Download Entire Catalog - Regis Technologies
Download Entire Catalog - Regis Technologies Download Entire Catalog - Regis Technologies
Silyation Formulations Deriva-Sil • BSTFA:TMCS:TMSI:Pyridine (3:2:3:10) formulation. • Derivatizes sterically-hindered compounds. • Reacts with carbohydrates, hydroxyand keto-steroids, fatty acids, and some amines and amides. • Derivatizations are complete in minutes. Product Size Catalog # Deriva-Sil 10 x 1 ml 270151 BSTFA:TMCS: 25 ml 270152 TMSI:Pyridine (3:2:3:10) Deriva-Sil Concentrate • BSTFA:TMCS:TMSI (3:2:3) concentrate formulation. • Used for applications where pyridine is undesirable (i.e., 3-ketosteroids). Deriva-Sil Concentrate 25 ml 270150 BSTFA:TMCS:TMSI (3:2:3) Hydrox-Sil • HMDS:TMCS:Pyridine (2:1:10) formulation for one-step derivatizations. • Fast formation of the TMS derivatives of organic acids, unhindered alcohols and phenols, and some amines. Hydrox-Sil Reagent 25 ml 270457 HMDS:TMCS:Pyridine (2:1:10) Hydrox-Sil Concentrate • HMDS:TMCS (2:1) concentrate formulation. • Suited for applications where pyridine in Hydrox-Sil is undesirable. Hydrox-Sil Concentrate 25 ml 270458 HMDS:TMCS: (2:1) Derivatization Grade Solvents Derivatization Grade Solvents • High purity reagents packaged under nitrogen. • Sealed with Teflon ® -coated septa, allowing easy access to sample without exposure to moisture and oxygen. Acetonitrile 2 x 25 ml 270010 Pyridine 2 x 25 ml 270013 48 For more information visit www.registech.com/gc
Acylation Reagents Fluorinated Anhydrides: HFBA/PFPA/TFAA Heptafluorobutyric Anhydride/ Pentafluoropropionic Anhydride/Trifluoroacetic Anhydride • Most commonly used for ECD. • Reacts with alcohols, amines, and phenols. • Bases such as triethylamine and trimethylamine can be added to promote reactivity. • Frequently used for the confirmation of drugs of abuse. • HFBA derivatives are the most sensitive to ECD. • PFPA derivatives require the lowest analysis temperatures. • TFAA is the most reactive and volatile of the anhydrides. Product Size Catalog # HFBA 10 x 1 gram 270851 25 gram 270853 PFPA 10 x 1 gram 640110 25 gram 640113 100 gram 640114 TFAA 10 x 1 gram 270841 25 gram 270843 HFBA C 3 F 7 C O C C 3 F 7 + H Y R C 3 F 7 C Y PFPA O O C 2 F 5 C O C C 2 F 5 + H Y R C 2 F 5 C Y TFAA O O O O F 3 C C O C CF 3 + H Y R F 3 C C Y O O O O R + C 3 F 7 C OH O R + C 2 F 5 C OH O R + F 3 C C OH Y = O, NH, NR 1 R, R 1 = Alk, Ar HFBI Heptafluorobutyrylimidazole HFBI 5 x 1 gram 270611 5 gram 270612 • Readily forms derivatives with phenols, alcohols and amines suitable for ECD. • Reactions are fast and mild. • Imidazole is not acidic, so no decomposition or corrosion occurs on columns. MBTFA N-Methyl-N-bis(trifluoroacetamide) • Reacts rapidly under mild conditions with primary and secondary amines. N N O C C 3 F 7 + H Y R C 3 F 7 C Y Y = O, S, NH, NR 1 R, R 1 = Alk, Ar MBTFA 10 x1 gram 270092 5 gram 270091 25 gram 270095 100 gram 270093 O R + N N H • Reacts more slowly with alcohols, phenols, and thiols. • Works well in the analysis of sugars. PFPOH 2,2,3,3,3-Pentafluoropropanol • Used in combination with PFPA to make derivatives of the most common functional groups, especially polyfunctional bio-organic compounds. • Formed derivatives are highly suitable for ECD. PFPOH 5 gram 270815 25 gram 270816 + R 1 C 2 F 5 H 2 C OH HO C C OH R 2 O PFPA R 1 , R 2 = H, Alk, Ar R 1 C 2 F 5 H 2 C O C C CH 2 C 2 F 5 R 2 O For more information visit www.registech.com/gc 49
- Page 1: Chromatography Catalog
- Page 4 and 5: Table of Contents IAM Drug Discover
- Page 6 and 7: Regis Technologies, Inc. Quality Pr
- Page 8 and 9: Chiral Stationary Phases Chiral Chr
- Page 10 and 11: Chiral Stationary Phases Pirkle Chi
- Page 12 and 13: Chiral Stationary Phases Pirkle Chi
- Page 14 and 15: Chiral Stationary Phases Pirkle Chi
- Page 16 and 17: Chiral Stationary Phases Protein-Ba
- Page 18 and 19: Chiral Stationary Phases Crown Ethe
