Vol 27 No 2 December - The Indian Society for Parasitology

102 Red cell genetic defects and malaria
JPD : Vol. 27 (2), 2003
Table II : Plasmodium falciparum parasite density in subjects of red cell genetic defects
S.
3
Incidence (%) of parasite density (per mm )
No. Genetic defects Very mild Mild Moderate Severe
(1-999) (1000-9999) (10000-49999) (>50000)
1. Sickle cell trait
d
7
c
6
a
3
a
-
(Hb-AS) (43.75) (37.50) (18.75) (0.00)
b
b
2. β-thalassaemia 10 8 6 1
(trait or minor) (40.00) (32.00) (24.00) (4.00)
3. G-6-PD deficiency 28
c
b
23 18 5
d
(G ) (37.84) (31.08) (24.32) (6.76)
4. Control or Normal 18 17 22 13
(without genetic (25.71) (24.29) (31.43) (18.57)
defects)
Figures in parentheses represent percentage
Superscripted alphabets denote level of satistically significant differences of genetic defects values compared with
the controls in the corresponding group. a, b, c, d = Significant at p < 0.001, p < 0.005, p < 0.025 and p < 0.05
respectively.
Table III : Plasmodium vivax parasite density in subjects of red cell genetic defects
3 2
S. Incidence (%) of parasite density (per mm ) χ
No. Genetic defects Very mild Mild Moderate Severe
(1-999) (1000-9999) (10000-49999) (>50000)
1. Sickle cell trait
a
3
c
4
a
3
c
1
(Hb-AS) (27.27) (36.36) (27.27) (9.09)
2. β-thalassaemia
c
5
d
5
b
5
c
1
(trait or minor) (31.25) (31.25) (31.25) (6.25)
3. G-6-PD deficiency 10
d
10 11 3
d
(G ) (29.41) (29.41) (32.35) (8.82)
4. Control or Normal 20 18 21 11
(without genetic (28.57) (25.71) (30.00) (15.71)
defects)
Figures in parentheses represent percentage
Superscripted alphabets denote level of statistically significant differences of genetic defects values compared with
the controls in the corresponding group. a, b, c, d = Significant at p < 0.001, p