LINARES MEDICAL DEVICES
LINARES MEDICAL DEVICES
LINARES MEDICAL DEVICES
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October 4, 2012<br />
<strong>LINARES</strong> <strong>MEDICAL</strong> <strong>DEVICES</strong><br />
Medical Main Street Conference<br />
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October 4, 2012<br />
<strong>LINARES</strong> <strong>MEDICAL</strong> <strong>DEVICES</strong><br />
Medical Main Street Conference<br />
Miguel Linares—Lead inventor and technical director<br />
Michael Cavanaugh—In House Legal Counsel and Chief Operations Officer<br />
Thomas Bolz—Chief Marketing Officer<br />
Craig Ramsdell, M.D.—Director of Clinical Research<br />
Perry Greene, M.D.—Chief Orthopedic Consultant for Joints and Fractures<br />
Richard Easton, M.D.—Chief Orthopedic Consultant for Spine<br />
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October 4, 2012<br />
<strong>LINARES</strong> <strong>MEDICAL</strong> <strong>DEVICES</strong><br />
Medical Main Street Conference<br />
Over 40 Patents Issued or Pending<br />
New plastic metal hybrid material with antimicrobial activity in testing now<br />
Have already formed a Joint Venture with Signal Medical Corporation, “Signal-LMD,<br />
LLC” in order to develop a ceramic femoral head component with micro-grooves on its<br />
surface in order to increase synovial fluid flow into the joint bearing surface. This<br />
concept is in another Linares Medical Devices Patent.<br />
Business Model is to place Intellectual Property into subsidiary LLCs which are jointly<br />
owned by Linares Medical Devices and the Investor Company. Funds invested are<br />
used to develop the Intellectual Property to the stage of working prototypes which<br />
undergo testing required for FDA approval.<br />
Exit Strategy is outright sale of the devices and IP, or licensing of IP, to large companies<br />
in the orthopedic space<br />
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October 4, 2012<br />
<strong>LINARES</strong> <strong>MEDICAL</strong> <strong>DEVICES</strong> PRESENTS:<br />
Medical Main Street Conference<br />
COMBINATION SPACER INSERT AND SUPPORT FOR PROVIDING INTER-<br />
CERVICAL VERTEBRAL SUPPORT<br />
USPTO Application number: 12/786,088<br />
Publication number: US 2010/0234958 A1<br />
Filing date: May 24, 2010<br />
“A REVOLUTIONARY ALTERNATIVE TO ANTERIOR DISCECTOMY AND<br />
FUSION WHICH INCORPORATES A BALLOON FILLED POLYMER ARTIFICIAL<br />
DISC.”<br />
ONE OF MANY PATENTS THAT CAN BE VIEWED AT:<br />
<strong>LINARES</strong>-MD.COM<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Current Anterior Discectomy and Fusion Operation<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Scale of the Market<br />
“Top Spine Surgeons Reap Royalties, Medicare Bounty”<br />
- By John Carreyrou and Tom McGinty Source: Wall Street<br />
Journal<br />
Medtronic is the biggest maker of spinal implants.<br />
• Last year, its spine business generated world-wide sales of<br />
$3.5 billion…<br />
• …accounting for half of the roughly $7 billion spinal-implant<br />
market.<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
About 250,000 Anterior Cervical Discectomy and Fusions are<br />
performed in the U.S. each year.<br />
Reimbursement to the manufacturers of the equipment for<br />
these operations is at least $5,000 per operation.<br />
• 250,000 operations x $5,000 per operation<br />
= $1,250,000,000 market CONSERVATIVELY<br />
• 10% of this market = $125,000,000 annually<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Unfilled bag-membrane covered plug<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Implant seated in void created by removed damaged disc<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Very flush to front of vertebrae, anchored above and below<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Bladder is inflated with rapidly hardening liquid polymer<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Detail of one of many patented anchoring systems<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Additional Anchoring Systems:<br />
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October 4, 2012<br />
NEXT STEPS<br />
Medical Main Street Conference<br />
• Form “NewCo, LLC” which will be jointly owned by Investor and Linares Medical<br />
Devices<br />
• Fund “NewCo, LLC” with $2,000,000 to be used for:<br />
– Production of several working prototypes of several design variations<br />
– Dynamic load and wear testing on standardized “potted spine” model<br />
– Animal biocompatibility testing and FDA approval<br />
– Expected time for this stage is 15 months<br />
• Exit Strategies:<br />
– Sale of “NewCo, LLC” to large suitor such as Medtronic, or…<br />
– partnership with similar large spine company to take device through<br />
completion of FDA approval process, or…<br />
– Additional round of financing to take it to completion ourselves if this is the<br />
most profitable outcome<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Novel Anchoring Systems<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
More Anchoring Systems<br />
• All feature a lack of screws<br />
• All feature reversibility<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
How the X-Stop Works<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Picture of one of many versions of device in situ with anchoring<br />
mechanism:<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Improvement over x-stop & similar devices:<br />
• Softer plastic with modulus of elasticity similar to bone would be<br />
placed next to bone of adjacent spinous processes.<br />
• Harder plastic would form the interior portions of the device.<br />
• This will decrease the deterioration of the spinous processes<br />
associated with the x-stop device and other similar devices.<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Allows for adjustments, if required.<br />
• Multiple mechanisms for expansion or contraction of the device after<br />
initial placement are covered in this patent application.<br />
• Here are a few representative examples:<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Other examples of mechanisms…<br />
• Many others are represented in the patent application and can be<br />
viewed<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Multiple spinal level designs:<br />
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October 4, 2012<br />
Medical Main Street Conference<br />
Cutaway Views<br />
• Many more are available to be seen in the patent application.<br />
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