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Haematologica 2003 - Supplements

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Figure1<br />

100%<br />

80%<br />

60%<br />

40%<br />

20%<br />

0%<br />

Time-To-Event Outcomes: UARK 98-026<br />

Patients with Follow-up, Data as of 03/04/03<br />

Overall Survival<br />

Event-Free Survival<br />

Events / N<br />

82 / 541<br />

120 / 541<br />

4-Year<br />

Estimate<br />

69% (61,76)<br />

62% (55,68)<br />

0 1 2 3 4 5<br />

Years from Start of Protocol Therapy<br />

Cytogenetic abnormalities (CA), present in 35%, imparted poor<br />

prognosis. Thus, OS and EFS were superior in the absence of CA<br />

(4yr OS 83% and 4yr EFS 82%); however, in the presence of<br />

CA13 or hypodiploidy, 4yr OS was only 41% and 4yr EFS 37%;<br />

an intermediate survival was observed in patients with “other<br />

CA” (4yr OS 59%, 4yr EFS 57%) (all p

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