospho-IkBa ActivELISA TM Kit 

NF-kB/p65 ActivELISA TM Kit 

HID5/Psoriasin/S100A7 ActivELISA TM Kit 

COX Activity Assay Kit 

NOS Activity Assay Kit 

Interleukin-1b (human) EIA Kit 

Prostaglandin E 2 

EIA Kit - Monoclonal 

Interleukin-1a (human) EIA Kit 

His-Expression Detection Kit 

TNF-a (human) EIA Kit 

TNF-a (mouse) EIA Kit 

Cat No 

IMK-501 

IMK-503 

IMK-514 

IMK-516 

IMK-517 

IMK-518 

IMK-519 

IMK-520 

IMK-521 

IMK-522 

IMK-523 




TLRSystem TM 27

NF-kB Pathway Inhibitory Peptides 

Inhibiting NF-kB Signaling Pathways 

Cat No 

Description 

IMG-2000 IKKg NEMO Binding Domain (NBD) Inhibitory Peptide Set Functions as an IKKa/IKKb decoy by binding to 

IKKg NBD, thereby preventing formation of the 

IKK complex. 

IMG-2001 NF-kB p65 (Ser276) Inhibitory Peptide Set Functions as a p65 decoy through phosphorylation 

of the Ser276 site on the peptide. 

IMG-2002 TRAF6 Inhibitory Peptide Set Functions as a TRAF6 decoy by binding to the 

T6DP motif of RANK, thereby preventing binding 

of RANK to TRAF6. 

IMG-2003 NF-kB p65 (Ser529/536) Inhibitory Peptide Set Functions as a p65 decoy through phosphorylation 

of the Ser529/536 sites on the peptide. 

IMG-2004 NF-kB p50 (NLS) Inhibitory Peptide Set Functions as a p50 decoy by blocking the 

intracellular recognition mechanism of p50 NLS. 

IMG-2005 MyD88 Homodimerization Inhibitory Peptide Set Functions as a decoy by binding to the MyD88 

TIR domain. 

IMG-2006 TIRAP Inhibitory Peptide Set Functions as a TIRAP decoy by binding to 

TIR interacting domains on specific TLR receptors. 

28 



TLR/HEK 293 Stable Cell Lines 

Pathogen 

TLR/NF-kB/SEAPorter TM 

HEK 293 Stable Cell Lines 

MD-2 


TBK1 

IKKe/ 

IKKi 

Interferons 

IRF3 

IRF3 

p50 p65 

PAMP 

TRIF 

TRAM 

IKKa 

IKKg 

TLRs 

IKKb 

DAMP 

MyD88 

IRAK4 

IRAK1 

p50 p65 

Proinflammatory 

Cytokines/ 

Chemokines 

IkB 

TRAF6 

IkB 

Dissociation 

TLR5 

TLR7 

TLR8 

TLR9 

or 

TLR11 

MyD88 

AP-1 

TIRAP 

TLR2 

IRAK1/4 

MAPKs 

MyD88 

TRAF6 

TLR1 

or 

IKKs 

NF-kB 

TLR6 

IkB 

TIRAP 

SEAP 

MyD88 

CD14 

NF-kB 

TRIF 

TLR4 

TRAM 

TBK1 

IRF-3 

IKKe 

TLR3 

TRIF 

IMGENEX, the industry leader in Innate Immunity and Immune Signaling 

Pathways, introduces a complete and extensively validated set 

of human Toll-like Receptor (TLR) Cell Lines: HEK 293 cells stably 

transfected with unique and original plasmids for human TLR1, TLR2, 

TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, and TLR9. Designed for 

studying TLR expression and functional analysis, each TLR cell line 

has been validated with extensive functional testing. These products 

are the most optimized and advanced cell lines currently available. 

Features 

• Optimized TLR Expression 

• Extensive Functional Validation 

• Flexible and Advanced Research Tools 

• Convenience 

TLR/HEK 293 Stable Cell Lines 

Cat. No. 

