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Surgical Site Infection and the Operating Room Checklist - Safer ...

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Prophylaxis Dosing<br />

• Consider <strong>the</strong> upper range of doses for large<br />

patients<br />

- Gastroplasty: SSI rates 16.5% vs 5.6% 1<br />

• Repeat doses for long operations (> 4 hours)<br />

- Cardiac surgery: SSI rates 16% vs 7% 2<br />

1<br />

Forse, R; Karam, B; Maclean, D; Cristou, N. Antibiotic prophylaxis for surgery in morbidly obese patients. Surgery, 1989, 106: 750-7<br />

2<br />

Zanetti et al., Emerg Infect Dis, 2001

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