Surgical Site Infection and the Operating Room Checklist - Safer ...
Surgical Site Infection and the Operating Room Checklist - Safer ...
Surgical Site Infection and the Operating Room Checklist - Safer ...
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Current Approaches: Prevention of SSIs<br />
Multiple studies have shown that CHG <strong>and</strong> CHG/alcohol<br />
solutions display <strong>the</strong>se important properties:<br />
•CHG plus 70% isopropyl alcohol (IPA) has demonstrated<br />
efficacy against a wide range of bacteria, including P.<br />
aeruginosa, S. aureus, <strong>and</strong> antibiotic-resistant bacteria.<br />
•CHG/IPA exhibits a rapid onset of action, persists for up to<br />
24 hours, <strong>and</strong> has increased efficacy with repeated<br />
applications.<br />
•Chlorhexidine is not inactivated in <strong>the</strong> presence of blood,<br />
which neutralizes <strong>the</strong> effects of iodine <strong>and</strong> PCMX <strong>and</strong> dilutes<br />
<strong>the</strong> effects of alcohol.<br />
Florman et al. Current Approaches for <strong>the</strong> Prevention of SSIs. Am J Infect Dis. 3(1):51-61, 2007.
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