Download Entire Catalog - Regis Technologies
Download Entire Catalog - Regis Technologies Download Entire Catalog - Regis Technologies
Chiral Stationary Phases Pirkle Chiral HPLC Columns Product Particle Size Column Dimensions Catalog # Whelk-O ® 1 SiO 2 O (S,S)-Whelk-O 1 10 µm, 100Å 50 cm x 30.0 mm i.d. 786716 Analytical to Preparative Columns Spherical Silica The Whelk-O 1 is useful for the separation of underivatized enantiomers in a (S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 4.6 mm i.d. 786101 (S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 10.0 mm i.d. 786102 number of families including amides, epoxides, esters, ureas, carbamates, ethers, aziridines, phosphonates, (S,S)-Whelk-O 1 (R,R)-Whelk-O 1 5 µm, 100Å 5 µm, 100Å 25 cm x 30.0 mm i.d. 25 cm x 4.6 mm i.d. 786105 786201 aldehydes, ketones, carboxylic acids, (R,R)-Whelk-O 1 5 µm, 100Å 25 cm x 10.0 mm i.d. 786202 alcohols and non-steroidal antiinflammatory drugs (NSAIDs). This (R,R)-Whelk-O 1 5 µm, 100Å 25 cm x 30.0 mm i.d. 786205 ϖ-electron acceptor/ϖ-electron donor Spherical Kromasil ® Silica phase exhibits an extraordinary degree (S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 4.6 mm i.d. 780101 of generality. The broad versatility (S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 10.0 mm i.d. 780102 observed on the Whelk-O 1 column (S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 30.0 mm i.d. 780103 compares favorably with polysaccharidederived chiral stationary phases. In addition, because Whelk-O 1 is covalently bonded to the support, the phase is compatible with all commonly used mobile phases, including aqueous systems — a distinct advantage over polysaccharide derived chiral stationary phases. Other advantages include column durability, excellent efficiency, (S,S)-Whelk-O 1 (R,R)-Whelk-O 1 (R,R)-Whelk-O 1 (R,R)-Whelk-O 1 (R,R)-Whelk-O 1 (S,S)-Whelk-O 1 (S,S)-Whelk-O 1 5 µm, 100Å 5 µm, 100Å 5 µm, 100Å 5 µm, 100Å 5 µm, 100Å 10 µm, 100Å 10 µm, 100Å 25 cm x 50.0 mm i.d. 25 cm x 4.6 mm i.d. 25 cm x 10.0 mm i.d. 25 cm x 30.0 mm i.d. 25 cm x 50.0 mm i.d. 25 cm x 4.6 mm i.d. 25 cm x 10.0 mm i.d. 780104 780201 780202 780203 780204 786615 786625 ability to invert elution order and (S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 21.1 mm i.d. 786635 excellent preparative capacity. (S,S)-Whelk-O 1 10 µm, 100Å 50 cm x 21.1mm i.d. 786645 (S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 30.0 mm i.d. 786702 (S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 50.0 mm i.d. 786703 H N (S,S)-Whelk-O 1 10 µm, 100Å 50 cm x 50.0 mm i.d. 786704 H 3 C Si CH 3 O NO 2 NO 2 (R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 4.6 mm i.d. 786515 (R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 10.0 mm i.d. 786525 (R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 21.1 mm i.d. 786535 (R,R)-Whelk-O 1 10 µm, 100Å 50 cm x 21.1 mm i.d. 786545 (R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 30.0 mm i.d. 786708 (R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 50.0 mm i.d. 786709 (R,R)-Whelk-O 1 10 µm, 100Å 50 cm x 50.0 mm i.d. 786710 (R,R)-Whelk-O 1 10 µm, 100Å 50 cm x 30.0 mm i.d. 786713 8 For more information visit www.registech.com/chiral Whelk-O is a registered trademark of Regis Technologies, Inc.
