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I am thankful to FIST/DST and SAP/UGC for their generous financial and<br />

instrumentation support. Special thanks are due to “National Facility for Drug<br />

Discovery through New Chemical Entities (NCE's) Development & Instrumentation<br />

Support to Small Manufacturing Pharma Enterprises” Programme under Drug &<br />

Pharma Research Support (DPRS) jointly funded by Department of Science &<br />

Technology, New Delhi, Government of Gujarat Industries Commissionerate &<br />

<strong>Saurashtra</strong> <strong>University</strong>, Rajkot. I am also thankful to SAIF, CIL, Chandigarh and NRC,<br />

IISc, Bangalore for providing spectroscopic analysis.<br />

Special thanks to Open Source of Drug Discover project for giving me<br />

financial support and <strong>University</strong> of Grant Commission for finding me as Meritorious<br />

Research Fellow which is really an achievement and helpful task for me.<br />

At Last, I have no words to state anything about my parents but at this<br />

occasion, I would like to thanks my father and mother, without their support,<br />

motivation and understanding it would have been impossible for me to finish my<br />

research work. I sincerely thank to my whole family for encouraging me and<br />

providing every help to fulfill my task. My special gratitude is due to my sister and<br />

their families for their loving support during tenure of my work. To them I dedicate<br />

this thesis.<br />

Anilkumar S. Patel

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