IML-201 

IML-202 

IML-203 

IML-204 

IML-205 

IML-206 

IML-207 

IML-208 

IML-209A 

IML-209B 

IML-200 

Product 

TLR1 

TLR2 

TLR3 

TLR4 

TLR5 

TLR6 

TLR7 

TLR8 

TLR9 

TLR9 

Negative Control Vector 

IMGENEX, the industry leader in Innate Immunity and Immune Signaling 

Pathways, introduces SEAPorter Cell Lines: HEK 293 cells 

stably co-transfected with human Toll-like Receptor (TLR) and NF-kB 

reporter genes. Immediately available are TLR2, TLR3, TLR4, TLR5, 

TLR7, and TLR8 cell lines and TLR9 cell lines will be available shortly. 

Stable TLR/NF-kB/SEAPorter HEK 293 cell lines are designed for 

sensitivity, broad working range dynamics and applicable for High- 

Throughput Screening for TLR agonists and antagonists. 

Features 

• Optimized TLR & NF-kB Expression 

• Validated Cell Line Efficacy 

• Fast & Flexible 

• High-Throughput 

• Convenience 

TLR/NF-kB/SEAPorter TM HEK 293 Stable 

Cell Lines 

Cat No. 

IML-101 

IML-102 

IML-103 

IML-104 

IML-105 

IML-107 

IML-108 

Product 

NF-kB SEAPorter 

TLR2/NF-kB/SEAPorter 









TLRSystem TM 29

Screening Services for Inflammation & 

Immune Signaling Pathways 

IMGENEX is a recognized leader in the provision of 

tools for studying cellular responses. We have experience 

in the manufacturing of reagents and development 

of applications and assay systems for studying pathways 

of cellular response, particularly pathways related to Immune 

Receptors with a focus on Toll-like Receptors. Over 

the past several years IMGENEX has developed a broad 

product portfolio in the area of Toll-like Receptors (TLRs), 

and related areas of Inflammation and Immunology providing 

advanced research tools to accelerate the increasing 

volume of applied research in these areas of biology. 

In parallel with their critical role in shaping and regulating 

cellular and immune responses, is the recognition 

of Toll-like Receptors as tunable targets to control 

these responses. Identifying new, more specifi c and 

more potent TLR agonists or antagonists is an area of 

focus for companies with intent for commercial development 

of diagnostics for monitoring response, or interested 

in therapeutics as prophylactic or curative drugs. 

To help meet these objectives we now offer our new IM- 

GENEX Screening Services as a partner with expertise in 

cell signaling areas, as evidenced by the portfolio of products 

already commercialized. We are recognized as authorities 

in cell signaling pathways especially in the area 

of NF-kB related signaling pathways which are directly 

related to Infl ammation and Immune Signaling Pathways. 

Through IMGENEX Screening Services our objective is 

to become your partner in accelerating your research 

and product development efforts and meeting your specifi 

c objectives effi ciently and economically in accord with 

the scope, resources, and timetable structure desired. 

Partnering 

Information & 

Initiation of IMGENEX 

Screening Services 

Project 

Contact IMGENEX 

1Screening Services 

Tel: 858-642-0978 x 244 

Toll-Free: 888-723-4363 x 224 

info@imgenex.com 

Assurance of 

2Confidentiality 

Exchange NDA assures confi - 

dentiality 

Discussion of 

3Overall Project 

Project Scope, Timetable, 

Objectives 

IMGENEX provides SOW- 

4Statement of Work 

Systems, Assays, Reagents 

Planned 

Data Analysis Formats and 

Requirements 

PATHWAY PROFILING ANTIBODIES & REAGENTS FOR CELL BIOLOGY AND IMMUNOLOGY 

NF-κB SEAPorter Assay Kit 

(Cat. No. IMK-515) 

The IMGENEX NF-κB SEAPorter 

Assay Kit is designed to provide a flexible 

read-out system for the measurement of 

NF-κB activation, by ELISA compatible 

techniques, via quantitative measurement 

of secreted alkaline phosphatase in cell 

supernatants. 

The NF-κB SEAPorter 

Assay Kit offers 

• High-throughput screening 

• Convenient 96 well format 

• Choice of cells 

• Start to finish in as little as 1 hour 

• Complete with reagents including 

plasmids containing SEAP cDNA, 

buffers, and substrate. 

