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Chapter 4 Synthesis of highly substituted pyrazolopyrimidine 14. (a) Sullivan, S.K.; Petroski, R.E.; Verge, G.; Gross, R.S.; Foster, A.C.; Grigoriadis, D.E.; J. Pharmacol. Exp. Ther. 2004, 311, 537.(b) Wegner, F.; Deuther-Conrad, W.;. Scheunemann, M.; Brust, P.; Fischer, S.; . Hiller, A; Diekers, M.; Strecker, K.; Wohlfarth, K.; Allgaier, C.; Steinbach, J.; Hoepping, A.; Eur. J. Pharm., 2008, 580 1. (c) Hoepping, A.; Diekers, M.; Deuther-Conrad, W.; Scheunemann, M.; Fischer, S.; Hiller, A.; Wegner, F.; Steinbach, J.; Brus, P.; Bioorg. Med. Chem. 2008, 16, 1184.. 15. (a) Lippa, A.; Czobor, P.;. Stark, J.; Beer, B.;. Kostakis, E.; Gravielle, M.; Bandyopadhyay, S.; Russek, S.J.; Gibbs, T.T.; Farb, D.H.; Skolnick, P.; Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 7380. (b). Mirza, N.R.; Rodgers, R.J.; Mathiasen, L.S.; J. Pharmacol. Exp. Ther. 2006, 316, 1291. 16. Tully W. R.; Gardner, C. R.; Gillespie, R. J.; Westwood, R., J. Med. Chem, 1991, 34, 7 17. Alexandrovich, I, A.; Vasilievich, I. A.; Filippovich, S. N. PCT Int. Appl., 2009093206, 18. Ivachtchenko, A. V.; Golovina, E. S.; Kadieva, M. G.; Koryakova, A. G.; Mitkin, O. D.; Tkachenko, S. E.; Kysil, V. M.; Okun, I.; E. J. Med. Chem. 2011, 46, 1189. 19. Selleri, S.; Bruni, F.; Costagli, C.; Costanzo, A.; Guerrini, G.; Ciciani, G.; Costab B.; Martinib, C.; Bioorg. Med. Chem. 2001, 9, 2661. 20. Tellew, J. E.; Lanier, M.; Moorjani, M.; Lin, E.; Luo, Z.; Slee, D. H.; Zhang, X.; Hoare, S. R. J.; Grigoriadis, D. E.; Denis, Y.; Fabio, St. R. D.; Modugno, E. D.; Saunders, J.; Williams, J. P.; Bioorg. Med. Chem Lett. 2010. 20, 7259. 21. Wang, S. Q.; Fang, L.; Liu, X.; Zhao, K.; Chinese Chemical Letters Vol. 2004, 15, 885. 22. Springer, R. H.; Scholten, M. B.; O’Brien, D. E.; Novinson, T.; Miller, J. P.; Robins, Roland K.; J. Med. Chem. 1982, 25, 235. 23. Frey, R. R.; Curtin, M. L.; Albert, D. H.; Glaser, K. B.; Pease, L. J.; Soni, N. B.; Bouska, J. J.; Reuter, D.; Stewart, K. D.; Marcotte, P.; Bukofzer, G.; Li, J.; Davidsen, S. K.; Michaelides, M. R. J. Med. Chem. 2008, 51, 3777. 24. Ding, R.; He, Y.; Xu, J.; Liu, H.; Wang, X.; Feng, M.; Qi, C.; Zhang, J.; Molecules 2010, 15, 8723. 25. Ahmeda, O. M.; Mohamed, M. A.; Ahmed, R. R.; Ahmed, S.A; E. J. Med. Chem. 2009, 44 3519, 26. Mulakayala, N.; Reddy U; Chaitanya, M.; Chitta, M. H. M. Kumar, S.; Golla, N.; J. Korean Chem. Soc., 2011, 55, 4. 27. Abbas-Temirek, H. H., Assiut University Journal of Chem., 35(1), 37-44; 2006 28. Wu, Y.-C., Li, H.-J.; Liu, L.; Wang, D.; Yang, H.-Z.; Chen, Yong-Jun J. Fluoresc, 2008 18, 357. 29. Danagulyan, G. G.; Boyakhchyan, A. P.; Kirakosyan, V. G.; Chem. of Heterocyclic Compounds, 2010, 46, 6, 30. Ming, L.; Shuwen, W.; Lirong, W.; Huazheng, Y.; Xiuli, Z.; J. Heterocyclic Chem. 2005, 42, 925. 31. Thomas, A.; Chakraborty, M.; H. Ila; Junjappa, H. Tetrahedron, 1990, 46, 577. 32. Mizar, P.; Myrboh, B.; Tetrahedron Letters, 2009, 50,3088. Department of Chemistry, Saurashtra university, Rajkot-360005 156
Chapter 4 Synthesis of highly substituted pyrazolopyrimidine 33. Bassoude, I.; -Raboin, S.-B.; Leger, J.-M.; Jarry, C.; Essassi, E. M.; Guillaumet, G. Tetrahedron, 2011, 67, 2279. 34. Britsun, V. N.; Chemistry of Heterocyclic Compounds, 2008, 44, 10. 35. Kryl’skii, D. V.; Shikhaliev, Kh. S.; Chuvashlev, A. S.; Russian Journal of Organic Chemistry, 2010, 46(3), 410–416. 36. Ahmeda, S. A.; Husseina, A. M.; Hozayena, W. G. M.; El-Ghandoura, A. H. H.; Abdelhamid, A.O.; J. Heterocyclic Chem.,2007. 44, 803. 37. Shaabana, M. R.; Saleh, T. S.; Mayhoub, A. S.; Farag, A. M.; E. J. Med. Chem. 2011, 46 3690. 38. Shaikh, B. M.; Konda, S. G.; Chobe, S. S.; Mandawad, G.G.; Yemul, O.S.;. Dawane, B.S.; J. Chem. Pharm. Res., 2011, 3(2), 435. Department of Chemistry, Saurashtra university, Rajkot-360005 157
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Saurashtra University Re - Accredit
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Statement under O.Ph.D.7 of Saurash
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I am thankful to FIST/DST and SAP/U
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Chapter 4 Synthesis and Characteriz
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Chapter - 1 Palladium Catalyzed Syn
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Chapter 1 Synthesis of functionaliz
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Chapter - 2 Synthesis and Biologica
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Chapter 2 Synthesis of substituted
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Chapter 6 Synthesis of benzodiazepi
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pyrazole derivative were faster and
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Conferences participated 1. “15 t
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