Chiral Stationary Phases Pirkle Chiral HPLC Columns Whelk-O ® 2 Analytical to Preparative Columns Our newest addition to the Whelk-O line of chiral stationary phases is the Whelk-O 2. The Whelk-O 2 is the covalent trifunctional version of the Whelk-O 1. The Whelk-O 2 retains the same chiral selector but incorporates a trifunctional linkage to the silica support. In most cases, the enantioselectivity remains the same as that obtained with the Whelk-O 1. Whelk-O 2 was designed to improve the resistance of the stationary phase to hydrolysis while using strong organic modifiers such as trifluoroacetic acid. The Whelk-O 2 is ideal for preparative separations since the material is bonded on 10 µm, 100Å spherical Kromasil silica. This allows the preparative chromatographer to perform method development on an analytical column and immediately scale up to larger diameter columns. Product Particle Size Column Dimensions Catalog # Spherical Kromasil ® Silica (S,S)-Whelk-O 2 10 µm, 100Å 25 cm x 4.6 mm i.d. 786415 (S,S)-Whelk-O 2 10 µm, 100Å 25 cm x 10.0 mm i.d. 786425 (S,S)-Whelk-O 2 10 µm, 100Å 25 cm x 21.1 mm i.d. 786435 (S,S)-Whelk-O 2 10 µm, 100Å 50 cm x 21.1 mm i.d. 786445 (S,S)-Whelk-O 2 10 µm, 100Å 25 cm x 30.0 mm i.d. 786721 (S,S)-Whelk-O 2 10 µm, 100Å 25 cm x 50.0 mm i.d. 786722 (S,S)-Whelk-O 2 10 µm, 100Å 50 cm x 50.0 mm i.d. 786723 (S,S)-Whelk-O 2 10 µm, 100Å 50 cm x 30.0 mm i.d. 786736 (R,R)-Whelk-O 2 10 µm, 100Å 25 cm x 4.6 mm i.d. 786315 (R,R)-Whelk-O 2 10 µm, 100Å 25 cm x 10.0 mm i.d. 786325 (R,R)-Whelk-O 2 10 µm, 100Å 25 cm x 21.1 mm i.d. 786335 (R,R)-Whelk-O 2 10 µm, 100Å 50 cm x 21.1 mm i.d. 786345 (R,R)-Whelk-O 2 10 µm, 100Å 25 cm x 30.0 mm i.d. 786727 (R,R)-Whelk-O 2 10 µm, 100Å 25 cm x 50.0 mm i.d. 786728 (R,R)-Whelk-O 2 10 µm, 100Å 50 cm x 50.0 mm i.d. 786729 (R,R)-Whelk-O 2 10 µm, 100Å 50 cm x 30.0 mm i.d. 786732 O N H SiO 2 O O Si O NO 2 NO 2 Leucine Analytical and Semi-Preparative Columns The -acceptor leucine CSP is based on 3,5-dinitrobenzoyl leucine, covalently bonded to 5 µm aminopropyl silica. Columns derived from either L- or D- leucine are available. This phase demonstrates enhanced enantioselectivities for several classes of compounds, including benzodiazapines. Product Particle Size Column Dimensions Catalog # Spherical Silica: D-Leucine 5 µm, 100Å 25 cm x 4.6 mm i.d. 731054 D-Leucine 5 µm, 100Å 25 cm x 10.0 mm i.d. 731254 D-Leucine 5 µm, 100Å 25 cm x 21.1 mm i.d. 731354 L-Leucine 5 µm, 100Å 25 cm x 4.6 mm i.d. 731041 L-Leucine 5 µm, 100Å 25 cm x 10.0 mm i.d. 731241 L-Leucine 5 µm, 100Å 25 cm x 21.1 mm i.d. 731341 O O H SiO 2 O O Si N H H 3 C NO 2 N NO 2 CH 2 O CH 3 Whelk-O is a registered trademark of Regis Technologies, Inc. For more information visit www.registech.com/chiral 9
- Page 1: Chromatography Catalog
- Page 4 and 5: Table of Contents IAM Drug Discover
- Page 6 and 7: Regis Technologies, Inc. Quality Pr
- Page 8 and 9: Chiral Stationary Phases Chiral Chr
- Page 12 and 13: Chiral Stationary Phases Pirkle Chi
- Page 14 and 15: Chiral Stationary Phases Pirkle Chi
- Page 16 and 17: Chiral Stationary Phases Protein-Ba
- Page 18 and 19: Chiral Stationary Phases Crown Ethe
- Page 20 and 21: RAM Direct Injection (Restricted Ac
- Page 22 and 23: ISRP (Internal Surface Reversed Pha
- Page 24 and 25: SPS (Semi-Permeable Surface) SPS Co
- Page 26 and 27: RAM Direct Injection Applications C
- Page 28 and 29: IAM Chromatography Immobilized Arti
- Page 30 and 31: Drug Discovery-Predicting Drug Memb
- Page 32 and 33: IAM.PC.DD2 % Absorption of Inverted
- Page 34 and 35: IAM Fast Screen Mini Column + H 3 C
- Page 36 and 37: IAM Fast Screen Mini Column Regis T
- Page 38 and 39: Ultrapure Ion Pairing Reagents and
- Page 40 and 41: Ultrapure Ion Pairing Reagents and
- Page 42 and 43: Regis Quaternary Amines ( Q-Series)
- Page 44 and 45: Derivatization Derivatization is pr
- Page 46 and 47: Gas Chromatography (GC) Derivatizat
- Page 48 and 49: Silyation Reagents BSA N,O-Bis(trim
- Page 50 and 51: Silyation Formulations Deriva-Sil
