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Chiral Stationary Phases<br />

Crown Ether Phase<br />

SiO 2 O Si<br />

O<br />

Product Particle Size Column Dimensions <strong>Catalog</strong><br />

ChiroSil ®<br />

Analytical to Preparative Columns<br />

The ChiroSil ® RCA(+) and SCA(-) chiral<br />

Product<br />

Spherical Silica:<br />

ChiroSil ® SCA(-)<br />

Particle Size<br />

5 µm, 100Å<br />

Column Dimensions<br />

15 cm x 4.6 mm i.d.<br />

<strong>Catalog</strong> #<br />

799101<br />

stationary phases were developed by<br />

ChiroSil<br />

RStech Corporation in Daejeon, South<br />

SCA(-) 5 µm, 100Å 25 cm x 4.6 mm i.d. 799102<br />

Korea. This phase is prepared by a covalent<br />

ChiroSil ® SCA(-) 5 µm, 100Å 25 cm x 10.0 mm i.d. 799106<br />

trifunctional bonding of (+) or (-)-<br />

(18-Crown-6)-tetracarboxylic acid as the<br />

chiral selector. The covalent bonding<br />

ensures universal solvent compatibility<br />

and allows operation under ambient<br />

conditions. Columns are available in<br />

both enantiomeric forms to allow the<br />

ChiroSil ® SCA(-)<br />

ChiroSil ® SCA(-)<br />

ChiroSil ® RCA(+)<br />

ChiroSil ® RCA(+)<br />

ChiroSil ® RCA(+)<br />

5 µm, 100Å<br />

5 µm, 100Å<br />

5 µm, 100Å<br />

5 µm, 100Å<br />

5 µm, 100Å<br />

25 cm x 21.1 mm i.d.<br />

25 cm x 30.0 mm i.d.<br />

15 cm x 4.6 mm i.d.<br />

25 cm x 4.6 mm i.d.<br />

25 cm x 10.0 mm i.d.<br />

799105<br />

799107<br />

799001<br />

799002<br />

799006<br />

scientist to invert elution order by<br />

ChiroSil<br />

simply switching columns.<br />

RCA(+) 5 µm, 100Å 25 cm x 21.1 mm i.d. 799005<br />

ChiroSil ® RCA(+) 5 µm, 100Å 25 cm x 30.0 mm i.d. 799007<br />

This chiral stationary phase is the choice<br />

for the separation of amino acids and<br />

compounds containing primary amines<br />

on the analytical or preparative scale.<br />

Phenylglycine<br />

Column:<br />

ChiroSil ® RCA(+) or SCA(-) 15 cm x 4.6 mm<br />

Mobile Phase:<br />

O<br />

(70/30) CH 3 OH/H2O +10 mM H 2 SO 4 and 0.1% TEA<br />

H<br />

Flow Rate:<br />

SiO 2 O Si<br />

N O<br />

1.0 mL/min<br />

C<br />

O<br />

HOOC<br />

Detection: UV 210 nm<br />

O O<br />

Run Time<br />

13.1 min<br />

k’ 1 3.14<br />

O<br />

O<br />

2.60<br />

O O<br />

O<br />

COOH<br />

C<br />

O<br />

N<br />

H<br />

To request a copy of the Chiral HPLC<br />

Application Guide containing additional<br />

Chiral Applications contact us by phone,<br />

800.323.8144 ext. 662<br />

847.967.6000 ext. 662<br />

or e-mail,<br />

sales@registech.com<br />

16<br />

For more information visit www.registech.com/chiral<br />

ChiroSil ® is a trademark of RStech Corporation of Daejeon, South Korea

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