TLR5 

TLR7 

TLR8 

TLR9 

or 

TLR11 

MyD88 

AP-1 

TIRAP 

TLR2 

IRAK1/4 

MAPKs 

MyD88 

TRAF6 

IKKs 

NF-κB 

TLR1 

or 

TLR6 

TIRAP 

MyD88 

MD-2 

CD14 

IκB NF-κB 

SEAP 

TRIF 

NF-κB Transfected HEK 293 

Stable Cells (Cat. No. IML-101) 

TLR4 

TRAM 

TBK1 

IRF-3 

IKKε 

TLR3 

TRIF 

IMGENEX now provides 

cells which are stably 

transfected with an 

NF-κB inducible 

secreted alkaline 

phosphatase genedesigned 

as an optimal 

choice of cells for 

our new SEAPorter TM 

Assay Kit. 

TLR & Inflammatory Ligand 

Discovery Screen 

• Identifi cation of TLR ligands in cell culture 

• Identifi cation of TLR ligands in tissue fl uids 

• Identifi cation of TLR specifi c ligands 

TLR & Inflammatory Ligand 

Activation Screen 

• Pathway Analysis 

• Activation Potential 

Timetable & Milestones 

Quotation Presentation 

In Depth Discussion and 

5Project Review 

Review and revise SOW 

as agreed upon 

Agreement and 

6Go Ahead 

Start partnering with 

IMGENEX 

Choose from the extensive IMGENEX product offering of reagents and pathways involved in NF-κB activation to optimize your own bioassay 

and screening systems. Please monitor our website for new releases of NF-kB, TLR, and related screening products. 

RECEPTOR 

Related Products 

TLR3 

TLR Ligands TLR4 

Description 

Pam 3 Csk 4 - TLR1/2 Ligand 

Poly (I). Poly (C) - TLR3 Ligand 

LPS - TLR4 Ligand 

Flagellin - TLR5 Ligand 

MALP 2 - TLR6 Ligand 

Imiquimod - TLR7 Ligand 

CpG - TLR9 Ligand 

PATHWAY 

ELISA Kits 

Description 

Phospho-IκBα ActivELISA Kit 

NF-κB/p65 ActivELISA Kit 

READ-OUT 

IRF3 

TLR7 

TLR8 

TLR9 

IRF7 

TLR2 

TLR3 

IL-1 

Cat. No. 

IMG-2201 

IMG-2203 

IMG-2204 

IMG-2205 

IMG-2206 

IMG-2207 

IMG-2209H 

ROS 

Cat. No. 

IMK-501 

IMK-503 

IL-1 

IL-1 

TLR1 TLR7 

TLR2 TLR8 TLR3 

TLR4 TLR9 

Inhibitory PeptidesTLR4 

TLR5 TLR10 TLR5 

TLR6 Description TLR11 

IL-1 IKKγ NEMO Binding Domain 

NF-κB p65 (Ser276) 

NF-κB p65 (Ser529/536) 

NF-κB p50 

MyD88 

TIRAP 

NOD1 NOD2 TLR2 

Please visit our website at www.imgenex.com for more 

information on the NF-κB SEAPorter Assay Kit and 

NF-κB transfected HEK 293 stable cells. 

IRF3 IRF7 ROS CRE-AP-1 NF-kB 

11175 Flintkote Ave., Ste. E San Diego, CA 92121 Toll free: (888) 723-4363 Fax: (858) 642-0937 Info email: info@imgenex.com 

P13K 

MyD88 

RIP1 

NOD1 

NOD2 

RIP2 TRAF6 TRAF2 

Cat. No. 

IMG-2000 

IMG-2001 

IMG-2003 

IMG-2004 

IMG-2005 

IMG-2006 

TLR & Inflammatory Pathway Analysis 

• Mediator Cascade Analysis 

• Cytokines 

• Chemokines 

• Prostaglandins 

• Interferons 

30 


www.imgenex.com 

11175 Flintkote Avenue, Suite E 

San Diego, CA 92121 

Toll-free (888) 723-4363 

Fax (858) 642-0937 

Email info@imgenex.com 

www.imgenex.com

Immunology & Inflammation

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