- Page 52 and 53: GC Chiral and Specialty Derivatizat
- Page 54 and 55: GC Chiral and Specialty Derivatizat
- Page 56 and 57: Supercritical Fluid Chromatography
- Page 58 and 59: RegisSEP GMP SFC Separation Service
Chiral Stationary Phases<br />
Pirkle Chiral HPLC Columns<br />
Product Particle Size Column Dimensions <strong>Catalog</strong> #<br />
Whelk-O ® 1<br />
SiO 2 O<br />
(S,S)-Whelk-O 1 10 µm, 100Å 50 cm x 30.0 mm i.d. 786716<br />
Analytical to Preparative Columns<br />
Spherical Silica<br />
The Whelk-O 1 is useful for the separation<br />
of underivatized enantiomers in a<br />
(S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 4.6 mm i.d. 786101<br />
(S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 10.0 mm i.d. 786102<br />
number of families including amides,<br />
epoxides, esters, ureas, carbamates,<br />
ethers, aziridines, phosphonates,<br />
(S,S)-Whelk-O 1<br />
(R,R)-Whelk-O 1<br />
5 µm, 100Å<br />
5 µm, 100Å<br />
25 cm x 30.0 mm i.d.<br />
25 cm x 4.6 mm i.d.<br />
786105<br />
786201<br />
aldehydes, ketones, carboxylic acids,<br />
(R,R)-Whelk-O 1 5 µm, 100Å 25 cm x 10.0 mm i.d. 786202<br />
alcohols and non-steroidal antiinflammatory<br />
drugs (NSAIDs). This<br />
(R,R)-Whelk-O 1 5 µm, 100Å 25 cm x 30.0 mm i.d. 786205<br />
ϖ-electron acceptor/ϖ-electron donor<br />
Spherical Kromasil ® Silica<br />
phase exhibits an extraordinary degree (S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 4.6 mm i.d. 780101<br />
of generality. The broad versatility<br />
(S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 10.0 mm i.d. 780102<br />
observed on the Whelk-O 1 column<br />
(S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 30.0 mm i.d. 780103<br />
compares favorably with polysaccharidederived<br />
chiral stationary phases.<br />
In addition, because Whelk-O 1 is covalently<br />
bonded to the support, the phase<br />
is compatible with all commonly used<br />
mobile phases, including aqueous<br />
systems — a distinct advantage over<br />
polysaccharide derived chiral stationary<br />
phases. Other advantages include<br />
column durability, excellent efficiency,<br />
(S,S)-Whelk-O 1<br />
(R,R)-Whelk-O 1<br />
(R,R)-Whelk-O 1<br />
(R,R)-Whelk-O 1<br />
(R,R)-Whelk-O 1<br />
(S,S)-Whelk-O 1<br />
(S,S)-Whelk-O 1<br />
5 µm, 100Å<br />
5 µm, 100Å<br />
5 µm, 100Å<br />
5 µm, 100Å<br />
5 µm, 100Å<br />
10 µm, 100Å<br />
10 µm, 100Å<br />
25 cm x 50.0 mm i.d.<br />
25 cm x 4.6 mm i.d.<br />
25 cm x 10.0 mm i.d.<br />
25 cm x 30.0 mm i.d.<br />
25 cm x 50.0 mm i.d.<br />
25 cm x 4.6 mm i.d.<br />
25 cm x 10.0 mm i.d.<br />
780104<br />
780201<br />
780202<br />
780203<br />
780204<br />
786615<br />
786625<br />
ability to invert elution order and<br />
(S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 21.1 mm i.d. 786635<br />
excellent preparative capacity.<br />
(S,S)-Whelk-O 1 10 µm, 100Å 50 cm x 21.1mm i.d. 786645<br />
(S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 30.0 mm i.d. 786702<br />
(S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 50.0 mm i.d. 786703<br />
H<br />
N<br />
(S,S)-Whelk-O 1 10 µm, 100Å 50 cm x 50.0 mm i.d. 786704<br />
H 3 C<br />
Si<br />
CH 3<br />
O<br />
NO 2<br />
NO 2<br />
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 4.6 mm i.d. 786515<br />
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 10.0 mm i.d. 786525<br />
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 21.1 mm i.d. 786535<br />
(R,R)-Whelk-O 1 10 µm, 100Å 50 cm x 21.1 mm i.d. 786545<br />
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 30.0 mm i.d. 786708<br />
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 50.0 mm i.d. 786709<br />
(R,R)-Whelk-O 1 10 µm, 100Å 50 cm x 50.0 mm i.d. 786710<br />
(R,R)-Whelk-O 1 10 µm, 100Å 50 cm x 30.0 mm i.d. 786713<br />
8<br />
For more information visit www.registech.com/chiral<br />
Whelk-O is a registered trademark of <strong>Regis</strong> <strong>Technologies</strong>, Inc.
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