atrial fibrillation and stroke prevention - Continuing Medical ...
atrial fibrillation and stroke prevention - Continuing Medical ...
atrial fibrillation and stroke prevention - Continuing Medical ...
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Essentials in Primary Care Conference<br />
Wednesday, July 31, 2013<br />
RE-LY<br />
Time to First Stroke/Systemic Embolism<br />
0.05-<br />
Warfarin<br />
Dabigatran 110 mg<br />
Dabigatran 150 mg<br />
H<br />
R<br />
RR = 0.91<br />
p < 0.001 (NI)<br />
P< 0.034<br />
(Sup)<br />
RR = 0.66<br />
(95% CI: 0.53-<br />
0.82)<br />
p < 0.001 (NI)<br />
P< 0.001<br />
(Sup)<br />
0.04-<br />
0.03-<br />
0.02-<br />
0.01-<br />
0.00-<br />
0 6 12 18 24 30<br />
Months<br />
Connolly SJ et al. NEJM 2009;361:1139-51<br />
RE-LY: Major Bleeding<br />
p=0.31<br />
%<br />
major<br />
bleed<br />
3.5-<br />
3.0-<br />
2.5-<br />
2.0-<br />
1.5-<br />
1.0-<br />
0.5-<br />
p=0.003<br />
3.36%<br />
2.71%<br />
3.11%<br />
warfarin<br />
dabigatran<br />
110 mg bid<br />
dabigatran<br />
150 mg bid<br />
Connolly SJ et al. NEJM 2009;361:1139-51<br />
Jan Basile, MD<br />
Atrial Fibrillation & Stroke Prevention
Change language