- Page 20 and 21: RAM Direct Injection (Restricted Ac
- Page 22 and 23: ISRP (Internal Surface Reversed Pha
- Page 24 and 25: SPS (Semi-Permeable Surface) SPS Co
- Page 26 and 27: RAM Direct Injection Applications C
- Page 28 and 29: IAM Chromatography Immobilized Arti
- Page 30 and 31: Drug Discovery-Predicting Drug Memb
- Page 32 and 33: IAM.PC.DD2 % Absorption of Inverted
- Page 34 and 35: IAM Fast Screen Mini Column + H 3 C
- Page 36 and 37: IAM Fast Screen Mini Column Regis T
- Page 38 and 39: Ultrapure Ion Pairing Reagents and
- Page 40 and 41: Ultrapure Ion Pairing Reagents and
- Page 42 and 43: Regis Quaternary Amines ( Q-Series)
- Page 44 and 45: Derivatization Derivatization is pr
- Page 46 and 47: Gas Chromatography (GC) Derivatizat
- Page 48 and 49: Silyation Reagents BSA N,O-Bis(trim
- Page 52 and 53: GC Chiral and Specialty Derivatizat
- Page 54 and 55: GC Chiral and Specialty Derivatizat
- Page 56 and 57: Supercritical Fluid Chromatography
- Page 58 and 59: RegisSEP GMP SFC Separation Service
- Page 60 and 61: Custom Synthesis The Chemistry of P
- Page 62 and 63: 60 For more information visit www.r
- Page 64 and 65: Index Listed Alphabetically P Page
- Page 66: Order Information Shipping (continu
Acylation Reagents<br />
Fluorinated Anhydrides:<br />
HFBA/PFPA/TFAA<br />
Heptafluorobutyric Anhydride/<br />
Pentafluoropropionic<br />
Anhydride/Trifluoroacetic Anhydride<br />
• Most commonly used for ECD.<br />
• Reacts with alcohols, amines,<br />
and phenols.<br />
• Bases such as triethylamine and<br />
trimethylamine can be added to<br />
promote reactivity.<br />
• Frequently used for the confirmation<br />
of drugs of abuse.<br />
• HFBA derivatives are the most<br />
sensitive to ECD.<br />
• PFPA derivatives require the lowest<br />
analysis temperatures.<br />
• TFAA is the most reactive and<br />
volatile of the anhydrides.<br />
Product Size <strong>Catalog</strong> #<br />
HFBA 10 x 1 gram 270851<br />
25 gram 270853<br />
PFPA 10 x 1 gram 640110<br />
25 gram 640113<br />
100 gram 640114<br />
TFAA 10 x 1 gram 270841<br />
25 gram 270843<br />
HFBA<br />
C 3 F 7 C O C C 3 F 7 + H Y R C 3 F 7 C Y<br />
PFPA<br />
O<br />
O<br />
C 2 F 5 C O C C 2 F 5 + H Y R C 2 F 5 C Y<br />
TFAA<br />
O<br />
O<br />
O<br />
O<br />
F 3 C C O C CF 3 + H Y R F 3 C C Y<br />
O<br />
O<br />
O<br />
O<br />
R + C 3 F 7 C OH<br />
O<br />
R + C 2 F 5 C OH<br />
O<br />
R + F 3 C C OH<br />
Y = O, NH, NR 1<br />
R, R 1 = Alk, Ar<br />
HFBI<br />
Heptafluorobutyrylimidazole<br />
HFBI 5 x 1 gram 270611<br />
5 gram 270612<br />
• Readily forms derivatives with phenols,<br />
alcohols and amines suitable for ECD.<br />
• Reactions are fast and mild.<br />
• Imidazole is not acidic, so no decomposition<br />
or corrosion occurs on columns.<br />
MBTFA<br />
N-Methyl-N-bis(trifluoroacetamide)<br />
• Reacts rapidly under mild conditions<br />
with primary and secondary amines.<br />
N<br />
N<br />
O<br />
C<br />
C 3 F 7<br />
+ H Y R C 3 F 7 C Y<br />
Y = O, S, NH, NR 1<br />
R, R 1 = Alk, Ar<br />
MBTFA 10 x1 gram 270092<br />
5 gram 270091<br />
25 gram 270095<br />
100 gram 270093<br />
O<br />
R<br />
+<br />
N<br />
N<br />
H<br />
• Reacts more slowly with alcohols,<br />
phenols, and thiols.<br />
• Works well in the analysis of sugars.<br />
PFPOH<br />
2,2,3,3,3-Pentafluoropropanol<br />
• Used in combination with PFPA to<br />
make derivatives of the most common<br />
functional groups, especially<br />
polyfunctional bio-organic compounds.<br />
• Formed derivatives are highly<br />
suitable for ECD.<br />
PFPOH 5 gram 270815<br />
25 gram 270816<br />
+<br />
R 1<br />
C 2 F 5 H 2 C OH HO C C OH<br />
R 2<br />
O<br />
PFPA<br />
R 1 , R 2 = H, Alk, Ar<br />
R 1<br />
C 2 F 5 H 2 C O C C CH 2 C 2 F 5<br />
R 2<br />
O<br />
For more information visit www.registech.com/gc 49
Change language