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Extraction Technologies for Medicinal and Aromatic ... - Capacity4Dev

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EXTRACTION TECHNOLOGIES FOR MEDICINAL AND AROMATIC PLANTS<br />

solute. In the medicinal plant industry, generally ball mills <strong>and</strong> fl uid mills are<br />

employed <strong>for</strong> powdering, <strong>and</strong> the optimum particle size is established prior<br />

to the large-scale extraction.<br />

5.3.3 Choice of Solvent<br />

The following factors should be considered when selecting a<br />

solvent <strong>for</strong> commercial use:<br />

• Solvent power (selectivity). Only the active, desired constituents<br />

should be extracted from the plant material, which<br />

means that a high selectivity is required.<br />

• Boiling temperature. The boiling point of the solvent is as<br />

low as possible in order to facilitate removal of the solvent<br />

from the product.<br />

• Reactivity. The solvent should not react chemically with the<br />

extract, nor should it readily decompose.<br />

• Viscosity. A low viscosity of the solvent leads to low pressure<br />

drop <strong>and</strong> good heat <strong>and</strong> mass transfer.<br />

• Safety. The solvent should be non-fl ammable <strong>and</strong> non-corrosive,<br />

<strong>and</strong> should not present a toxic hazard; its disposal<br />

should not imperil the environment.<br />

• Cost. The solvent should be readily available at low cost.<br />

• Vapor pressure. To prevent loss of solvent by evaporation, a<br />

low vapor pressure at operating temperature is required.<br />

• Recovery. The solvent has to be separated easily from the<br />

extract to produce a solvent-free extract.<br />

5.3.4 Conditions <strong>for</strong> <strong>Extraction</strong><br />

Too fi ne particle size may result in problems with packing of<br />

solids <strong>for</strong> extraction, preventing free fl ow of solvent through the solid bed. In<br />

such a case, extraction is more diffi cult, especially when fi nely divided solids<br />

are treated in an un-agitated state. Dispersion of the particles in liquid<br />

solvent by agitation facilitates contact of the solid with the solvent. Agitation,<br />

while giving good extraction, may cause suspension of fine particles in<br />

overfl owing solution.<br />

5.4 Method of Solid-liquid <strong>Extraction</strong><br />

are:<br />

The three principle types of fl ow used in leaching systems<br />

1. Single-stage system<br />

2. Multistage counter-current system<br />

3. Multistage co-current system<br />

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